5-hydroxyeicosatetraenoic acid lactone
- Product Name
- 5-hydroxyeicosatetraenoic acid lactone
- CAS No.
- 81517-87-5
- Chemical Name
- 5-hydroxyeicosatetraenoic acid lactone
- Synonyms
- 5-hydroxyeicosatetraenoic acid lactone;6-[(1E,3Z,6Z,9Z)-pentadeca-1,3,6,9-tetraenyl]oxan-2-one;2H-Pyran-2-one, tetrahydro-6-(1E,3Z,6Z,9Z)-1,3,6,9-pentadecatetraen-1-yl-
- CBNumber
- CB01399103
- Molecular Formula
- C20H30O2
- Formula Weight
- 302.45
- MOL File
- 81517-87-5.mol
5-hydroxyeicosatetraenoic acid lactone Property
- Boiling point:
- 445.7±34.0 °C(Predicted)
- Density
- 0.979±0.06 g/cm3(Predicted)
- solubility
- DMF: 50 mg/ml
DMSO: 50 mg/ml
Ethanol: 50 mg/mlPBS pH 7.2: 1 mg/ml - form
- Clear to light-yellow liquid.
5-hydroxyeicosatetraenoic acid lactone Chemical Properties,Usage,Production
Uses
(±)5-HETE lactone is the racemate of 5-HETE lactone. 5-HETE lactone is a metabolite generated by a series of enzymatic reactions of arachidonic acid, and is also a substrate of paraoxonase-1 (PON1). 5-HETE lactone can be used in the study of B cell activation[1][2].
References
[1] Tao C, et al. Reactivity of tricarbonyl (pentadienyl) iron (1+) cations: enantioselective synthesis of 5-HETE methyl ester[J]. The Journal of Organic Chemistry, 1993, 58(8): 2134-2143.
[2] Picardo C M. The hydrolysis of 5-HETE lactone by paraoxonase 1 and its stability in serum[M]. 2007.
[3] F. A. J. KERDESKY. ChemInform Abstract: Synthesis and 5-Lipoxygenase Inhibitory Activity of 5-Hydroperoxy- 6,8,11,14-eicosatetraenoic Acid Analogues.[J]. ChemInform, 1987, 18 50. DOI: 10.1002/chin.198750355
5-hydroxyeicosatetraenoic acid lactone Preparation Products And Raw materials
Raw materials
Preparation Products
5-hydroxyeicosatetraenoic acid lactone Suppliers
- Tel
- 800-364-9897
- sales@caymanchem.com
- Country
- China
- ProdList
- 6838
- Advantage
- 58