Notoginsenoside R1

ChemicalBook > CAS DataBase List > Notoginsenoside R1

Description Uses Application

Product Name: Notoginsenoside R1
CAS No.: 80418-24-2
Chemical Name: Notoginsenoside R1
Synonyms: Sanchinoside R1;NOTOGINSENOSIDE;Sanqi glucoside R1;NOTOGINSENOSIDE R1;Notoginsenoside Fb;Notoginseng extracts;NOTOGINSENOSIDE R1(SH);Notoginseng saponin R1;Notoginsenoside R1 ,98%;Notoginseng saponin FP2
CBNumber: CB0164186
Molecular Formula: C47H80O18
Formula Weight: 933.14
MOL File: 80418-24-2.mol

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Notoginsenoside R1 Property

Melting point:: 215～217℃
Boiling point:: 1010.5±65.0 °C(Predicted)
Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: H2O: soluble1mg/mL, clear, colorless
pka: 12.85±0.70(Predicted)
form: powder
color: white to off-white
InChIKey: LLPWNQMSUYAGQI-OOSPGMBYSA-N
LogP: 1.354 (est)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 24/25
WGK Germany: 3
HS Code: 29389090
Hazardous Substances Data: 80418-24-2(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N3915
Product name: Notoginsenoside R1
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $140
Updated: 2024/03/01

Sigma-Aldrich

Product number: N3915
Product name: Notoginsenoside R1
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $1020
Updated: 2023/06/20

TCI Chemical

Product number: N1129
Product name: Notoginsenoside R1
Purity: >98.0%(HPLC)
Packaging: 50mg
Price: $141
Updated: 2024/03/01

TCI Chemical

Product number: N1129
Product name: Notoginsenoside R1
Purity: >98.0%(HPLC)
Packaging: 10mg
Price: $95
Updated: 2022/04/27

Cayman Chemical

Product number: 29691
Product name: Notoginsenoside R1
Packaging: 5mg
Price: $72
Updated: 2024/03/01

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Notoginsenoside R1 Chemical Properties,Usage,Production

Description

Notoginsenoside R1 is a ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a disaccharide derivative, a ginsenoside, a tetracyclic triterpenoid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

Uses

Notoginsenoside R1 is an active ingredient isolated from Panax notoginseng that induces tissue-type plasminogen activator synthesis in cultured human umbilical vein endothelial cells.

Application

Notoginsenoside R1 has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an apoptosis inducer and a phytoestrogen.

Uses

Notoginsenoside R1 acts as an anti-inflammatory agent, inhibiting TNF-α induced PAI-1 production in aortic smooth muscle cells in humans.

Definition

ChEBI: Notoginsenoside R1 is a ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an apoptosis inducer and a phytoestrogen. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a disaccharide derivative, a ginsenoside, a tetracyclic triterpenoid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

Notoginsenoside R1 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Notoginsenoside R1 manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Notoginsenoside R1 80418-24-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 80% HPLC
Supply Ability: 1000KG
Release date: 2022-09-22

BINBO BIOLOGICAL CO.,LTD

Product: Notoginsenoside R1 80418-24-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 75% 80% 90% 99%
Supply Ability: 1000 kg
Release date: 2024-04-23

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: Notoginsenoside R1 80418-24-2
Price: US $15.00/kg
Min. Order: 1kg
Purity: 99.912%
Supply Ability: 10ton
Release date: 2024-04-22

80418-24-2, Notoginsenoside R1Related Search:

PANAX NOTOGINSENOSIDES Saponin Ginseng extract Dioscin Escin TRIBULOSIDE Notoginsenoside Ft1 Notoginseng triterpenes Notoginsenoside R2 20(R)-Notoginsenoside R2 Notoginsenoside FP2 NotoginsenosideFc GYPENOSIDE IX Notoginsenoside Fa Notoginsenoside S 3,3,5,5-TETRAMETHYLCYCLOHEXANOL GINSENOSIDEF1 Ginsenoside Rg1

(3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-β-D-glucopyranoside

Notoginsenoside Fb

NOTOGINSENOSIDE R1

NOTOGINSENOSIDE R1(SH)

NOTOGINSENOSIDE

glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl2-O-β-D-xylopyranosyl-

Sanchinoside R1

Notoginsenoside R1，Sanchinoside R1

Notoginsenoside R1 ,98%

Notoginsenoside R1, 98%, from Panax notoginseng (Burk.)F.H.Chen

Sanqi glucoside R1

2-[2-[6-[[4,5-dihydroxy-6-(hydroxymethyl)-3-methyl-2-oxanyl]oxy]-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2

Notoginseng extracts

Notoginsenoside R1 Standard

β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-

(3beta,6alpha,12beta)-20-(beta-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-beta-D-Xylopyranosyl-beta-D-glucopyranoside

(2S,3R,4S,5S,6R)-2-[(2S)-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-6-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

TIANFU-CHEM Notoginsenoside R1

Panax notoginseng saponin R1

(2S,3R,4S,5S,6R)-2-(((S)-2-((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-6-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,12-dihydroxy-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methylhept-5-en-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Notoginseng saponin R1

Notoginseng saponin FP2

80418-24-2

C47H80O18

chemical reagent

Inhibitors

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract