ChemicalBook > CAS DataBase List > 5-Bromo-4,7-diazaindole

5-Bromo-4,7-diazaindole

Product Name
5-Bromo-4,7-diazaindole
CAS No.
875781-43-4
Chemical Name
5-Bromo-4,7-diazaindole
Synonyms
2-Bromo-5H-pyrrolo[2,3-b]pyrazine;Upatinib Impurity 94;5-BROMO-4,7-DIAZAINDOLE;5-Bromo-4,7-diazaindole 97%;5H-Pyrrolo[2,3-b]pyrazine, 2-bromo-;4H-Pyrrolo[2,3-b]pyrazine, 2-bromo-;2-broMo-5H-pyrrolo[2,3-b]pyrazine 2-broMo-5H-pyrrolo[3,2-b]pyrazine
CBNumber
CB01012860
Molecular Formula
C6H4BrN3
Formula Weight
198.02
MOL File
875781-43-4.mol
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5-Bromo-4,7-diazaindole Property

Boiling point:
265 °C
Density 
2.00
Flash point:
114 °C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
yellow solid
pka
10.58±0.50(Predicted)
InChI
InChI=1S/C6H4BrN3/c7-5-3-9-6-4(10-5)1-2-8-6/h1-3H,(H,8,9)
InChIKey
KTKMLXBEBKGQGL-UHFFFAOYSA-N
SMILES
C12NC=CC1=NC(Br)=CN=2
CAS DataBase Reference
875781-43-4
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B698910
Product name
2-Bromo-5h-pyrrolo[2,3-b]pyrazine
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
B698910
Product name
2-Bromo-5h-pyrrolo[2,3-b]pyrazine
Packaging
500mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
068431
Product name
5-Bromo-4,7-diazaindole
Purity
>95%
Packaging
1g
Price
$66
Updated
2021/12/16
Synthonix
Product number
B0088
Product name
5-Bromo-4,7-diazaindole
Purity
97.0%
Packaging
1g
Price
$30
Updated
2021/12/16
Matrix Scientific
Product number
068431
Product name
5-Bromo-4,7-diazaindole
Purity
>95%
Packaging
250mg
Price
$45
Updated
2021/12/16
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5-Bromo-4,7-diazaindole Chemical Properties,Usage,Production

Synthesis

Potassium tert-butoxide (3.70 g, 33.0 mmol) was dissolved in THF (80 mL) under N2 protection. A solution of 5-bromo-3 - ((trimethylsilyl) ethynyl) pyrazine-2-amino (9.00 g, 33.0 mmol) in THF (84 mL) was slowly added dropwise over 30 min. After the dropwise addition, the mixture was stirred at room temperature for 30 min, Reflux reaction 1h, Cooled to room temperature and filtered. The filter cake was washed with ethyl acetate (200 mL) and saturated brine (50 mL x 2), and the aqueous phase was combined. And extracted with ethyl acetate (60 mL x 2). The organic phases were combined. The residue was subjected to column chromatography (eluent: PE / EtOAc (v / v) = 3/1) to give 5-Bromo-4,7-diazaindole 5.0 g of a yellow solid.

5-Bromo-4,7-diazaindole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-4,7-diazaindole Suppliers

China 240 Germany 1 India 2 United Kingdom 2 United States 14 Global 259
Hangzhou Chemtrue Bio-Tech Co.,Ltd.
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0571-86828652 18857119830
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0571-83522824
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sales@chemtrue-bio.com
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China
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Guangzhou Anyanren Pharmaceutical Technology Co., Ltd.
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18028661570
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China
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LinkChem Co.,Ltd.
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0086-571-85864795
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
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+86-21-54098501
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View Lastest Price from 5-Bromo-4,7-diazaindole manufacturers

Henan Fengda Chemical Co., Ltd
Product
5-Bromo-4,7-diazaindole 875781-43-4
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-10
Henan Aochuang Chemical Co.,Ltd.
Product
5-Bromo-4,7-diazaindole 875781-43-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-29
Career Henan Chemical Co
Product
5-Bromo-4,7-diazaindole 875781-43-4
Price
US $6.00/KG
Min. Order
1KG
Purity
95%-98%
Supply Ability
100
Release date
2019-09-04

875781-43-4, 5-Bromo-4,7-diazaindoleRelated Search:

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