N-BOC-3-Aminopiperidine

Product Name: N-BOC-3-Aminopiperidine
CAS No.: 184637-48-7
Chemical Name: N-BOC-3-Aminopiperidine
Synonyms: TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE;1-BOC-3-AMINOPIPERIDINE;Azacycloheptane, 3-amino-1-t-butoxycarbonyl-;N-BOC-3-AMinopiperid;3-AMINO-1-N-BOC-PIPERIDINE;3-Amino-1-Boc-piperidine,97%;N-BOC-3-Aminopiperidine USP/EP/BP;1-BOC-3-AMINOPIPERIDINE HYDROCHLORIDE;3-AMINO-1-TERTBUTOXYCARBONYL-PIPERIDINE;3-amino-1-piperidinecarboxylic acid tert-butyl ester
CBNumber: CB0211321
Molecular Formula: C10H20N2O2
Formula Weight: 200.28
MOL File: 184637-48-7.mol

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N-BOC-3-Aminopiperidine Property

Melting point:: 181-182°C
Boiling point:: 277.3±33.0 °C(Predicted)
Density: 1.02
refractive index: 1.4710-1.4750
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: clear liquid
pka: 10.35±0.20(Predicted)
color: Colorless to Light yellow
optical activity: Consistent with structure
Water Solubility: Slightly soluble in water.
Sensitive: Air Sensitive
InChI: InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3
InChIKey: AKQXKEBCONUWCL-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCCC(N)C1
CAS DataBase Reference: 184637-48-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38-51
Safety Statements: 26-39-37
HazardClass: IRRITANT
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2314
Product name: 3-Amino-1-tert-butoxycarbonylpiperidine
Purity: >97.0%(GC)(T)
Packaging: 1g
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: A2314
Product name: 3-Amino-1-tert-butoxycarbonylpiperidine
Purity: >97.0%(GC)(T)
Packaging: 5g
Price: $107
Updated: 2025/07/31

TRC

Product number: B621143
Product name: 1-Boc-3-aminopiperidine
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Usbiological

Product number: 228677
Product name: 1-Boc-3-aminopiperidine citric acid salt
Packaging: 250mg
Price: $273
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB31217
Product name: 1-Boc-3-aminopiperidine
Packaging: 100g
Price: $290
Updated: 2021/12/16

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N-BOC-3-Aminopiperidine Chemical Properties,Usage,Production

Uses

3-Amino-1-Boc-piperidine is used as an organic chemical synthesis intermediate.

Synthesis

54012-73-6

24424-99-5

144243-24-3

184637-48-7

In a 200 mL four-necked flask equipped with a stirrer, pH sensor, and two dropping funnels, 90 g of ethanol and 10.0 g (0.1 mol) of 3-aminopiperidine were added and stirred at 10 to 15 °C. 21.8 g (0.1 mol) di-tert-butyl dicarbonate was slowly added through one dropping funnel while 17.6 g (0.11 mol) 25% aqueous sodium hydroxide was added dropwise through the other dropping funnel, and the dropping rate was controlled to maintain the pH of the reaction system between 11.8 and 12.2. The titration process was completed in about 1 hour. Upon completion of the reaction, the composition of the reaction mixture was analyzed and confirmed to contain 6% unreacted 3-aminopiperidine, 91.5% of the target product 3-amino-1-tert-butoxycarbonylpiperidine and 1.1% of the by-product 3-tert-butoxycarbonylaminopiperidine.

References

[1] Patent: EP1460061, 2004, A1. Location in patent: Page 6-7

N-BOC-3-Aminopiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-BOC-3-Aminopiperidine Suppliers

Americas 1 Canada 1 China 222 Europe 4 Germany 4 India 3 Japan 1 United Kingdom 10 United States 44 Global 290

Shaanxi Henghan New Materials Co., Ltd

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View Lastest Price from N-BOC-3-Aminopiperidine manufacturers

Shanghai CRM New Material Technology Co., LTD

Product: N-BOC-3-Aminopiperidine 184637-48-7
Price: US $10.00-15.00/g
Min. Order: 10g
Purity: 99%
Supply Ability: 10t
Release date: 2022-09-22

Zhuozhou Wenxi import and Export Co., Ltd

Product: N-BOC-3-Aminopiperidine 184637-48-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-Amino-1-tert-butoxycarbonylpiperidine 184637-48-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

184637-48-7, N-BOC-3-AminopiperidineRelated Search:

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CAS:184637-48-7

184637-48-7

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