Declopramide

Product Name: Declopramide
CAS No.: 891-60-1
Chemical Name: Declopramide
Synonyms: IMO-B;OXI-104;Declopramide;3-Chloroprocainamide;4-amino-3-chloro-N-(2-diethylaminoethyl)benzamide;4-azanyl-3-chloro-N-(2-diethylaminoethyl)benzamide;Benzamide, 4-amino-3-chloro-N-[2-(diethylamino)ethyl]-
CBNumber: CB01178430
Molecular Formula: C13H20ClN3O
Formula Weight: 269.77
MOL File: 891-60-1.mol

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Declopramide Property

Boiling point:: 404.2±45.0 °C(Predicted)
Density: 1.153±0.06 g/cm3(Predicted)
pka: 13.76±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific

Product number: 4238CA
Product name: Declopramide
Packaging: 100mg
Price: $453
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0014462
Product name: DECLOPRAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $500.3
Updated: 2021/12/16

AK Scientific

Product number: 4238CA
Product name: Declopramide
Packaging: 250mg
Price: $604
Updated: 2021/12/16

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Declopramide Chemical Properties,Usage,Production

Uses

Declopramide (3-Chloroprocainamide) is an orally active antitumor agent, which inhibits proliferation of cancer cells HL60 and K562, and inhibits tumor growth of human brain astrocytoma (T24) in mouse model. Declopramide induces apoptosis, inhibits NF-κB through inhibition of IκBα degradation. Declopramide serves also as chemosensitizer in research[1][2][3].

References

[1] Hua J, et al., Comparison of antitumor activity of declopramide (3-chloroprocainamide) and N-acetyl-declopramide. Anticancer Res. 1999 Jan-Feb;19(1A):285-90. PMID:10226556
[2] Hua J, et al., Pharmacokinetics and central nervous system toxicity of declopramide (3-chloroprocainamide) in rats and mice. Anticancer Drugs. 1999 Jan;10(1):79-88. DOI:10.1097/00001813-199901000-00010
[3] Lindgren H, et al., Differential usage of IkappaBalpha and IkappaBbeta in regulation of apoptosis versus gene expression. Biochem Biophys Res Commun. 2003 Jan 31;301(1):204-11. DOI:10.1016/s0006-291x(02)03012-7

Declopramide Preparation Products And Raw materials

Raw materials

Preparation Products

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Declopramide Suppliers

China 6 India 1 United States 1 Global 8

Block Chemical Technology (Shanghai) Co., LTD

Tel: 021-20432219 13918097649
Fax: QQ79021576
Email: li_jinfei@acblock-lab.com
Country: China
ProdList: 9964
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29257
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Lanospharma Laboratories Co.,Ltd

Tel: --
Fax: --
Email: sales@lanospharma.com
Country: China
ProdList: 6329
Advantage: 56

891-60-1, DeclopramideRelated Search:

Metoclopramide hydrochloride Metoclopramide monohydrochloride monohydrate NEMONAPRIDE Lintopride batanopride Cloxacepride 4-AMINO-N-1-AZABICYCLO[2.2.2]OCT-3-YL-5-CHLORO-2-METHOXYBENZAMIDE HYDROCHLORIDE O-DESMETHYL METOCLOPRAMIDE, HYDROCHLORIDE pancopride Declopramide PERALOPRIDE Mezacopride YM-09151-2, [N-METHYL-3H]- Benzamide, 4-amino-5-chloro-N-(2-(cyclopropylethylamino)ethyl)-2-metho xy- 5-Chloro-N-(2-(diethylamino)ethyl)-4-((4,5-dihydro-2-oxazolyl)amino)-2 -methoxybenzamide Benzamide, 4-amino-5-chloro-2-methoxy-N-(2-(4-(2-pyridinyl)-1-piperazi nyl)ethyl)- Benzamide, 5-chloro-N-(2-(diethylamino)ethyl)-4-((4,5-dihydro-1H-imida zol-2-yl)amino)-2-methoxy- Benzamide, 5-chloro-N-(2-(diethylamino)ethyl)-4-((4,5-dihydro-2-thiazo lyl)amino)-2-methoxy-

Declopramide

4-amino-3-chloro-N-(2-diethylaminoethyl)benzamide

4-azanyl-3-chloro-N-(2-diethylaminoethyl)benzamide

3-Chloroprocainamide

IMO-B

OXI-104

Benzamide, 4-amino-3-chloro-N-[2-(diethylamino)ethyl]-

891-60-1