2,5-Dimethyl pyrazine
- Product Name
- 2,5-Dimethyl pyrazine
- CAS No.
- 123-32-0
- Chemical Name
- 2,5-Dimethyl pyrazine
- Synonyms
- 2,5-DIMETHYLPYRAZINE;2,5-Dimethylprazin;Pyrazine,2,5-dimethyl-;2,5-Dimethyl;Structural formula;2,5-Dimethylpiazine;2,5-dimethyl-pyrazin;tomfor;KETINE;GLYCOLINE
- CBNumber
- CB0159355
- Molecular Formula
- C6H8N2
- Formula Weight
- 108.14
- MOL File
- 123-32-0.mol
2,5-Dimethyl pyrazine Property
- Melting point:
- 15°C
- Boiling point:
- 155 °C (lit.)
- Density
- 0.99 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.502(lit.)
- FEMA
- 3272 | 2,5-DIMETHYLPYRAZINE
- Flash point:
- 147 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Liquid
- pka
- 2.21±0.10(Predicted)
- Specific Gravity
- 0.990
- color
- Clear colorless to pale yellow
- PH
- 7 (H2O)
- Odor
- at 0.10 % in dipropylene glycol. nutty roasted baked potato
- Odor Type
- chocolate
- Sensitive
- Hygroscopic
- JECFA Number
- 766
- BRN
- 107052
- Dielectric constant
- 2.4399999999999999
- LogP
- 0.64
- CAS DataBase Reference
- 123-32-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Pyrazine, 2,5-dimethyl-(123-32-0)
- EPA Substance Registry System
- Pyrazine, 2,5-dimethyl- (123-32-0)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38-R22
- Safety Statements
- 26-36
- RIDADR
- NA 1993 / PGIII
- WGK Germany
- 3
- RTECS
- UQ2800000
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29339990
N-Bromosuccinimide Price
- Product number
- W327204
- Product name
- 2,5-Dimethylpyrazine
- Purity
- ≥98%, FG
- Packaging
- 100g
- Price
- $91.8
- Updated
- 2024/03/01
- Product number
- W327204
- Product name
- 2,5-Dimethylpyrazine
- Purity
- ≥98%, FG
- Packaging
- 500g
- Price
- $256
- Updated
- 2024/03/01
- Product number
- W327204
- Product name
- 2,5-Dimethylpyrazine
- Purity
- ≥98%, FG
- Packaging
- 1kg
- Price
- $372
- Updated
- 2024/03/01
- Product number
- 175420
- Product name
- 2,5-Dimethylpyrazine
- Purity
- 98%
- Packaging
- 5g
- Price
- $41.8
- Updated
- 2024/03/01
- Product number
- 84233
- Product name
- 2,5-Dimethylpyrazine
- Purity
- analytical standard
- Packaging
- 1ml
- Price
- $69.7
- Updated
- 2022/05/15
2,5-Dimethyl pyrazine Chemical Properties,Usage,Production
Chemical Properties
clear colorless to pale yellow liquid
Chemical Properties
2,5-Dimethylpyrazine has a characteristic odor of earthy, potato-like odor.
Occurrence
Reported to be present in bakery products, roasted barley, cocoa products, roasted coffee, dairy products, pork, peanuts, pecans, filberts, popcorn, potato products, rum and whiskey, soy products; a volatile component in roasted filberts and in potato chips; reportedly identified in the fat of cooked beef; also reported found in toasted off-flavors. Also reported in cheeses, butter, boiled eggs, grilled beef, tea, barley, oats, oatmeal, soybeans, heated beans, kohlrabi, shrimp and mushrooms. Also reported found in coffee, potato chips and shrimp
Uses
2,5-Dimethylpyrazine is used as a reagent in the synthesis of bone-targeted proteasome inhibitors for multiple myeloma (MM). 2,5-Dimethylpyrazine is also used in the preparation of 3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine (M295340); a degredation product of Clavulanic Acid (C563750) which is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.
Uses
2,5-Dimethyl pyrazine is used for blending food, nuts and beverage flavors.
Application
2,5-Dimethyl pyrazine is held chiefly responsible for the typical flavor of Potato Chips (oil-fried, thin-sliced Potato). It has therefore been manufactured synthetically and is used in the reconditioning of commercial products, such as Potato Chips and the packaging material for same, and also for reconditioning of "instant" coffee.
Definition
ChEBI: 2,5-Dimethylpyrazine is a member of pyrazines.
Preparation
By the interaction of acrolein and ammonia when heated in glycerol in the presence of ammonium salts; by self-condensation of aminoacetone, followed by oxidation with mercury chloride.
Aroma threshold values
Detection: 80 ppb to 1.8 ppm
Taste threshold values
Taste characteristics at 7.5 ppm: musty, potato, cocoa and nutty with a fatty and oily nuance
General Description
2,5-Dimethylpyrazine is a pyrazine compound that is mainly formed in food products such as cooked rice or roasted peanuts due to the Maillard reaction between sugars and proteins during cooking or roasting process.
Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx
Purification Methods
Purify it via its picrate (m 150o) which is decomposed with a base (e,g, KOH) and distilled. [Wiggins and Wise J Chem Soc 4780 1956]. [Beilstein 23/5 V 403.]
2,5-Dimethyl pyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,5-Dimethyl pyrazine manufacturers
- Product
- 2,5-Dimethyl pyrazine 123-32-0
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-31
- Product
- 2,5-Dimethyl pyrazine 123-32-0
- Price
- US $10.00-7.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 10 tons
- Release date
- 2024-06-05
- Product
- 2,5-Dimethyl pyrazine 123-32-0
- Price
- US $10.00-7.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 10 tons
- Release date
- 2024-06-13