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QUIN 2-AM

Product Name
QUIN 2-AM
CAS No.
83104-85-2
Chemical Name
QUIN 2-AM
Synonyms
QUIN 2-AM;Quin 2 Am Ester;Acetoxymethyl ester;quin2-acetoxymethylester;Quin-2, AM *CAS 83104-85-2*;QUIN-2 TETRAACETOXYMETHYL ESTER;8-Amino-2-[(2-amino-5-methylphenoxy)-methyl]-6-methoxyquinoline-N,N,N',N'-tetraacetic acid;Tetrakis(acetoxymethyl) 8-amino-2-[(2-amino-5-methylphenoxy)methyl]-6-methoxyquinoline-N,N,N′,N′-tetraacetate;2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrakis(acetoxymethyl ester);2-[(2-AMINO-5-METHYLPHENOXY)METHYL]-6-METHOXY-8-AMINO-QUINOLINE-N,N,N',N'-TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL-ESTER)
CBNumber
CB0158606
Molecular Formula
C38H43N3O18
Formula Weight
829.76
MOL File
83104-85-2.mol
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QUIN 2-AM Property

Density 
1.360
Flash point:
113 °C
storage temp. 
−20°C
solubility 
DMSO: soluble
form 
A solid
λmax
348 nm
Biological Applications
Calcium indicator
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
1-8-10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20422
Product name
Quin-2 AM
Purity
≥90%
Packaging
500μg
Price
$110
Updated
2024/03/01
Cayman Chemical
Product number
20422
Product name
Quin-2 AM
Purity
≥90%
Packaging
1mg
Price
$165
Updated
2024/03/01
TRC
Product number
Q796703
Product name
Quin2-AM
Packaging
1mg
Price
$120
Updated
2021/12/16
TRC
Product number
Q796703
Product name
Quin2-AM
Packaging
2.5mg
Price
$240
Updated
2021/12/16
AK Scientific
Product number
3974BA
Product name
Quin2-acetoxymethylester
Packaging
1mg
Price
$280
Updated
2021/12/16
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QUIN 2-AM Chemical Properties,Usage,Production

Description

Quin-2 AM is a cell-permeant acetoxymethyl ester of the high affinity fluorescent calcium indicator quin-2 . As quin-2 AM enters cells, it is hydrolyzed by intracellular esterases to produce quin-2. Quin-2 binds calcium with a Kd value of 115 nM. It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation and emission maxima for quin-2 are 339 and 492 nm, respectively.

Uses

Fluorescent probe for measurement of calcium in biological systems and for selected divalent cations.

Uses

2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester)

Uses

Quin 2-AM is a cell permeable fluorescent probe for Ca2+ that gives a large shift in the UV absorption spectrum and a 20-fold increase in fluorescence upon Ca2+ binding.

QUIN 2-AM Preparation Products And Raw materials

Raw materials

Preparation Products

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QUIN 2-AM Suppliers

China 37 Germany 1 India 1 Switzerland 3 United Kingdom 1 United States 12 Global 55
Chemodex Ltd.
Tel
--
Fax
--
Email
info@chemodex.com
Country
Switzerland
ProdList
1549
Advantage
50
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74

83104-85-2, QUIN 2-AMRelated Search:

N-[2-[(Acetyloxy)methoxy]-2-oxoethyl]-N-[2-[2-[5-[6-[(acetyloxy)methoxy]-3-oxo-3H-xanthen-9-yl]-2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]phenoxy]ethoxy]phenyl]glycine (acetyloxy)methyl ester Fluo 3-AM 2-METHOXY-N-METHYANILINE 2-Anilinoethanol 3-Dimethylaminoanisole Diethanolamine N-(2-Hydroxyethyl)-N-methylaniline Anilinoacetic acid N-Methyliminodiacetic acid 3-ETHYLAMINOPHENOL 2-[(2-amino-5-methylph2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium saltenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n N,N-DIMETHYLGLYCINE METHYL ESTER Iminodiacetic acid N-Ethyl-N-hydroxyethylaniline 3-METHOXY-N-METHYLANILINE 2-METHYLAMINOPHENOL N,N-BIS(2-HYDROXYETHYL)-3-METHOXYANILINE 8-Aminoquinaldine

  • QUIN 2-AM
  • QUIN-2 TETRAACETOXYMETHYL ESTER
  • 2-[(2-AMINO-5-METHYLPHENOXY)METHYL]-6-METHOXY-8-AMINO-QUINOLINE-N,N,N',N'-TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL-ESTER)
  • 2-[[2-BIS(CARBOXYMETHYL)AMINO-5-METHYLPHENOXY]-METHYL]-6-METHOXY-8-BIS(CARBOXYMETHYL)AMINOQUINOLINE TETRAKIS(ACETOXYMETHYL) ESTER
  • quin2-acetoxymethylester
  • 2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrakis(acetoxymethyl ester)
  • 2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,Nμ,Nμ-tetraacetic acid tetrakis(acetoxymethyl ester), 2-{[2-Bis(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline tetrakis(acetoxymethyl) ester
  • 8-Amino-2-[(2-amino-5-methylphenoxy)-methyl]-6-methoxyquinoline-N,N,N',N'-tetraacetic acid
  • N-[2-[[8-[Bis(carboxymethyl)amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-(carboxymethyl)glycine tetra(acetoxymethyl ester)
  • N-[2-[[8-[Bis[[(acetoxymethoxy)carbonyl]methyl]amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-[[(acetoxymethoxy)carbonyl]methyl]glycine acetoxymethyl ester
  • N-[2-[(Acetyloxy)methoxy]-2-oxoethyl]-N-[2-[[8-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]glycine (acetyloxy)methyl ester
  • 2-[(2-amino-5-methylphenoxy)methyl]- 6-methoxy-8-aminoquinoline-n,n,n0,n0-tetraacetic acid Tetrakis(acetoxymethyl Ester)
  • Quin 2 Am Ester
  • Acetoxymethyl ester
  • Quin-2, AM *CAS 83104-85-2*
  • Glycine, N-(2-((acetyloxy)methoxy)-2-oxoethyl)-N-(2-((8-(bis(2-((acetyloxy)methoxy)-2-oxoethyl)amino)-6-methoxy-2-quinolinyl)methoxy)-4-methylphenyl)-, (acetyloxy)methyl ester
  • 2-{[2-Bis(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline tetrakis(acetoxymethyl) ester
  • Tetrakis(acetoxymethyl) 8-amino-2-[(2-amino-5-methylphenoxy)methyl]-6-methoxyquinoline-N,N,N′,N′-tetraacetate
  • acetyloxymethyl 2-[N-[2-(acetyloxymethoxy)-2-oxoethyl]-2-[[8-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-6-methoxyquinolin-2-yl]methoxy]-4-methylanilino]acetate
  • 83104-85-2
  • C38H43N3O18
  • Quinoline