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NU1025

Product Name
NU1025
CAS No.
90417-38-2
Chemical Name
NU1025
Synonyms
NU1025;NSC 696807;NU 1025;NU 1025;NU1025 USP/EP/BP;NU1025 (NSC 696807);PARP Inhibitor VI, NU1025;8-Hydroxy-2-methylquinazolin-4(3H);8-HYDROXY-2-METHYLQUINAZOLINE-4-ONE;8-HYDROXY-2-METHYLQUINAZOLIN-4[3H]-ONE;8-HYDROXY-2-METHYL-4(3H)-QUINAZOLINONE
CBNumber
CB0214872
Molecular Formula
C9H8N2O2
Formula Weight
176.17
MOL File
90417-38-2.mol
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NU1025 Property

Melting point:
253-258°C
Boiling point:
345.4±44.0 °C(Predicted)
Density 
1.42
storage temp. 
−20°C
solubility 
DMSO: 35 mg/mL, soluble
form 
solid
pka
8.68±0.20(Predicted)
color 
off-white
CAS DataBase Reference
90417-38-2
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
26
WGK Germany 
3
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N7287
Product name
NU-1025
Purity
≥97% (HPLC), solid
Packaging
5mg
Price
$210
Updated
2024/03/01
Sigma-Aldrich
Product number
493800
Product name
PARP Inhibitor VI, NU1025
Packaging
5mg
Price
$230
Updated
2024/03/01
Cayman Chemical
Product number
14534
Product name
NU 1025
Purity
≥98%
Packaging
1mg
Price
$31
Updated
2024/03/01
Cayman Chemical
Product number
14534
Product name
NU 1025
Purity
≥98%
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
14534
Product name
NU 1025
Purity
≥98%
Packaging
25mg
Price
$341
Updated
2024/03/01
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NU1025 Chemical Properties,Usage,Production

Description

NU 1025 is an inhibitor of poly(ADP-ribose) polymerases (PARP) (IC50 = 400 nM). It enhances the cytotoxicity of γ-irradiation and certain anticancer drugs. NU 1025 is also used to study the regulation of deoxyribonucleic acid repair by PARP enzymes.

Chemical Properties

Off-White to Pale Yellow Solid

Uses

NU 1025 is an inhibitor of poly(ADP-ribose) polymerases (PARP) (IC50 = 400 nM). It enhances the cytotoxicity of γ-irradiation and certain anticancer drugs. NU 1025 is also used to study the regulation of deoxyribonucleic acid repair by PARP enzymes.[Cayman Chemical]

Uses

A potent inhibitor of poly (ADP-ribose) polymerase (PARP). Ki and IC50 values are 48 and 400 nM respectively.

Definition

ChEBI: A member of the class of quinazolines that is quinazolin-4(1H)-one substituted by a hydroxy group at position 8 and a methyl group at position 2. It has been shown to exhibit inhibitory activity against poly(ADP-ribose) polymerase.

Biological Activity

Novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP). K i and IC 50 values are 48 and 400 nM respectively.

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NU1025 Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Chiba Pharmaceutical Science and technology Co, Ltd.
Tel
0531-81313138 13066006660
Fax
QQ: 3366077777
Email
chibapharm@foxmail.com
Country
China
ProdList
4056
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4512
Advantage
55
YouCoChem (Beijing) Chemical Technology Co., Ltd.
Tel
18800159827
Email
youcochem@163.com
Country
China
ProdList
161
Advantage
50
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
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View Lastest Price from NU1025 manufacturers

Career Henan Chemical Co
Product
NU1025 90417-38-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98-100%
Supply Ability
1000kg
Release date
2018-08-20

90417-38-2, NU1025Related Search:


  • NU1025
  • PARP Inhibitor VI, NU1025 - CAS 90417-38-2 - Calbiochem
  • NU 1025;NU 1025
  • 8-HYDROXY-2-METHYL-4(3H)-QUINAZOLINONE
  • 8-HYDROXY-2-METHYLQUINAZOLIN-4[3H]-ONE
  • 8-HYDROXY-2-METHYLQUINAZOLINE-4-ONE
  • 8-Hydroxy-2-methylquinazoline-4-one ,97%
  • 8-hydroxy-2-methyl-1H-quinazolin-4-one
  • NSC 696807
  • 4(3H)-Quinazolinone, 8-hydroxy-2-Methyl-
  • 8-hydroxy-2-methylquinazolin-4(1H)-one
  • 8-Hydroxy-2-methylquinazolin-4(3H)
  • NU1025 (NSC 696807)
  • PARP Inhibitor VI, NU1025
  • NU1025 USP/EP/BP
  • 90417-38-2
  • Kinase/Phosphatase Biology
  • Serine/Threonine Kinase Inhibitors
  • Cyclin-Dependent Kinase (CDK)
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • All Inhibitors
  • Inhibitors
  • Aromatics