Description application Reference
ChemicalBook > CAS DataBase List > MOPS

MOPS

Description application Reference
Product Name
MOPS
CAS No.
1132-61-2
Chemical Name
MOPS
Synonyms
MOPS;3-(N-MORPHOLINO)PROPANESULFONIC ACID;MOPS FREE ACID;MORPHOLINOPROPANE SULFONIC ACID;3-Morpholinopropanesulfoinc Acid;4-morpholinopropanesulphonic acid;3-Morpholinopropane-1-sulfonic acid;WAS 15;MOPS,≥98%;MOPS1132-61-2
CBNumber
CB0221586
Molecular Formula
C7H15NO4S
Formula Weight
209.26
MOL File
1132-61-2.mol
More
Less

MOPS Property

Melting point:
277-282 °C
Density 
1.3168 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.6370 (estimate)
Flash point:
116 °C
storage temp. 
room temp
solubility 
H2O: 1 M at 20 °C, clear
form 
Powder/Solid
color 
White
PH
2.5-4.0 (25℃, 1M in H2O)
pka
7.2(at 25℃)
PH Range
6.5 - 7.9
Odor
Odorless
Water Solubility 
1000 g/L (20 ºC)
λmax
λ: 260 nm Amax: 0.020
λ: 280 nm Amax: 0.015
Merck 
14,6265
BRN 
1106776
Stability:
Stable. Incompatible with strong bases, strong oxidizing agents.
InChIKey
DVLFYONBTKHTER-UHFFFAOYSA-N
LogP
-2.94 at 20℃
CAS DataBase Reference
1132-61-2(CAS DataBase Reference)
EPA Substance Registry System
4-Morpholinepropanesulfonic acid (1132-61-2)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
1
RTECS 
QE9104530
TSCA 
Yes
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHG0007
Product name
MOPS
Packaging
1KIT
Price
$1191
Updated
2024/03/01
Sigma-Aldrich
Product number
M3183
Product name
MOPS
Purity
BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)
Packaging
25KG
Price
$9130
Updated
2024/03/01
Sigma-Aldrich
Product number
M1254
Product name
MOPS
Purity
≥99.5% (titration)
Packaging
25KG
Price
$7580
Updated
2024/03/01
Sigma-Aldrich
Product number
69947
Product name
MOPS
Purity
BioUltra, for molecular biology, ≥99.5% (T)
Packaging
25g
Price
$133
Updated
2024/03/01
Sigma-Aldrich
Product number
69947
Product name
MOPS
Purity
BioUltra, for molecular biology, ≥99.5% (T)
Packaging
100g
Price
$414
Updated
2024/03/01
More
Less

MOPS Chemical Properties,Usage,Production

Description

MOPS (3-morpholinopropanesulfonic acid) is a buffer introduced by Good et al. in the 1960s. It is a structural analog to MES. Its chemical structure contains a morpholine ring. HEPES is a similar pH buffering compound that contains a piperazine ring. With a pKa of 7.20, MOPS is an excellent buffer for many biological systems at near-neutral pH.It is used as a synthetic buffering agent below pH 7.5.

application

MOPS is frequently used as a buffering agent in biology and biochemistry. It has been tested and recommended for polyacrylamide gel electrophoresis. Usage above 20 mM in mammalian cell culture work is not recommended. MOPS buffer solutions become discolored (yellow) over time, but reportedly slight discoloration does not significantly affect the buffering characteristics.

Reference

P. H. Quail, D. Marme, E. Schäfer, Particle-bound phytochrome from maize and pumpkin, Nature New Biology, 1973, vol. 245, pp. 189-191

Chemical Properties

White/clear crystalline powder

Uses

MOPS acts as a multi-purpose buffering agent used in various biological research.

Uses

Due to its inert nature, 3-morpholinopropanesulfonic acid (MOPS) is widely used as a buffer in many biochemical studies. MOPS has been used as a cell culture additive component in lentiviral particle production,  a buffering agent in microbial growth medium and nuclei extraction buffer, a component of Roswell Park Memorial Institute (RPMI) medium for diluting fungal inoculum, and a buffer in capillary-zone electrophoresis to test performance. It is also used for the dilution of proteins from algal samples.

Definition

ChEBI: 3-(N-morpholino)propanesulfonic acid is a Good's buffer substance, pKa = 7.2 at 20 ℃. It is a member of morpholines, a MOPS and an organosulfonic acid. It is a conjugate acid of a 3-(N-morpholino)propanesulfonate. It is a tautomer of a 3-(N-morpholiniumyl)propanesulfonate.

