Exendin-3 (9-39) amide
- Product Name
- Exendin-3 (9-39) amide
- CAS No.
- 133514-43-9
- Chemical Name
- Exendin-3 (9-39) amide
- Synonyms
- EXENDIN (9-39);EXENDIN 3 (9-39);Exendin-4 (9-39);Hexanal Impurity 5;EXENDIN (9-39) AMIDE;EXENDIN FRAGMENT 9-39;EXENDIN-3 (9-39) AMIDE;EXENDIN [9-39] PEPTIDE;Exendin (9-39) Acetate;Exendin 4 (9-39) amide
- CBNumber
- CB0109941
- Molecular Formula
- C149H234N40O47S
- Formula Weight
- 3369.76
- MOL File
- 133514-43-9.mol
Exendin-3 (9-39) amide Property
- Density
- 1.51
- RTECS
- LF2460000
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- H2O : 50 mg/mL (14.84 mM; Need ultrasonic)
- form
- Solid
- color
- Off-white to pale purple
- Water Solubility
- Soluble in water at 1mg/ml
- InChIKey
- WSEVKKHALHSUMB-UHFFFAOYSA-N
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- E7269
- Product name
- Exendin Fragment 9-39
- Purity
- ≥95% (HPLC)
- Packaging
- 0.1mg
- Price
- $404
- Updated
- 2024/03/01
- Product number
- J66126
- Product name
- Exendin (9-39)
- Packaging
- 0.5mg
- Price
- $285
- Updated
- 2023/06/20
- Product number
- J66126
- Product name
- Exendin (9-39)
- Packaging
- 1mg
- Price
- $466
- Updated
- 2023/06/20
- Product number
- 19890
- Product name
- Exendin-3 (9-39) amide
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $152
- Updated
- 2024/03/01
- Product number
- 19890
- Product name
- Exendin-3 (9-39) amide
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $214
- Updated
- 2024/03/01
Exendin-3 (9-39) amide Chemical Properties,Usage,Production
Description
Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.
Uses
Biological probe.
Uses
Exendin-3 (9-39) is a potent and selective GLP-1 receptor antagonist.
General Description
Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. It also prevents the production of cAMP by GIP. GLP-1, along with GIP, acts as a physiological incretin.
Biochem/physiol Actions
GLP-1 (glucagon-like peptide-1) receptor antagonist. Competitive inhibitor of exendin-3 and exendin-4.
storage
Store at -20°C
Exendin-3 (9-39) amide Preparation Products And Raw materials
Raw materials
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View Lastest Price from Exendin-3 (9-39) amide manufacturers
- Product
- Exendin-3 (9-39) amide 133514-43-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2024-10-22
- Product
- Exendin-3 (9-39) amide 133514-43-9
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2024-08-08
- Product
- Exendin-3 (9-39) amide 133514-43-9
- Price
- US $9.90/KG
- Min. Order
- 100KG
- Purity
- 99%
- Supply Ability
- 10 tons
- Release date
- 2021-11-11