ChemicalBook > CAS DataBase List > (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

Product Name
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
CAS No.
291775-59-2
Chemical Name
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
Synonyms
LED-C-3;Ledipasvir INT 2;Ledipasvir Impurity 14;(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic a;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-2-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%;(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 291775-59-2;(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid ISO 9001：2015 REACH
CBNumber
CB02098856
Molecular Formula
C12H19NO4
Formula Weight
241.28
MOL File
291775-59-2.mol
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(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Property

Melting point:
147-152 °C
Boiling point:
371.0±25.0 °C(Predicted)
Density 
1.232±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
4.05±0.20(Predicted)
optical activity
[α]22/D -170±10°, c = 1 in chloroform
InChIKey
IFAMSTPTNRJBRG-YIZRAAEISA-N
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Safety

Hazard Codes 
Xi,N
Risk Statements 
61-36/37/38
Safety Statements 
53-26-61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H360May damage fertility or the unborn child

H400Very toxic to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
695491
Product name
(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
Purity
97%
Packaging
250mg
Price
$45.6
Updated
2024/03/01
Sigma-Aldrich
Product number
695491
Product name
(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
Purity
97%
Packaging
1g
Price
$318
Updated
2024/03/01
TRC
Product number
B694100
Product name
(1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylicAcid
Packaging
5g
Price
$745
Updated
2021/12/16
ChemScene
Product number
CS-M2578
Product name
2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylicacid,2-(1,1-dimethylethyl)ester,(1R,3S,4S)-
Purity
99.11%
Packaging
25g
Price
$453
Updated
2021/12/16
ChemScene
Product number
CS-M2578
Product name
2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylicacid,2-(1,1-dimethylethyl)ester,(1R,3S,4S)-
Purity
99.11%
Packaging
10g
Price
$256
Updated
2021/12/16
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(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Chemical Properties,Usage,Production

Uses

(1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-??daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants.

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Suppliers

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View Lastest Price from (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 291775-59-2
Price
US $5.00/kg
Min. Order
1kg
Purity
99.92%
Supply Ability
50000tons
Release date
2024-04-24
Henan Bao Enluo International TradeCo.，LTD
Product
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 291775-59-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500t/month
Release date
2023-08-17
Hebei Mojin Biotechnology Co., Ltd
Product
(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 291775-59-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-14

291775-59-2, (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acidRelated Search:

(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate (1S)-1-(diphenylphosphino)-2-[(1R)-1-(diphenylphosphino)ethyl]-Ferrocene (S)-1-[(R)-2-(DI-TERT.-BUTYLPHOSPHINO)FERROCENYL]ETHYLBIS(2-METHYLPHENYL)PHOSPHI (1R,2R)-(-)-1,2-Diaminocyclohexane (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride Ledipasvir ledipasvir interMediate ledipasvir interMediate 2,7-DibroMo-9,9-difluoro-9H-fluorene (S)-2-((Methoxycarbonyl)aMino)-3-Methylbutanoic acid 2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-(6-broMo-1H-benziMidazol-2-yl)-, 1,1-diMethylethyl ester,(1R,3S,4S)- (S)-5-BOC-5-AZASPIRO[2.4]HEPTANE-6-CARBOXYLIC ACID 1-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-chloro-Ethanone ledipasvir interMediate (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid

  • (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
  • (1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
  • (1R,3S,4S)-N-(Tert-butoxycarbonyl)-2-azabicyclo-[2.2.1]-heptane-3-carboxylic acid
  • (1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%
  • 2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 2-(1,1-diMethylethyl) ester, (1R,3S,4S)-
  • (1R,3S,4S)-3-[(2-methylpropoxy)carbonyl]-2-azabicyclo[2.2.1]heptane-2-carboxylic acid
  • Ledipasvir INT 2
  • Ledipasvir Impurity 14
  • LED-C-3
  • (1R,3S,4S)-2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylic acid 2-tert-butyl ester
  • (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid ISO 9001：2015 REACH
  • (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 291775-59-2
  • (1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic a
  • 2-(1,1-Dimethylethyl) (1R,3S,4S)-2-azabicyclo[2.2.1]heptane-2,3-dicarboxylate
  • (1R,3S,4S)-2-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid
  • 291775-59-2
  • Pharmaceuticalintermediates