General Description

3-(N-Morpholino)propane sulfonic acid (MOPS) is an N-substituted amino sulfonic acid with a morpholinic ring. MOPS is capable of buffering within a pH range of 6.5-7.9. MOPS is widely used in biological and biochemical studies due to its inert properties. It does not interact with any metal ions in solutions and has significant metal-buffer stability especially with copper (Cu), nickel (Ni), manganese (Mn), zinc (Zn), cobalt (Co) ions. MOPS buffer maintains the pH of the mammalian cell culture medium. MOPS functions to maintain pH in denaturing gel electrophoresis of RNA. MOPS can modify lipid interactions and influence the thickness and barrier properties of membranes. MOPS interacts with bovine serum albumin and stabilizes the protein. Hydrogen peroxide oxidizes MOPS slowly to N-oxide form.

Flammability and Explosibility

Not classified

Synthesis

Morpholine and 1,3-Propanesultone are added to absolute ethanol for reaction. The crude product synthesized is purified to obtain 3-Morpholinopropanesulfonic acid.

MOPS Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

MOPS Suppliers

Americas 1 Belgium 2 Canada 3 China 487 China Hong Kong 1 Czech Republic 1 Europe 5 France 4 Germany 14 India 32 Japan 6 Poland 1 Slovakia 1 South Korea 2 Switzerland 4 The Netherlands 2 Ukraine 1 United Kingdom 22 United States 83 USA 1 Global 673
WuHan Difu Biotechnology Co.Ltd
Tel
+86-17607151186; 18008681304
Email
898948847@qq.com
Country
China
ProdList
100
Advantage
58
Hubei New Desheng Materials Technology Co., Ltd.
Tel
0711-3702650 18971041571
Fax
0711-3704589
Email
vickyzhao@whdschem.com
Country
China
ProdList
57
Advantage
58
Nanjing Search Biotech Co., Ltd
Tel
+86-025-81682922 +86-13515111588
Fax
025-85860962
Email
sales@searchbio.com.cn
Country
China
ProdList
135
Advantage
68
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4552
Advantage
62
Hunan Waybel Advanced Materials Co.,Ltd
Tel
0745-2866851 17307457092
Email
ivy@hnhbsj.com
Country
China
ProdList
456
Advantage
60
Hubei ZhengXingyuan Chemical Co., Ltd.
Tel
027-87879183,027-87633098 15207106154
Fax
027-87877281
Email
2905723734@qq.com
Country
China
ProdList
284
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 13451648594
Fax
0512-87182056
Email
sales@yacoo.com.cn
Country
China
ProdList
4578
Advantage
58
Hunan Wokai Biotechnology Co., Ltd.
Tel
0744-2221508 13126795102
Fax
0744-6652010
Email
jack@oka-vip.com
Country
China
ProdList
317
Advantage
58
Hubei deante Chemical Technology Co., Ltd
Tel
15927262683
Email
3244356795@qq.com
Country
China
ProdList
727
Advantage
58
Hunan Hengfei bio-pharmaceutical Co. , Ltd.
Tel
0746-6222194 13874779848
Fax
0746-6222194
Email
57182844@qq.com
Country
China
ProdList
86
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Nanjing MeiBo Biological Technology Co., Ltd.
Tel
025-58619198
Fax
025-58619197
Email
sales@mbbio.com
Country
China
ProdList
319
Advantage
60
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Tangshan Moneide Trading Co., Ltd.
Tel
0315-8309571 15633399667
Fax
+86-315-7726572
Email
sales@moneidechem.com
Country
China
ProdList
704
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1931
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
972
Advantage
62
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3203
Advantage
55
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2871
Advantage
58
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Suzhou BEC Biological Technology Co., Ltd
Tel
+86-512-68095917 13862064516
Fax
+86-512-68417933
Email
sales@bek.com.cn
Country
China
ProdList
146
Advantage
59
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
More
Less

View Lastest Price from MOPS manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
MOPS 1132-61-2
Price
US $100.00-75.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-20
WUHAN FORTUNA CHEMICAL CO., LTD
Product
3-Morpholinopropanesulfonic acid 1132-61-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
3500kg/month
Release date
2021-09-09
Apeloa production Co.,Limited
Product
MOPS 1132-61-2
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000
Release date
2024-06-05

1132-61-2, MOPSRelated Search:

