Alpha-D-Lactose monohydrate
- Product Name
- Alpha-D-Lactose monohydrate
- CAS No.
- 5989-81-1
- Chemical Name
- Alpha-D-Lactose monohydrate
- Synonyms
- LACTOSE MONOHYDRATE;α-Lactose;MILK SUGAR;ALPHA-LACTOSE MONOHYDRATE;ALPHA-D-LACTOSE;α-D-Lactose monohydrate;A-LACTOSE;Pharmatose 150M;ALPHA-LACTOSE MONOHY;A-LACTOSE MONOHYDRATE
- CBNumber
- CB0177832
- Molecular Formula
- C12H24O12
- Formula Weight
- 360.31
- MOL File
- 5989-81-1.mol
Alpha-D-Lactose monohydrate Property
- Melting point:
- 219 °C
- Boiling point:
- 412.35°C (rough estimate)
- alpha
- [α]D20+52.2～+52.8°
- Density
- 1,53 g/cm3
- refractive index
- 1.6480 (estimate)
- RTECS
- OD9625000
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- H2O: soluble1M, clear, colorless
- form
- Solid
- color
- White to Off-White
- PH
- pH (50g/l, 25℃) : 4.0～6.0
- Water Solubility
- Soluble in water.
- Stability:
- Hygroscopic
- InChIKey
- WSVLPVUVIUVCRA-KPKNDVKVSA-N
- CAS DataBase Reference
- 5989-81-1(CAS DataBase Reference)
- EPA Substance Registry System
- .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, hydrate (1:1) (5989-81-1)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 40-36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 17021100
N-Bromosuccinimide Price
- Product number
- L2643
- Product name
- α-Lactose monohydrate
- Purity
- suitable for cell culture, BioReagent
- Packaging
- 5kg
- Price
- $163
- Updated
- 2024/03/01
- Product number
- 47287-U
- Product name
- Lactose Monohydrate
- Purity
- analyticalstandard
- Packaging
- 1kit
- Price
- $24.8
- Updated
- 2024/03/01
- Product number
- A11074
- Product name
- alpha-D-Lactose monohydrate
- Packaging
- 250g
- Price
- $23.65
- Updated
- 2024/03/01
- Product number
- A11074
- Product name
- alpha-D-Lactose monohydrate
- Packaging
- 1000g
- Price
- $56.65
- Updated
- 2024/03/01
- Product number
- 036218
- Product name
- alpha-D-Lactose monohydrate
- Purity
- ACS
- Packaging
- 500g
- Price
- $46.3
- Updated
- 2023/06/20
Alpha-D-Lactose monohydrate Chemical Properties,Usage,Production
Chemical Properties
White powder
Chemical Properties
Lactose occurs as white to off-white crystalline particles or powder. It is odorless and slightly sweet-tasting. Spray-dried directcompression grades of lactose are generally composed of 80–90% specially prepared pure a-lactose monohydrate along with 10–20% of amorphous lactose.
Uses
alpha-D-Lactose monohydrate is used as a carrier and stabiliser of aromas, pharmaceutical products, Food industry.
Production Methods
A suspension of a-lactose monohydrate crystals in a lactose solution is atomized and dried in a spray drier. Approximately 10–20% of the total amount of lactose is in solution and the remaining 80–90% is present in the crystalline form. The spray-drying process predominantly produces spherical particles. The compactibility of the material and its flow characteristics are a function of the primary particle size of the lactose monohydrate and the amount of amorphous lactose.
Definition
A sugar that occurs in many plants. It is extracted commercially from sugar cane and sugar beet. Sucrose is a disaccharide formed from a glucose unit and a fructose unit. It is hydrolyzed to a mixture of fructose and glucose by the enzyme invertase. Since this mixture has a different optical rotation (levorotatory) than the original sucrose, the mixture is called invert sugar.
Pharmaceutical Applications
Spray-dried lactose is widely used as a binder, filler-binder, and flow aid in direct compression tableting.
Biochem/physiol Actions
alpha-Lactose is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk. It is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns. The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.
Safety
Lactose is widely used in pharmaceutical formulations as a diluent
in oral capsule and tablet formulations. It may also be used in
intravenous injections.
Adverse reactions to lactose are largely due to lactose intolerance,
which occurs in individuals with a deficiency of the enzyme
lactase.
storage
Spray-dried lactose should be stored in a well-closed container in a cool, dry place.
Incompatibilities
Lactose is a reducing sugar. The amorphous lactose, which is the most reactive form of lactose present in spray-dried lactose, will interact more readily than conventional crystalline grades. Typical reactions include the Maillard reaction with either primary or secondary amines.
Alpha-D-Lactose monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Alpha-D-Lactose monohydrate Suppliers
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View Lastest Price from Alpha-D-Lactose monohydrate manufacturers
- Product
- Alpha-D-Lactose monohydrate 5989-81-1
- Price
- US $3.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000
- Release date
- 2024-08-16
- Product
- Alpha-D-Lactose monohydrate 5989-81-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2021-11-11
- Product
- Alpha-D-Lactose monohydrate 5989-81-1
- Price
- US $8.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09