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atherospermine

Product Name: atherospermine
CAS No.: 5531-98-6
Chemical Name: atherospermine
Synonyms: atherospermine;atherosclerosis;Atherosperminine;Atherosperminine, 10 mM in DMSO;N,N-Dimethyl-3,4-dimethoxyphenanthrene-1-ethanamine;3,4-Dimethoxy-N,N-dimethyl-1-phenanthreneethanamine;1-Phenanthreneethanamine, 3,4-dimethoxy-N,N-dimethyl-;2-(3,4-Dimethoxyphenanthren-1-yl)-N,N-dimethylethan-1-amine;inhibit,Atherosperminine,Parasite,antiplasmodial,Inhibitor,pro-oxidant,reductants,Atherospermine,trachealis
CBNumber: CB01348792
Molecular Formula: C20H23NO2
Formula Weight: 309.4
MOL File: 5531-98-6.mol

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atherospermine Property

Melting point:: 199 °C
Boiling point:: 466.1±35.0 °C(Predicted)
Density: 1.109±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 9.15±0.28(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0134967
Product name: Atherosperminine
Packaging: 1mg
Price: $100
Updated: 2021/12/16

Arctom

Product number: CFN91008
Product name: Atherosperminine
Packaging: 10mg
Price: $268
Updated: 2021/12/16

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atherospermine Chemical Properties,Usage,Production

Uses

Atherosperminine (Atherospermine) is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC50 of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical DPPH, with an IC50 of 29.56 μg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis[1].

Definition

ChEBI: Atherosperminine is an alkaloid.

IC 50

Plasmodium

References

[1] Ayu Afiqah Nasrullah, et al. Antiplasmodial Alkaloids from the Bark of Cryptocarya nigra (Lauraceae). Molecules. 2013 Jul; 18(7): 8009–8017. DOI:10.3390/molecules18078009
[2] C H Lin, et al. The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma. Eur J Pharmacol. 1993 Jun 11;237(1):109-16. DOI:10.1016/0014-2999(93)90099-4

atherospermine Preparation Products And Raw materials

Raw materials

Preparation Products

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atherospermine

3,4-Dimethoxy-N,N-dimethyl-1-phenanthreneethanamine

Atherosperminine

N,N-Dimethyl-3,4-dimethoxyphenanthrene-1-ethanamine

1-Phenanthreneethanamine, 3,4-dimethoxy-N,N-dimethyl-

atherosclerosis

inhibit,Atherosperminine,Parasite,antiplasmodial,Inhibitor,pro-oxidant,reductants,Atherospermine,trachealis

2-(3,4-Dimethoxyphenanthren-1-yl)-N,N-dimethylethan-1-amine

Atherosperminine, 10 mM in DMSO

5531-98-6