1,3-Propane sultone Dimethomorph Citric acid Folic acid p-Toluenesulfonic acid Morpholine Moroxydine hydrochloride Moroxydine Taurine Ethyl 2-(Chlorosulfonyl)acetate 1-DODECANESULFONIC ACID SODIUM SALT Tridemorph Ascoric Acid MORPHINE 3-MORPHOLINOPROPANESULFONIC ACID SODIUM SALT 3-MORPHOLINOPROPANESULFONIC ACID HEMISODIUM SALT,3-N-MORPHOLINOPROPANESULFONIC ACID HEMISODIUM SALT MOPSO sodium salt MOPS BUFFER

  • MOPS
  • MOPS, CONCENTRATE SOLUTION
  • MORPHOLINOPROPANE SULFONIC ACID
  • TIMTEC-BB SBB009133
  • 4-MORPHOLINEPROPANESULFONIC ACID
  • 4-(MORPHOLINOPROPANE SULFONIC ACID)
  • 3-MORPHOLINOPROPANESULFONIC ACID
  • 3-MORPHOLINOPROPANESULPHONIC ACID
  • 3-(N-MORPHOLINO)PROPANESULFONIC ACID
  • 3-(N-MORPHOLINO)PROPANESULPHONIC ACID
  • LABOTEST-BB LT00455082
  • LABOTEST-BB LT01595956
  • MOPS,BIOLOGICALBUFFER
  • 4-Morpholinopropansulfonsure
  • 4-MORPHOLINEPROPANESULFONIC ACID MOPS
  • MOPS ULTRAPURE
  • MOPS (3-MORPHOLINOPROPANESULFONIC ACID)
  • MOPS (3-MORPHOLINOPROPANESULFONIC ACID), HIGH PURITY
  • 3-MORPHOLINOPROPANESULPHONIC ACID extrapure
  • 3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid
  • WAS 15
  • 3-Morpholinopropanesulfonic acid ,99.5%
  • MOPS, 99%, FOR BIOCHEMISTRY
  • MOPS, 99.5%, DNASE, RNASE, PROT. FREE, FOR PEPTIDE SEQUENCING, FOR MOLECULAR BIOLOGY
  • MOPS, Dnase, Rnase, Prot. free, for peptide sequencing, for molecular biology
  • 3-(4-Morpholinyl)-1-propanesulfonic acid
  • 3-Morpholino-1-propanesulfonic acid
  • 3-Morpholinopropane-1-sulfonic acid
  • 4-Morpholinepropane-1-sulfonic acid
  • MOPS,99.5%,for molecular biology,Dnase, Rnase, Prot. free, for peptide sequencing
  • 3-(N-MORPHOLINO) PROPANESULPHONIC ACID, ULTRAPURE >99.5
  • 3-(N-Morpholino)propanesulphonic acid, low sodium >99.5%
  • MOPS low sodium
  • 3-Morpholinopropanesulfonic Acid [Good's buffer component for biological research]
  • Morpholinepropanesulfonic acid, 4-
  • MOPS1132-61-2
  • MOPS,3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid
  • 3-Morpholinopropanes
  • 3-(Morpholin-4-yl)propanesulphonic acid, ultrapure >99.5%
  • 3-N-Morpholinopropanesulfonic acidMolecular biology grade, ≥ 99.5% (Titration)
  • MOPS, Free Acid, Molecular Biology Grade
  • MOPS, Free Acid, ULTROL
  • MOPS, Cell culture tested
  • MOPS, DNAse, RNAse and Protease Free
  • MOPS, BIOPERFORMANCE CERTIFIED, CELL
  • MOPS, Free Acid, ULTROL Grade - CAS 1132-61-2 - Calbiochem
  • OmniPur MOPS - CAS 1132-61-2 - Calbiochem
  • 3-(N-MORPHOLINO)PROPANESULFONIC ACID3-(N-MORPHOLINO)PROPANESULFONIC ACID3-(N-MORPHOLINO)PROPANESULFONIC ACID3-(N-MORPHOLINO)PROPANESULFONIC ACID
  • MOPS, ≥99.5% (T)
  • MOPS, ≥99.0%(T)
  • 3-Morpholinopropanesulfonic acid 1132-61-2 4-Morpholinepropanesulfonic acid
  • 1132-61-2 4-Morpholinepropanesulfonic acid MOPS
  • MOPS FREE ACID, BIOTECHNOLOGY PERFORMANC E CERTIFIED
  • 3-Morpholinopropanesulfonic ac
  • 3-N-morpholinopropansulfonic acid
  • MOPS 3-(N-Morpholino)propanesulfonic acid
  • MOPS, 10X Liquid Concentrate,Molecular Biology Grade
  • MOPS, Free Acid, MB Grade (1.01545)