2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER
Uses- Product Name
- 2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER
- CAS No.
- 6065-54-9
- Chemical Name
- 2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER
- Synonyms
- Dimethyl dimethylmalonate;DIMETHYL 2,2-DIMETHYL-MALONATE;dimethyl 2,2-dimethylpropanedioate;Dimethyl 2,2-dimethyl-malonic acid;1,3-dimethyl 2,2-dimethylpropanedioate;2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER;Dimethylpropanedioic acid dimethyl ester;Propanedioic acid, dimethyl-, dimethyl ester;2,2-dimethyl-propanedioic acid dimethyl ester;Propanedioic acid, 2,2-dimethyl-, 1,3-dimethyl ester
- CBNumber
- CB01009846
- Molecular Formula
- C7H12O4
- Formula Weight
- 160.17
- MOL File
- 6065-54-9.mol
2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER Property
- Boiling point:
- 53.5-54.5 °C(Press: 6 Torr)
- Density
- 1.0675 g/cm3
- storage temp.
- 2-8°C
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2917198090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- D474603
- Product name
- 2,2-DimethylmalonicAcidDimethylEster
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FD133302
- Product name
- Dimethyl dimethylmalonate
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FD133302
- Product name
- Dimethyl dimethylmalonate
- Packaging
- 1g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- X0315
- Product name
- Dimethyl2,2-dimethylmalonate
- Packaging
- 1g
- Price
- $131
- Updated
- 2021/12/16
- Product number
- FD133302
- Product name
- Dimethyl dimethylmalonate
- Packaging
- 2g
- Price
- $179
- Updated
- 2021/12/16
2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER Chemical Properties,Usage,Production
Uses
Dimethyl 2,2-dimethylmalonate is a versatile organic compound. It is commonly used as a raw material in the synthesis of pharmaceutical intermediates such as pipemidic acid, fragrance intermediates, and pesticide intermediates.
Synthesis
Synthesis of dimethyl 2,2-dimethylmalonate: a synthesis method of dimethyl 2,2-dimethylmalonate: weigh 104.2g of 2,2-dimethyl-1,3-propanediol, catalyst phosphotungstic acid 0.2g, under constant stirring was added in batches to 340g of 50% hydrogen peroxide solution, which oxidized to the crude 2,2-dimethylmalonate solution, and the molar ratio of 2,2-dimethyl-1,3-propanediol and hydrogen peroxide was 1:5. concentrated and acidified, and then recrystallized with deionized water to obtain 2,2-dimethylmalonate crystal. ,3-propanediol to hydrogen peroxide at a molar ratio of 1:5. Concentrate and acidify, cool to obtain 2,2-dimethylmalonic acid crystals, pump-filter, and then recrystallize with deionized water to obtain 2,2-dimethylmalonic acid pure product in 86% yield. Then 2,2-dimethylmalonic acid was esterified with methanol using sodium hydrosulfate monohydrate as a catalyst with an addition amount of 10% of the mass of 2,2-dimethylmalonic acid, and cyclohexane as a water-carrying agent. The molar ratio of methanol to 2,2-dimethylmalonic acid was 6:1, the reaction temperature was 70-75??C, and the reaction time was 2-4 h. At the end of the reaction, the cyclohexane and methanol were evaporated, and the liquid was separated and set aside for use, and the crude product 2,2-dimethylmalonic acid dimethyl ester was washed with water, and after the liquid was separated, it was dried with anhydrous magnesium sulfate, and distilled under reduced pressure with an oil pump, and the 106-110??C fractions were collected to obtain the product 2,2-dimethylmalonic acid dimethyl ester. Dimethyl 2,2-dimethylmalonate, yield 96%. Purity 99.96%.
2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER Suppliers
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 11999
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9309
- Advantage
- 66
- Tel
- +49 4241 9308 88
- Fax
- +49 4241 9308 89
- info@beckmann-kenko.com
- Country
- Germany
- ProdList
- 478
- Advantage
- 62
- Tel
- 400-188-0725 +86 21 34310725 13611771617
- Fax
- +86 21 34311076
- Country
- China
- ProdList
- 2002
- Advantage
- 57
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 021-50728690 18101878792
- Fax
- +86-21-50728690
- sales@waytrypharms.com
- Country
- China
- ProdList
- 49
- Advantage
- 57
- Tel
- +86-21-60341587
- Fax
- +86-21-61294319
- sales@topbiochem.com
- Country
- China
- ProdList
- 6175
- Advantage
- 58
- Tel
- 18016401466
- Fax
- QQ: 1375988926
- sales@letopharm.com
- Country
- China
- ProdList
- 236
- Advantage
- 58
View Lastest Price from 2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER manufacturers
- Product
- 2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER 6065-54-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 85.0-99.8%
- Supply Ability
- 200kgs
- Release date
- 2020-01-10