Exendin-3 (9-39) amide

Product Name: Exendin-3 (9-39) amide
CAS No.: 133514-43-9
Chemical Name: Exendin-3 (9-39) amide
Synonyms: EXENDIN (9-39);EXENDIN 3 (9-39);Exendin-4 (9-39);Hexanal Impurity 5;EXENDIN (9-39) AMIDE;EXENDIN FRAGMENT 9-39;EXENDIN-3 (9-39) AMIDE;EXENDIN [9-39] PEPTIDE;Exendin (9-39) Acetate;Exendin 4 (9-39) amide
CBNumber: CB0109941
Molecular Formula: C149H234N40O47S
Formula Weight: 3369.76
MOL File: 133514-43-9.mol

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Exendin-3 (9-39) amide Property

Density: 1.51
RTECS: LF2460000
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: H2O : 50 mg/mL (14.84 mM; Need ultrasonic)
form: Solid
color: Off-white to pale purple
Water Solubility: Soluble in water at 1mg/ml
InChIKey: WSEVKKHALHSUMB-UHFFFAOYSA-N

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E7269
Product name: Exendin Fragment 9-39
Purity: ≥95% (HPLC)
Packaging: 0.1mg
Price: $404
Updated: 2024/03/01

Alfa Aesar

Product number: J66126
Product name: Exendin (9-39)
Packaging: 0.5mg
Price: $285
Updated: 2023/06/20

Alfa Aesar

Product number: J66126
Product name: Exendin (9-39)
Packaging: 1mg
Price: $466
Updated: 2023/06/20

Cayman Chemical

Product number: 19890
Product name: Exendin-3 (9-39) amide
Purity: ≥95%
Packaging: 500μg
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 19890
Product name: Exendin-3 (9-39) amide
Purity: ≥95%
Packaging: 1mg
Price: $214
Updated: 2024/03/01

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Exendin-3 (9-39) amide Chemical Properties,Usage,Production

Description

Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; K_d = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC₅₀ = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.

Uses

Biological probe.

Uses

Exendin-3 (9-39) is a potent and selective GLP-1 receptor antagonist.

General Description

Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. It also prevents the production of cAMP by GIP. GLP-1, along with GIP, acts as a physiological incretin.

Biochem/physiol Actions

GLP-1 (glucagon-like peptide-1) receptor antagonist. Competitive inhibitor of exendin-3 and exendin-4.

storage

Store at -20°C

Exendin-3 (9-39) amide Preparation Products And Raw materials

Raw materials

Preparation Products

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Exendin-3 (9-39) amide Suppliers

China 120 Europe 1 France 1 Germany 5 Japan 1 Switzerland 1 United Kingdom 1 United States 18 USA 1 Global 149

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
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Chembest Research Laboratories Limited

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GL Biochem (Shanghai) Ltd

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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Cellmano Biotech Limited

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MedChemexpress LLC

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TargetMol Chemicals Inc.

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ShangHai Caerulum Pharma Discovery Co., Ltd.

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Shanghai JONLN Reagent Co., Ltd.

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View Lastest Price from Exendin-3 (9-39) amide manufacturers

Hebei Mojin Biotechnology Co., Ltd

Product: Exendin-3 (9-39) amide 133514-43-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-10-22

Hebei Fengjia New Material Co., Ltd

Product: Exendin-3 (9-39) amide 133514-43-9
Price: US $6.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2024-08-08

Hebei Weibang Biotechnology Co., Ltd

Product: Exendin-3 (9-39) amide 133514-43-9
Price: US $9.90/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 10 tons
Release date: 2021-11-11

133514-43-9, Exendin-3 (9-39) amideRelated Search:

OMEGA-CONOTOXIN MVIIC SDV-Exendin-3/4 EXENDIN-4 (3-39) Rosiptor Alendronate sodium Topiramate EXENDIN-3 EXENDIN 4, FAM-LABELED Exenatide acetate Exendin-3 (9-39) amide

ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2

H-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2

EXENDIN 3 (9-39)

EXENDIN-3 (9-39) AMIDE

EXENDIN (9-39)

EXENDIN (9-39) AMIDE

EXENDIN [9-39] PEPTIDE

EXENDIN FRAGMENT 9-39

DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2

M.W. 3369.79 C149H234N40O47S

ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2: DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2

Exendin 3 (heloderma horridum), 1-de-L-histidine-2-de-L-serine-3-de-L-aspartic acid-4-deglycine-5-de-L-threonine-6-de-L-phenylalanine-7-de-L-threonine-8-de-L-serine-

9-39-Exendin 3(Heloderma horridum)

EXENDIN FRAGMENT 9-39;EXENDIN (9-39)

H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Exendin FragMent 9-39Exendin

H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt

9-39-Exendin 3(Heloderma horridum) (9CI)

Exendin (9-39) Acetate

Exendin 4 (9-39) amide

Asp-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRp-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2, ≥95%(HPLC)

L-Serinamide, L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-p...

Exendin Fragment 9-39 >=95% (HPLC)

Exendin-3 (9-39) amide USP/EP/BP

GCGR,Glucagon Receptor,Avexitide,Inhibitor,inhibit

Exendin-3 (9-39) amide/Avexitide

Hexanal Impurity 5

Asp-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TR|p|-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2

Exendin-4 (9-39)

H-DL-Asp-DL-Leu-DL-Ser-DL-Lys-DL-Gln-DL-Met-DL-Glu-DL-Glu-DL-Glu-DL-Ala-DL-Val-DL-Arg-DL-Leu-DL-Phe-DL-xiIle-DL-Glu-DL-Trp-DL-Leu-DL-Lys-DL-Asn-Gly-Gly-DL-Pro-DL-Ser-DL-Ser-Gly-DL-Ala-DL-Pro-DL-Pro-DL-Pro-DL-Ser-NH2

133514-43-9

C149H234N40O47S

C149H234N40O47S1

Hormones

Obesity Research

Exendin

Cytokines, Growth Factors and Hormones

BioChemical

Cell Biology

Cell Signaling and Neuroscience

Peptide

GLP-1 Receptor LigandsObesity Research

Cytokines Growth Factors and Hormones (Obesity)

ExendinPeptides for Cell Biology

Hormones

Obesity Peptides

Obesity Research

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Glucagon receptor and related