ChemicalBook > CAS DataBase List > N-Methyl-N-(trimethylsilyl)trifluoroacetamide
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
- Product Name
- N-Methyl-N-(trimethylsilyl)trifluoroacetamide
- CAS No.
- 24589-78-4
- Chemical Name
- N-Methyl-N-(trimethylsilyl)trifluoroacetamide
- Synonyms
- MSTFA;DK232;MSTFA MSTFA;MSTFA Reagent;MSTFA ACTIVATED I;MSTFA+TMCS (99:1);MSTFA ACTIVATED II;MSTFA ACTIVATED III;MSTFA with 1 % TMCS;N-Methyl-N-(trimethy
- CBNumber
- CB0161574
- Molecular Formula
- C6H12F3NOSi
- Formula Weight
- 199.25
- MOL File
- 24589-78-4.mol
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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Property
- Melting point:
- 98-100°C
- Boiling point:
- 130132°C
- Density
- 1.075 g/mL at 25 °C(lit.)
- vapor density
- >1 (vs air)
- vapor pressure
- 8.8 mm Hg ( 27 °C)
- refractive index
- n20/D 1.383
- Flash point:
- 77 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- pka
- -1.34±0.70(Predicted)
- form
- Liquid
- color
- Clear colorless to light yellow
- Specific Gravity
- 1.076
- Water Solubility
- reacts
- Sensitive
- Moisture Sensitive
- Hydrolytic Sensitivity
- 7: reacts slowly with moisture/water
- BRN
- 1941550
- InChIKey
- MSPCIZMDDUQPGJ-UHFFFAOYSA-N
- CAS DataBase Reference
- 24589-78-4(CAS DataBase Reference)
- EPA Substance Registry System
- Acetamide, 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)- (24589-78-4)
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Safety
- Hazard Codes
- Xi,F,T,N
- Risk Statements
- 10-36/37/38-61-50/53-51/53
- Safety Statements
- 26-36-37/39-16-45-53-61
- RIDADR
- UN 1993 3/PG 3
- WGK Germany
- 3
- RTECS
- AC9800000
- F
- 10-21
- Hazard Note
- Flammable
- TSCA
- T
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29319090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 8.41102
- Product name
- N-Methyl-N-trimethylsilyl-trifluoroacetamide
- Purity
- for synthesis
- Packaging
- 2ml
- Price
- $74.4
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 8.41102
- Product name
- N-Methyl-N-trimethylsilyl-trifluoroacetamide
- Purity
- for synthesis
- Packaging
- 5ml
- Price
- $99.8
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- M-132
- Product name
- MSTFA Reagent
- Purity
- ampule of 10 × 1.2?mL, analytical standard, Cerilliant?
- Packaging
- 10x1.2mL
- Price
- $144
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 8.41102
- Product name
- N-Methyl-N-trimethylsilyl-trifluoroacetamide
- Purity
- for synthesis
- Packaging
- 25mL
- Price
- $283
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 69478
- Product name
- N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane
- Purity
- for GC derivatization, LiChropur?
- Packaging
- 1mL
- Price
- $57.2
- Updated
- 2024/03/01
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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Chemical Properties,Usage,Production
Chemical Properties
Clear colorless to light yellow liquid
Uses
A new metabolite of Famprofazone in humans.
Uses
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.
Definition
ChEBI: An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a trimethylsilyl group. N-methyl-N-(trimethylsilyl)trifluoroacetamide is a derivat sation agent used in gas chromatography/mass spectrometry applications.
General Description
N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a derivatizing reagent. It can be used as alternatives to diazomethane.
Purification Methods
Fractionate the amide through a 40mm Vigreux column (p 11). Usually it contains ca 1% of methyl trifluoroacetamide and 1% of other impurities which can be removed by gas chromatography or fractionating using a spinning band column. [Donike J Chromatogr 42 103 1969, Donike J Chromatogr 103 91 1975, Beilstein 4 IV 4011.]
N-Methyl-N-(trimethylsilyl)trifluoroacetamide Preparation Products And Raw materials
Raw materials
Preparation Products
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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Suppliers
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View Lastest Price from N-Methyl-N-(trimethylsilyl)trifluoroacetamide manufacturers
Hebei Duling International Trade Co. LTD
- Product
- N-Methyl-N-(trimethylsilyl)trifluoroacetamide 24589-78-4
- Price
- US $16.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000 tons
- Release date
- 2023-01-15
Hebei Guanlang Biotechnology Co,.LTD
- Product
- N-Methyl-N- (trimethylsilyl) Trifluoroacetamide 24589-78-4
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2023-03-07
Henan Aochuang Chemical Co.,Ltd.
- Product
- N-Methyl-N-(trimethylsilyl)trifluoroacetamide 24589-78-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-09
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