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2-Amino-4-phenylbutane

Product Name
2-Amino-4-phenylbutane
CAS No.
22374-89-6
Chemical Name
2-Amino-4-phenylbutane
Synonyms
1-Methyl-Phenylpropylamine;1-Methyl-3-Benzenepropanamine;NSC 115524;AURORA KA-7110;DL-AMPHETAMINE;(+/-)-AMPHETAMINE;LabetalolImpurity6;sopropylbenzylamine;1-Phenyl-3-butanamine;4-Phenyl-2-butanamine
CBNumber
CB0191896
Molecular Formula
C10H15N
Formula Weight
149.24
MOL File
22374-89-6.mol
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2-Amino-4-phenylbutane Property

Melting point:
-50°C
Boiling point:
228-232 °C (lit.)
Density 
0.922 g/mL at 25 °C (lit.)
vapor pressure 
10.146Pa at 25℃
refractive index 
n20/D 1.514(lit.)
Flash point:
208 °F
storage temp. 
−20°C
solubility 
soluble in Chloroform, Ethyl Acetate
form 
liquid
pka
pKa 10.0 (Uncertain)
Specific Gravity
0.922
color 
Clear
PH
11.6 (10g/l, H2O, 20℃)
Water Solubility 
8.5 g/L (20 ºC)
Sensitive 
Air Sensitive
BRN 
2413110
LogP
2.12
CAS DataBase Reference
22374-89-6(CAS DataBase Reference)
NIST Chemistry Reference
Benzenepropanamine, «alpha»-methyl-(22374-89-6)
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Safety

Hazard Codes 
C,Xi,T,F
Risk Statements 
34-22-39/23/24/25-23/24/25-11
Safety Statements 
26-36/37/39-45-28A-36/37
RIDADR 
UN 2735 8/PG 3
WGK Germany 
2
RTECS 
UI3920000
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
III
HS Code 
29214980
Toxicity
LD orl-rat: >600 mg/kg AEPPAE 195,647,1940
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M70533
Product name
1-Methyl-3-phenylpropylamine
Purity
98%
Packaging
25g
Price
$143
Updated
2024/03/01
Alfa Aesar
Product number
A18804
Product name
3-Amino-1-phenylbutane, 98%
Packaging
100g
Price
$162
Updated
2021/12/16
Alfa Aesar
Product number
A18804
Product name
3-Amino-1-phenylbutane, 98%
Packaging
500g
Price
$601
Updated
2021/12/16
TRC
Product number
M325470
Product name
1-Methyl-3-phenylpropylamine
Packaging
10g
Price
$50
Updated
2021/12/16
TRC
Product number
M325470
Product name
1-Methyl-3-phenylpropylamine
Packaging
100g
Price
$235
Updated
2021/12/16
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2-Amino-4-phenylbutane Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

2-Amino-4-phenylbutane is used in the synthesis of N-substituted derivatives of (1-methyl-3- phenylpropyl)amine.

Biological Functions

Amphetamine is an indirectly acting adrenomimetic amine that depends for its action on the release of norepinephrine from noradrenergic nerves. Its pharmacological effects are similar to those of ephedrine; however, its CNS stimulant activity is somewhat greater. Both systolic and diastolic blood pressures are increased by oral dosing with amphetamine. The heart rate is frequently slowed reflexively. Cardiac output may remain unchanged in the low- and moderate-dose range. The therapeutic uses of amphetamine are based on its ability to stimulate the CNS. The D-isomer (dextroamphetamine) is three to four times as potent as the L-isomer in producing CNS effects. It has been used in the treatment of obesity because of its anorexic effect, although tolerance to this effect develops rapidly. It prevents or overcomes fatigue and has been used as a CNS stimulant. Amphetamine is no longer recommended for these uses because of its potential for abuse. Amphetamine is useful in certain cases of narcolepsy or minimal brain dysfunction.

Flammability and Explosibility

Not classified

Safety Profile

A poison by intraperitoneal and parenteral route. Moderately toxic by ingestion.When heated to decomposition it emits toxic vapors of NOx.

Synthesis

Amphetamine is prepared by treating phenylacetone with formic acid and ammonia under the Leuckart-Wallach conditions .

2-Amino-4-phenylbutane Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-4-phenylbutane Suppliers

Americas 1 Austria 1 Belgium 2 Canada 2 China 237 Europe 3 Germany 6 India 16 Italy 1 Japan 2 Slovakia 1 South Korea 1 Switzerland 3 United Kingdom 6 United States 30 Global 312
MDP ChemControl Ltd.
Tel
--
Fax
--
Email
chemcontrol@nextra.sk
Country
Slovakia
ProdList
6700
Advantage
60
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View Lastest Price from 2-Amino-4-phenylbutane manufacturers

Dorne Chemical Technology co. LTD
Product
2-Amino-4-phenylbutane 22374-89-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
Hebei Miaoyin Technology Co.,Ltd
Product
2-Amino-4-phenylbutane 22374-89-6
Price
US $20.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000
Release date
2023-04-06
Hebei Dangtong Import and export Co LTD
Product
2-Amino-4-phenylbutane 22374-89-6
Price
US $2.40-2.00/Grams
Min. Order
100Grams
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-03

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