NU1025
- Product Name
- NU1025
- CAS No.
- 90417-38-2
- Chemical Name
- NU1025
- Synonyms
- NU1025;NSC 696807;NU 1025;NU 1025;NU1025 USP/EP/BP;NU1025 (NSC 696807);PARP Inhibitor VI, NU1025;8-Hydroxy-2-methylquinazolin-4(3H);8-HYDROXY-2-METHYLQUINAZOLINE-4-ONE;8-HYDROXY-2-METHYLQUINAZOLIN-4[3H]-ONE;8-HYDROXY-2-METHYL-4(3H)-QUINAZOLINONE
- CBNumber
- CB0214872
- Molecular Formula
- C9H8N2O2
- Formula Weight
- 176.17
- MOL File
- 90417-38-2.mol
NU1025 Property
- Melting point:
- 253-258°C
- Boiling point:
- 345.4±44.0 °C(Predicted)
- Density
- 1.42
- storage temp.
- −20°C
- solubility
- DMSO: 35 mg/mL, soluble
- form
- solid
- pka
- 8.68±0.20(Predicted)
- color
- off-white
- CAS DataBase Reference
- 90417-38-2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N7287
- Product name
- NU-1025
- Purity
- ≥97% (HPLC), solid
- Packaging
- 5mg
- Price
- $210
- Updated
- 2024/03/01
- Product number
- 493800
- Product name
- PARP Inhibitor VI, NU1025
- Packaging
- 5mg
- Price
- $230
- Updated
- 2024/03/01
- Product number
- 14534
- Product name
- NU 1025
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $31
- Updated
- 2024/03/01
- Product number
- 14534
- Product name
- NU 1025
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 14534
- Product name
- NU 1025
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $341
- Updated
- 2024/03/01
NU1025 Chemical Properties,Usage,Production
Description
NU 1025 is an inhibitor of poly(ADP-
Chemical Properties
Off-White to Pale Yellow Solid
Uses
NU 1025 is an inhibitor of poly(ADP-ribose) polymerases (PARP) (IC50 = 400 nM). It enhances the cytotoxicity of γ-irradiation and certain anticancer drugs. NU 1025 is also used to study the regulation of deoxyribonucleic acid repair by PARP enzymes.[Cayman Chemical]
Uses
A potent inhibitor of poly (ADP-ribose) polymerase (PARP). Ki and IC50 values are 48 and 400 nM respectively.
Definition
ChEBI: A member of the class of quinazolines that is quinazolin-4(1H)-one substituted by a hydroxy group at position 8 and a methyl group at position 2. It has been shown to exhibit inhibitory activity against poly(ADP-ribose) polymerase.
Biological Activity
Novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP). K i and IC 50 values are 48 and 400 nM respectively.
NU1025 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from NU1025 manufacturers
- Product
- NU1025 90417-38-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98-100%
- Supply Ability
- 1000kg
- Release date
- 2018-08-20