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AMASTATIN HYDROCHLORIDE

Product Name
AMASTATIN HYDROCHLORIDE
CAS No.
100938-10-1
Chemical Name
AMASTATIN HYDROCHLORIDE
Synonyms
AMASTATIN;AMASTATIN HCL;AMASTATIN HYDROCHLORIDE;AMASTATIN HYDROCHLORIDE HYDRATE;H-(2S,3R)-AHMH-VAL-VAL-ASP-OH HCL;Amastatin hydrate hydrochloride;4-formylphenyl-O-β-d-allopyranoside;N((2S 3R)3-AMINO-2-HXY-5-ME.HEXANOYL)-L&;Amastatinhydrochloridebiochemikasynthetic;(2S,3R)-[3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP-OH HCL
CBNumber
CB0194817
Molecular Formula
C21H39ClN4O8
Formula Weight
511.01
MOL File
100938-10-1.mol
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AMASTATIN HYDROCHLORIDE Property

Melting point:
202-205 °C
storage temp. 
-20°C
solubility 
methanol: 5 mg/mL, clear, colorless
form 
White to off-white powder.
color 
White to off-white
BRN 
8888370
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Safety

WGK Germany 
3
F 
10
HS Code 
2924190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A1276
Product name
Amastatin hydrochloride hydrate
Purity
≥97% (HPLC)
Packaging
0.5mg
Price
$177
Updated
2024/03/01
Sigma-Aldrich
Product number
A1276
Product name
Amastatin hydrochloride hydrate
Purity
≥97% (HPLC)
Packaging
1mg
Price
$282
Updated
2024/03/01
Cayman Chemical
Product number
16719
Product name
Amastatin (hydrochloride)
Purity
≥95%
Packaging
500μg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
16719
Product name
Amastatin (hydrochloride)
Purity
≥95%
Packaging
1mg
Price
$60
Updated
2024/03/01
Sigma-Aldrich
Product number
A1276
Product name
Amastatin hydrochloride hydrate
Purity
≥97% (HPLC)
Packaging
5mg
Price
$1010
Updated
2024/03/01
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AMASTATIN HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Amastatin is a slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of human serum AP-A (glutamyl AP; IC50 = 0.54 μg/ml) but not of AP-B (arginine AP). It also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic reticulum AP 1 (Ki = 41.8 μM). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin, or thermolysin.[Cayman Chemical]

General Description

Chemical structure: peptide

Biochem/physiol Actions

It inhibits cytosolic leucine aminopeptidase (EC.3.4.11.1), microsomal aminopeptidase M (EC.3.4.11.2) and bacterial leucine aminopeptidase (EC.3.4.11.10). It is less effective against aminopeptidase A (EC 3.4.11.7), the enzyme that converts angiotensin II to angiotensin III. Potentiates the CNS effects of vasopressin and oxytocin in vivo.Effective concentration: 1-10 μM.

storage

+4°C

AMASTATIN HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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AMASTATIN HYDROCHLORIDE Suppliers

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View Lastest Price from AMASTATIN HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
AMASTATIN HYDROCHLORIDE 100938-10-1
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

100938-10-1, AMASTATIN HYDROCHLORIDERelated Search:

N-(2-AMINOETHYL)-L-ASPARTIC ACID GLYCYLGLYCINE HYDROCHLORIDE L-Homoserine L-Aspartic acid hydrochloride D-Leucinol H-VAL-NH2 HCL 1,3-Diamino-2-propanol H-BETA-ALA-NH2 HCL (R)-HOMO-BETA-ALANINE HYDROCHLORIDE H-VAL-ASP-OH AC-VAL-NHME H-ALA-ALA-NH2 HCL AC-VAD-CHO (S)-(-)-LACTAMIDE H-VAL-BETA-ALA-OH BETA-HOMOALANINE HYDROCHLORIDE AMASTATIN,AMASTATIN, STREPTOMYCES SPECIES H-ALA-VAL-NH2 HCL

  • [(2S,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP HYDROCHLORIDE
  • (2S,3R)-[3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP-OH HCL
  • AMASTATIN
  • AMASTATIN HCL
  • AMASTATIN HYDROCHLORIDE
  • AMASTATIN HYDROCHLORIDE HYDRATE
  • H-(2S,3R)-AHMH-VAL-VAL-ASP-OH HCL
  • N((2S 3R)3-AMINO-2-HXY-5-ME.HEXANOYL)-L&
  • Amastatinhydrochloridebiochemikasynthetic
  • (2s,3r)-3-amino-2-hydroxy-5-methylhexanoyl-val-val-asp hydrochloride hydrate
  • (Amino-2-hydroxy-5-methyl-hexanoyl)-L-valyl-L-valyl-L-aspartic acid hydrochloride salt
  • (2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl-Val-Val-Asp hydrate hydrochloride
  • Amastatin hydrate hydrochloride
  • L-Aspartic acid,N-[(2S,3R)-3-amino-2-hydroxy-5-methyl-1-oxohexyl]-L-valyl-L-valyl-,monohydrochloride (9CI)
  • 4-formylphenyl-O-β-d-allopyranoside
  • 100938-10-1
  • C21H38N4O8HCl
  • C21H38N4O8HClxH2O
  • C21H38N4O8ClH
  • BioChemical
  • Antibiotics
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  • peptides
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