1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE

Product Name: 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
CAS No.: 284028-90-6
Chemical Name: 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
Synonyms: DR 2313;IR 2313;SC-202756;DR2313 >=98% (HPLC);PARP Inhibitor XI, DR2313;4H-Thiopyrano[4,3-d]pyriMidin-4-one,3,5,7,8-tetrahydro-2;7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one;3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one;1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE;2-Methyl-1-sulfanyl-1H,4H,5H,7H,8H-pyrano[4,3-d]pyriMidin-4-one
CBNumber: CB9837735
Molecular Formula: C8H10N2OS
Formula Weight: 182.24
MOL File: 284028-90-6.mol

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1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE Property

Boiling point:: 349.3±52.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: H2O: >2mg/mL (warmed)
form: powder
pka: 1.54±0.20(Predicted)
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0397
Product name: DR2313
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $78.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0397
Product name: DR2313
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $337
Updated: 2022/05/15

Cayman Chemical

Product number: 21181
Product name: DR2313
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21181
Product name: DR2313
Purity: ≥98%
Packaging: 5mg
Price: $74
Updated: 2024/03/01

Cayman Chemical

Product number: 21181
Product name: DR2313
Purity: ≥98%
Packaging: 10mg
Price: $122
Updated: 2024/03/01

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1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE Chemical Properties,Usage,Production

Biological Activity

Potent, competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC 50 values are 0.20 and 0.24 μ M for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro . Brain penetrant.

1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE Suppliers

China 79 Germany 1 India 1 Switzerland 1 The Netherlands 1 United Kingdom 1 United States 14 Global 98

3B Pharmachem (Wuhan) International Co.,Ltd.

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Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
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Fax: 86 025 52714266
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EMMX Biotechnology LLC

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Shanghai EFE Biological Technology Co., Ltd.

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View Lastest Price from 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE manufacturers

Career Henan Chemical Co

Product: 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE 284028-90-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2019-12-31

284028-90-6, 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONERelated Search:

4-AMINO-1,8-NAPHTHALIMIDE 3-Aminobenzamide NU1025 4-Hydroxyquinazoline Rucaparib DPQ ABT-888 PJ-34 PF-01367338 Benzamide Minocycline hydrochloride 1,5-ISOQUINOLINEDIOL 1(2H)-Isoquinolinone, 5-aMino-, Monohydrochloride 5-Benzoyloxy-1(2H)-isoquinolinone 3-(4-CHLORO-PHENYL)-QUINOXALINE-5-CARBOXYLIC ACID AMIDE TIQ-A 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE

1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE

DR 2313

7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one

3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one

4H-Thiopyrano[4,3-d]pyriMidin-4-one,3,5,7,8-tetrahydro-2

4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE,3,5,7,8-TETRAHYDRO-2-METHYL-

SC-202756

2-Methyl-1-sulfanyl-1H,4H,5H,7H,8H-pyrano[4,3-d]pyriMidin-4-one

PARP Inhibitor XI, DR2313

IR 2313

3,5,7,8-tetrahydro-2-methyl-4h-thiopyrano(4,3-d)pyrimidin-4-one, 98%(HPLC)

DR2313 >=98% (HPLC)

284028-90-6