CYCLO(-PRO-VAL)

ChemicalBook > CAS DataBase List > CYCLO(-PRO-VAL)

Product Name: CYCLO(-PRO-VAL)
CAS No.: 2854-40-2
Chemical Name: CYCLO(-PRO-VAL)
Synonyms: Cyclo(Val-Pro);CYCLO(-PRO-VAL);Cyclo(L-Val-L-Pro-);Cyclo(L-Pro-L-Val-);2854-40-2/5654-87-5;Cyclo(L-prolyl-L-valyl);CYCLO(L-PROLYL-L-VALINE);Cyclo(L-Pro-L-Val),CYCLO(-PRO-VAL);(3S,8aS)-3-Isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione;(3S,8aα)-3β-Isopropyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione
CBNumber: CB0132749
Molecular Formula: C10H16N2O2
Formula Weight: 196.25
MOL File: 2854-40-2.mol

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CYCLO(-PRO-VAL) Property

Melting point:: 190-192 °C
Boiling point:: 420.7±34.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly, Sonicated), Methanol (Slightly)
form: Solid
pka: 13.15±0.40(Predicted)
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27961
Product name: Cyclo(L-Pro-L-Val)
Packaging: 25mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 27961
Product name: Cyclo(L-Pro-L-Val)
Packaging: 50mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 27961
Product name: Cyclo(L-Pro-L-Val)
Packaging: 100mg
Price: $129
Updated: 2024/03/01

Cayman Chemical

Product number: 27961
Product name: Cyclo(L-Pro-L-Val)
Packaging: 250mg
Price: $283
Updated: 2024/03/01

TRC

Product number: C989825
Product name: Cyclo(L-prolyl-L-valyl)
Packaging: 25mg
Price: $335
Updated: 2021/12/16

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CYCLO(-PRO-VAL) Chemical Properties,Usage,Production

Description

Cyclo(L-Pro-L-Val) is a diketopiperazine that has been found in the marine sponge T. ignis, the bacterium B. pumilus, and the fungus A. fumigatus, among others. It is active against the bacteria S. aureus and B. subtilis (MICs = 16.3 and 18.2 μg/ml, respectively) but not E. coli (MIC = >20 μg/ml). Cyclo(L-Pro-L-Val) inhibits activation of a LuxR-dependent E. coli biosensor by the quorum-sensing molecule 3-oxo-hexanoyl-homoserine lactone (IC₅₀ = 0.4 mM) and activates violacein pigment production in the LuxR-dependent C. violaceum acyl homoserine lactone reporter strain CV026. However, it does not activate or inhibit lacZ-based reporter fusions in S. liquefaciens or A. tumefaciens.

Uses

Cyclo(L-Pro-L-Val) is a diketopiperazine formed by the fusion of valine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Pro-L-Val) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Pro-L-Val) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of the cyclo(L-Pro-L-Val) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.

Uses

Cyclo(L-prolyl-L-valyl) is a metabolite found in various marine fungi and bacteria. It is a diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus.

Definition

ChEBI: Cyclo(L-Pro-L-Val) is a piperazinone. It has a role as a metabolite.

CYCLO(-PRO-VAL) Preparation Products And Raw materials

Raw materials

Preparation Products

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2854-40-2, CYCLO(-PRO-VAL)Related Search:

CYCLO(-PHE-PRO) MACULOSIN Cyclo(-Phe-Tyr) CYCLO(-MET-PRO) cyclo(Pro-Ser) cyclo(Pro-Asp) cyclo(Pro-Glu) cyclo(Pro-Lys) cyclo(Pro-Asn) cyclo(Pro-Gln) cyclo(Pro-Cys) (S)-3-Isopropyl-2,5-piperazinedione CYCLO(-PRO-VAL) 3-ISOPROPYL-PIPERAZIN-2-ONE (R)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-1(2H)-ONE (3S)-3-ISOPROPYL-1-METHYLPIPERAZINE (2S)-ISOPROPYLPIPERAZINE

CYCLO(-PRO-VAL)

(3S,8aS)-3-Isopropyl-6,7,8,8aα-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione

(3S,8aS)-3β-Isopropyl-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4(2H,3H)-dione

(3S,8aS)-Octahydro-3-(1-methylethyl)pyrrolo[1,2-a]pyrazine-1,4-dione

(3S,8aα)-3β-Isopropyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione

Cyclo(L-Pro-L-Val-)

Cyclo(L-Val-L-Pro-)

Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-, (3S,8aS)-

(3S,8aS)-3-propan-2-yl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Cyclo(L-prolyl-L-valyl)

CYCLO(L-PROLYL-L-VALINE)

(3S,8aS)-3-(propan-2-yl)-octahydropyrrolo[1,2-a]p yrazine-1,4-dione

(3S,8aS)-3-Isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Cyclo(L-Pro-L-Val),CYCLO(-PRO-VAL)

2854-40-2/5654-87-5

Cyclo(Val-Pro)

2854-40-2