QUIN 2-AM
- Product Name
- QUIN 2-AM
- CAS No.
- 83104-85-2
- Chemical Name
- QUIN 2-AM
- Synonyms
- QUIN 2-AM;Quin 2 Am Ester;Acetoxymethyl ester;quin2-acetoxymethylester;Quin-2, AM *CAS 83104-85-2*;QUIN-2 TETRAACETOXYMETHYL ESTER;8-Amino-2-[(2-amino-5-methylphenoxy)-methyl]-6-methoxyquinoline-N,N,N',N'-tetraacetic acid;Tetrakis(acetoxymethyl) 8-amino-2-[(2-amino-5-methylphenoxy)methyl]-6-methoxyquinoline-N,N,N′,N′-tetraacetate;2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrakis(acetoxymethyl ester);2-[(2-AMINO-5-METHYLPHENOXY)METHYL]-6-METHOXY-8-AMINO-QUINOLINE-N,N,N',N'-TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL-ESTER)
- CBNumber
- CB0158606
- Molecular Formula
- C38H43N3O18
- Formula Weight
- 829.76
- MOL File
- 83104-85-2.mol
QUIN 2-AM Property
- Density
- 1.360
- Flash point:
- 113 °C
- storage temp.
- −20°C
- solubility
- DMSO: soluble
- form
- A solid
- λmax
- 348 nm
- Biological Applications
- Calcium indicator
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 20422
- Product name
- Quin-2 AM
- Purity
- ≥90%
- Packaging
- 500μg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- 20422
- Product name
- Quin-2 AM
- Purity
- ≥90%
- Packaging
- 1mg
- Price
- $165
- Updated
- 2024/03/01
- Product number
- Q796703
- Product name
- Quin2-AM
- Packaging
- 2.5mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- Q796703
- Product name
- Quin2-AM
- Packaging
- 1mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- 3974BA
- Product name
- Quin2-acetoxymethylester
- Packaging
- 1mg
- Price
- $280
- Updated
- 2021/12/16
QUIN 2-AM Chemical Properties,Usage,Production
Description
Quin-2 AM is a cell-permeant acetoxymethyl ester of the high affinity fluorescent calcium indicator quin-2 . As quin-2 AM enters cells, it is hydrolyzed by intracellular esterases to produce quin-2. Quin-2 binds calcium with a Kd value of 115 nM. It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation and emission maxima for quin-2 are 339 and 492 nm, respectively.
Uses
Fluorescent probe for measurement of calcium in biological systems and for selected divalent cations.
Uses
2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester)
Uses
Quin 2-AM is a cell permeable fluorescent probe for Ca2+ that gives a large shift in the UV absorption spectrum and a 20-fold increase in fluorescence upon Ca2+ binding.
QUIN 2-AM Preparation Products And Raw materials
Raw materials
Preparation Products
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