Product Identification

Product Name

4-Methylpyridin-2-amine

Synonyms

(4-Methylpyridin-2-yl)amine
2-Amino-4-methylpyridine
2-Amino-4-picoline
4-Methyl-2-aminopyridine
4-Methyl-2-pyridylamine
Aminopicoline

CAS

695-34-1

Formula

C6H8N2

Molecular Weight

108.14

EINECS

211-780-9

RTECS

TJ5150000

RTECS Class

Other

Merck

13,465

Beilstein/Gmelin

107066

Beilstein Reference

5-22-09-00325

EC Class

toxic, irritant

Physical and Chemical Properties

Appearance

Off-white flakes.

Solubility in water

Soluble

Melting Point

98

Boiling Point

230.9

Vapor Pressure

0.08 (25 C)

pKa/pKb

6.62 (pKa)

Partition Coefficient

1.08

Heat Of Vaporization

46.4 kJ/mol

Vapor Density

3.73

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not ingest or inhale. Do not allow contact with water.

Hazards Identification

Inhalation

Causes respiratory tract irritation.

Skin

Causes skin irritation. Absorbed through the skin.

Eyes

Causes eye irritation.

Ingestion

Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 23/24/25 36/37/38

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

May cause cardiac stimulation.

Poison Class

3

Fire Fighting Measures

Flash Point

118

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.

Stability and Reactivity

Disposal Code

9

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong bases, acid chlorides, acid anhydrides, strong oxidizing agents, moisture.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2933 39 99