ChemicalBook > CAS DataBase List > 5-Benzoyloxy-1(2H)-isoquinolinone

5-Benzoyloxy-1(2H)-isoquinolinone

Product Name
5-Benzoyloxy-1(2H)-isoquinolinone
CAS No.
370872-09-6
Chemical Name
5-Benzoyloxy-1(2H)-isoquinolinone
Synonyms
UPF 1035;PARP Inhibitor XV, UPF-1035;5-benzoyloxyisoquinolin-1-one;5-Benzoyloxy-1(2H)-isoquinolinone;1(2H)-Isoquinolinone, 5-(benzoyloxy)-;1-oxo-1,2-dihydroisoquinolin-5-yl benzoate;Benzoic Acid 1-Hydroxyisoquinolin-5-yl Ester;5-Benzoyloxy-3,4-dihydro-isoquinolinon-1(2H)- one
CBNumber
CB52502983
Molecular Formula
C16H11NO3
Formula Weight
265.26
MOL File
370872-09-6.mol
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5-Benzoyloxy-1(2H)-isoquinolinone Property

Melting point:
234-236°C
Boiling point:
575.7±50.0 °C(Predicted)
Density 
1.290±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly)
form 
Solid
pka
12.13±0.20(Predicted)
color 
Off-White to Light Pink-Orange
InChI
1S/C16H11NO3/c18-15-13-7-4-8-14(12(13)9-10-17-15)20-16(19)11-5-2-1-3-6-11/h1-10H,(H,17,18)
InChIKey
FFWUPFYTTMMSTH-UHFFFAOYSA-N
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
528825
Product name
PARP Inhibitor XV, UPF-1035 - CAS 370872-09-6 - Calbiochem
Packaging
5MG
Price
$233
Updated
2022/05/15
TRC
Product number
B208300
Product name
5-Benzoyloxy-1(2H)-isoquinolinone
Packaging
10mg
Price
$120
Updated
2021/12/16
TRC
Product number
B208300
Product name
5-Benzoyloxy-1(2H)-isoquinolinone
Packaging
50mg
Price
$545
Updated
2021/12/16
TRC
Product number
B208300
Product name
5-Benzoyloxy-1(2H)-isoquinolinone
Packaging
100mg
Price
$945
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18252
Product name
5-Benzoyloxy-1(2H)-isoquinolinone
Packaging
5mg
Price
$124.9
Updated
2021/12/16
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5-Benzoyloxy-1(2H)-isoquinolinone Chemical Properties,Usage,Production

Chemical Properties

Pale Beige Solid

Uses

A isoquinolinone derivative as PARP-1/PARP-2 inhibitors.

IC 50

PARP-1: 9 μM (IC50); PARP-2: 0.15 μM (IC50)

5-Benzoyloxy-1(2H)-isoquinolinone Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Benzoyloxy-1(2H)-isoquinolinone Suppliers

Canada 1 China 22 India 1 United Kingdom 1 Global 25
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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021-50135380
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sales@chemshuttle.com
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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+86 755 28094224
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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Energy Chemical
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Jinan Jiuli Biotechnology Co. , Ltd.
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15865264761
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486064515@qq.com
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Enzo Biochem Inc
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Enzo Biochem Inc. 13797054060
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370872-09-6, 5-Benzoyloxy-1(2H)-isoquinolinoneRelated Search:

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  • 5-Benzoyloxy-1(2H)-isoquinolinone
  • 5-Benzoyloxy-3,4-dihydro-isoquinolinon-1(2H)- one
  • Benzoic Acid 1-Hydroxyisoquinolin-5-yl Ester
  • UPF 1035
  • 5-benzoyloxyisoquinolin-1-one
  • 1(2H)-Isoquinolinone, 5-(benzoyloxy)-
  • 1-oxo-1,2-dihydroisoquinolin-5-yl benzoate
  • PARP Inhibitor XV, UPF-1035
  • 370872-09-6
  • Aromatics
  • Heterocycles
  • Inhibitors