N-Methyl-N-(trimethylsilyl)trifluoroacetamide

Product Name: N-Methyl-N-(trimethylsilyl)trifluoroacetamide
CAS No.: 24589-78-4
Chemical Name: N-Methyl-N-(trimethylsilyl)trifluoroacetamide
Synonyms: MSTFA;DK232;MSTFA MSTFA;MSTFA Reagent;MSTFA ACTIVATED I;MSTFA+TMCS (99:1);MSTFA ACTIVATED II;MSTFA ACTIVATED III;MSTFA with 1 % TMCS;N-Methyl-N-(trimethy
CBNumber: CB0161574
Molecular Formula: C6H12F3NOSi
Formula Weight: 199.25
MOL File: 24589-78-4.mol

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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Property

Melting point:: 98-100°C
Boiling point:: 130132°C
Density: 1.075 g/mL at 25 °C(lit.)
vapor density: >1 (vs air)
vapor pressure: 8.8 mm Hg ( 27 °C)
refractive index: n20/D 1.383
Flash point:: 77 °F
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
pka: -1.34±0.70(Predicted)
form: Liquid
color: Clear colorless to light yellow
Specific Gravity: 1.076
Water Solubility: reacts
Sensitive: Moisture Sensitive
Hydrolytic Sensitivity: 7: reacts slowly with moisture/water
BRN: 1941550
InChIKey: MSPCIZMDDUQPGJ-UHFFFAOYSA-N
CAS DataBase Reference: 24589-78-4(CAS DataBase Reference)
EPA Substance Registry System: Acetamide, 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)- (24589-78-4)

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Safety

Hazard Codes: Xi,F,T,N
Risk Statements: 10-36/37/38-61-50/53-51/53
Safety Statements: 26-36-37/39-16-45-53-61
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
RTECS: AC9800000
F: 10-21
Hazard Note: Flammable
TSCA: T
HazardClass: 3
PackingGroup: III
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.41102
Product name: N-Methyl-N-trimethylsilyl-trifluoroacetamide
Purity: for synthesis
Packaging: 2ml
Price: $74.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.41102
Product name: N-Methyl-N-trimethylsilyl-trifluoroacetamide
Purity: for synthesis
Packaging: 5ml
Price: $99.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: M-132
Product name: MSTFA Reagent
Purity: ampule of 10 × 1.2?mL, analytical standard, Cerilliant?
Packaging: 10x1.2mL
Price: $144
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.41102
Product name: N-Methyl-N-trimethylsilyl-trifluoroacetamide
Purity: for synthesis
Packaging: 25mL
Price: $283
Updated: 2024/03/01

Sigma-Aldrich

Product number: 69478
Product name: N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane
Purity: for GC derivatization, LiChropur?
Packaging: 1mL
Price: $57.2
Updated: 2024/03/01

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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to light yellow liquid

Uses

A new metabolite of Famprofazone in humans.

Uses

N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.

Definition

ChEBI: An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a trimethylsilyl group. N-methyl-N-(trimethylsilyl)trifluoroacetamide is a derivat sation agent used in gas chromatography/mass spectrometry applications.

General Description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a derivatizing reagent. It can be used as alternatives to diazomethane.

Purification Methods

Fractionate the amide through a 40mm Vigreux column (p 11). Usually it contains ca 1% of methyl trifluoroacetamide and 1% of other impurities which can be removed by gas chromatography or fractionating using a spinning band column. [Donike J Chromatogr 42 103 1969, Donike J Chromatogr 103 91 1975, Beilstein 4 IV 4011.]

N-Methyl-N-(trimethylsilyl)trifluoroacetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Suppliers

Americas 1 Belgium 2 Canada 2 China 172 Europe 1 France 2 Germany 9 India 17 Italy 1 Japan 5 Norway 1 Singapore 1 Slovakia 1 Switzerland 3 United Kingdom 11 United States 54 Global 283

Pharmorgana Gmbh

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Country: Germany
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Advantage: 58

Alfa Aesar, Thermo Fisher Scientific

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Merck Millipore

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Country: Germany
ProdList: 2008
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CHEMOS GmbH & Co. KG

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Email: chemos@chemos.de
Country: Germany
ProdList: 6727
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ABCR GmbH & CO. KG

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Country: Germany
ProdList: 6831
Advantage: 75

AppliChem GmbH

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ProdList: 968
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Service Chemical Inc.

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Country: Germany
ProdList: 6350
Advantage: 71

Merck Schuchardt OHG

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Email: schuchardt-vertrieb@merck.de
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ProdList: 5827
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AppliChem GmbH

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Country: Germany
ProdList: 1607
Advantage: 74

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View Lastest Price from N-Methyl-N-(trimethylsilyl)trifluoroacetamide manufacturers

Shandong Deshang Chemical Co., Ltd.

Product: N-Methyl-N-(trimethylsilyl)trifluoroacetamide 24589-78-4
Price: US $5.90-3.20/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 tons
Release date: 2024-06-25

Hebei Chuanghai Biotechnology Co,.LTD

Product: N-Methyl-N- (trimethylsilyl) Trifluoroacetamide 24589-78-4
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-13

Hebei Fengjia New Material Co., Ltd

Product: N-Methyl-N-(trimethylsilyl)trifluoroacetamide 24589-78-4
Price: US $6.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2024-08-16

24589-78-4, N-Methyl-N-(trimethylsilyl)trifluoroacetamideRelated Search:

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