Product Identification

Product Name

D-Glucurone

Synonyms

(2R)-2-[(2S,3S,4S)-3,4-Dihydroxy-5-oxo-oxolan-2-yl]-2-hydroxy-acetaldehyde
D-Glucurono-3,6-lactone
Dicurone
Glucurono-6,3-lactone
Glucuronolactone
Glycurone

CAS

32449-92-6

Formula

C6H8O6

Molecular Weight

176.12

EINECS

251-053-3

RTECS

LZ8930000

RTECS Class

Drug

Merck

13,4481

Beilstein/Gmelin

83595

Beilstein Reference

5-18-05-00033

Physical and Chemical Properties

Solubility in water

Very soluble

Melting Point

170 - 175

Boiling Point

385

Density

1.76 g/cm3

pKa/pKb

11.96 (pKa)

Partition Coefficient

-2.75

Usage

An important structural component of nearly all connective tissues.

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. Low hazard for usual industrial handling.

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Poison Class

4

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, acrid smoke and fumes.

Transport Information

HS Code

2932 29 80