Description Uses Application
ChemicalBook > CAS DataBase List > Notoginsenoside R1

Notoginsenoside R1

Description Uses Application
Product Name
Notoginsenoside R1
CAS No.
80418-24-2
Chemical Name
Notoginsenoside R1
Synonyms
Sanchinoside R1;NOTOGINSENOSIDE;Sanqi glucoside R1;NOTOGINSENOSIDE R1;Notoginsenoside Fb;Notoginseng extracts;Notoginsenoside R1-RM;NOTOGINSENOSIDE R1(SH);Notoginseng saponin R1;Notoginsenoside R1 ,98%
CBNumber
CB0164186
Molecular Formula
C47H80O18
Formula Weight
933.14
MOL File
80418-24-2.mol
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Notoginsenoside R1 Property

Melting point:
215~217℃
Boiling point:
1010.5±65.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: soluble1mg/mL, clear, colorless
pka
12.85±0.70(Predicted)
form 
powder
color 
white to off-white
InChIKey
LLPWNQMSUYAGQI-OOSPGMBYSA-N
LogP
1.354 (est)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
24/25
WGK Germany 
3
HS Code 
29389090
Hazardous Substances Data
80418-24-2(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N3915
Product name
Notoginsenoside R1
Purity
≥98% (HPLC)
Packaging
10mg
Price
$140
Updated
2024/03/01
Sigma-Aldrich
Product number
N3915
Product name
Notoginsenoside R1
Purity
≥98% (HPLC)
Packaging
50mg
Price
$1020
Updated
2023/06/20
TCI Chemical
Product number
N1129
Product name
Notoginsenoside R1
Purity
>98.0%(HPLC)
Packaging
50mg
Price
$141
Updated
2024/03/01
TCI Chemical
Product number
N1129
Product name
Notoginsenoside R1
Purity
>98.0%(HPLC)
Packaging
10mg
Price
$95
Updated
2022/04/27
Cayman Chemical
Product number
29691
Product name
Notoginsenoside R1
Packaging
5mg
Price
$72
Updated
2024/03/01
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Notoginsenoside R1 Chemical Properties,Usage,Production

Description

Notoginsenoside R1 is a ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a disaccharide derivative, a ginsenoside, a tetracyclic triterpenoid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

Uses

Notoginsenoside R1 is an active ingredient isolated from Panax notoginseng that induces tissue-type plasminogen activator synthesis in cultured human umbilical vein endothelial cells.

Application

Notoginsenoside R1 has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an apoptosis inducer and a phytoestrogen. 

Uses

Notoginsenoside R1 acts as an anti-inflammatory agent, inhibiting TNF-α induced PAI-1 production in aortic smooth muscle cells in humans.

Definition

ChEBI: Notoginsenoside R1 is a ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an apoptosis inducer and a phytoestrogen. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a disaccharide derivative, a ginsenoside, a tetracyclic triterpenoid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

Notoginsenoside R1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Notoginsenoside R1 Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from Notoginsenoside R1 manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
Notoginsenoside R1 80418-24-2
Price
US $0.00/KG
Min. Order
1KG
Purity
80% HPLC
Supply Ability
1000KG
Release date
2022-09-22
BINBO BIOLOGICAL CO.,LTD
Product
Notoginsenoside R1 80418-24-2
Price
US $0.00/kg
Min. Order
1kg
Purity
75% 80% 90% 99%
Supply Ability
1000 kg
Release date
2024-04-23
Wuhan Quanjinci New Material Co.,Ltd.
Product
Notoginsenoside R1 80418-24-2
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
23000000 tons
Release date
2023-11-07

80418-24-2, Notoginsenoside R1Related Search:


  • (3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-β-D-glucopyranoside
  • Notoginsenoside Fb
  • NOTOGINSENOSIDE R1
  • NOTOGINSENOSIDE R1(SH)
  • NOTOGINSENOSIDE
  • glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl2-O-β-D-xylopyranosyl-
  • Sanchinoside R1
  • Notoginsenoside R1,Sanchinoside R1
  • Notoginsenoside R1 ,98%
  • Notoginsenoside R1, 98%, from Panax notoginseng (Burk.)F.H.Chen
  • Sanqi glucoside R1
  • 2-[2-[6-[[4,5-dihydroxy-6-(hydroxymethyl)-3-methyl-2-oxanyl]oxy]-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2
  • Notoginseng extracts
  • Notoginsenoside R1 Standard
  • β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-
  • (3beta,6alpha,12beta)-20-(beta-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-beta-D-Xylopyranosyl-beta-D-glucopyranoside
  • (2S,3R,4S,5S,6R)-2-[(2S)-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-6-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
  • TIANFU-CHEM Notoginsenoside R1
  • Panax notoginseng saponin R1
  • (2S,3R,4S,5S,6R)-2-(((S)-2-((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-6-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,12-dihydroxy-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methylhept-5-en-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • Notoginseng saponin R1
  • Notoginseng saponin FP2
  • Panax Notoginseng Saponins, PNS
  • Notoginsenoside R1-RM
  • 80418-24-2
  • C47H80O18
  • chemical reagent
  • Inhibitors
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract