ChemicalBook > CAS DataBase List > Diethyl ketomalonate

Diethyl ketomalonate

Product Name
Diethyl ketomalonate
CAS No.
609-09-6
Chemical Name
Diethyl ketomalonate
Synonyms
Diethyl 2-oxomalonate;DIETHYL MESOXALATE;diethyl 2-oxopropanedioate;1,3-diethyl 2-oxopropanedioate;ketomaL;Keto Malonate;Ethyl mesoxalate;ETHYL OXOMALONATE;DIETHYL MESOXYLATE;Diethyl ketomalote
CBNumber
CB0224840
Molecular Formula
C7H10O5
Formula Weight
174.15
MOL File
609-09-6.mol
More
Less

Diethyl ketomalonate Property

Melting point:
-70°C
Boiling point:
208-210 °C (lit.)
Density 
1.142 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.415
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Methanol
form 
liquid
color 
green-yellow
Specific Gravity
1.142
Water Solubility 
Fully miscible with water.
Sensitive 
Moisture Sensitive
Merck 
14,5913
BRN 
971873
InChIKey
DBKKFIIYQGGHJO-UHFFFAOYSA-N
CAS DataBase Reference
609-09-6(CAS DataBase Reference)
NIST Chemistry Reference
Propanedioic acid, oxo-, diethyl ester(609-09-6)
EPA Substance Registry System
Propanedioic acid, oxo-, diethyl ester (609-09-6)
More
Less

Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
F 
21
Hazard Note 
Irritant
TSCA 
T
HazardClass 
IRRITANT, MOISTURE SENSITIVE
HS Code 
29183000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D97401
Product name
Diethyl ketomalonate
Purity
95%
Packaging
5g
Price
$56.6
Updated
2024/03/01
Sigma-Aldrich
Product number
D97401
Product name
Diethyl ketomalonate
Purity
95%
Packaging
25g
Price
$185
Updated
2024/03/01
TCI Chemical
Product number
M0866
Product name
Diethyl Mesoxalate
Purity
>94.0%(GC)
Packaging
5g
Price
$48
Updated
2024/03/01
TCI Chemical
Product number
M0866
Product name
Diethyl Mesoxalate
Purity
>94.0%(GC)
Packaging
25g
Price
$192
Updated
2024/03/01
Alfa Aesar
Product number
A12771
Product name
Diethyl ketomalonate, 95%
Packaging
5g
Price
$39.65
Updated
2024/03/01
More
Less

Diethyl ketomalonate Chemical Properties,Usage,Production

Chemical Properties

Clear yellow liquid

Uses

Diethyl ketomalonate, reagent employed in Wittig and Aza-Wittig reactions for synthesis of triazoles, and 2-azadienes, respectively.

Application

Diethyl ketomalonate can be used in electron-deficient heterodienophile; Diels-Alder reaction; heterodipolarophile; [3 + 2] cycloaddition; 1,3-diyl trapping agent; 1,4-dipolar cycloaddition; [2 + 2] cycloaddition; enophile; ene reaction; electrophilic addition; Wittig reactions; condensation with amines; Pictet-Spengler reactions.

Preparation

Diethyl ketomalonate can be prepared by bromination of Diethyl Malonate to the dibromomalonic ester, exchange of one bromine atom for acetate and α-elimination of acetyl bromide. Alternatively, diethyl malonate is condensed with benzaldehyde to afford the Knoevenagel product which is cleaved by ozonolysis.

Synthesis Reference(s)

Synthetic Communications, 24, p. 695, 1994 DOI: 10.1080/00397919408012648
The Journal of Organic Chemistry, 46, p. 2598, 1981 DOI: 10.1021/jo00325a039

storage

Diethyl ketomalonate is stable for at least 6 months if stored in the refrigerator.

Diethyl ketomalonate Preparation Products And Raw materials

Raw materials

Diethyl ester Malonic acid

Preparation Products

More
Less

Diethyl ketomalonate Suppliers

Americas 1 Belgium 2 China 241 Europe 2 Germany 6 India 25 Japan 4 Slovakia 1 Switzerland 3 United Kingdom 21 United States 37 Global 343
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
18478
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Aozeal Certified Standards (AOCS), Inc.
Tel
--
Fax
--
Email
info@aozeal.com
Country
United States
ProdList
504
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
Fine Chem Trading LTD
Tel
--
Fax
--
Email
chemfinder@chemfinder.co.uk
Country
United States
ProdList
1609
Advantage
64
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
TCI America, Inc. (part of Tokyo Chemical Industry)
Tel
--
Fax
--
Email
Angelina.Crew@tcichemicals.com
Country
United States
ProdList
2053
Advantage
58
Apex Scientific Inc.
Tel
--
Fax
--
Email
apex_sci@att.net
Country
United States
ProdList
188
Advantage
0
Rintech, Inc.
Tel
--
Fax
--
Email
info@rintechinc.com
Country
United States
ProdList
3416
Advantage
60
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Santa Cruz Biotechnology, Inc.
Tel
--
Fax
--
Email
scbt@scbt.com
Country
United States
ProdList
3597
Advantage
60
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Ryan Scientific, Inc.
Tel
--
Fax
--
Email
ryan.reichlyn@ryansci.com
Country
United States
ProdList
6439
Advantage
60
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Aceto Corporation
Tel
--
Fax
--
Email
contact@aceto.com
Country
United States
ProdList
2619
Advantage
75
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
City Chemical LLC
Tel
--
Fax
--
Email
sales@citychemical.com
Country
United States
ProdList
6708
Advantage
72
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Eastern Chemical Corp.
Tel
--
Fax
--
Email
eastern@u-g.com
Country
United States
ProdList
2786
Advantage
34
City Chemicals Corporation
Tel
--
Fax
--
Country
United States
ProdList
6460
Advantage
72
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
More
Less

View Lastest Price from Diethyl ketomalonate manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
Diethyl ketomalonate 609-09-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-25
Hebei Weibang Biotechnology Co., Ltd
Product
Diethyl ketomalonate 609-09-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-13
Honest Joy Holdings Limited
Product
Diethyl ketomalonate 609-09-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98.7%
Supply Ability
100 tons
Release date
2022-02-18

609-09-6, Diethyl ketomalonateRelated Search:

Diethyl dipropylmalonate Diethyl isopropylmalonate Diethyl chloromalonate DIETHYL DIMETHYLMALONATE Diethyl malonate Diethyl fluoromalonate Dimethyl malonate DIETHYL BROMOMALONATE Diethyl 2-ethyl-2-phenylmalonate Diethyl ethylmalonate Diethyl butylmalonate Malonic acid Diethyl methylmalonate 2-AMINODIETHYLMALONATE Diethyl bis(hydroxymethyl)malonate Diethyl phenylmalonate DIETHYL DIETHYLMALONATE Diethyl allylmalonate

  • 2-Oxopropanedioic acid diethyl
  • 2-Oxopropanedioic acid diethyl ester
  • Ketomalonic acid diethyl
  • Oxomalonic acid diethyl
  • Diethyl KETOMALONATE ester
  • Diethyl ketomalonate ,98%
  • Diethyl 2-oxomalonate 97%
  • Diethyl ketomalonate, (Diethyl mesoxalate
  • Diethyl mesoxalate~Diethyl oxomalonate~Oxopropanedioic acid diethyl ester
  • 2-Oxomalonic acid diethyl ester
  • DiethylKetomaloante
  • Diethylmesoxalate=Diethyloxomalonate
  • Diethylketomalonate,95%
  • Diethyl ketomalonate 97%
  • Diethyl 2-oxopropane-1,3-dioate, Diethyl ketomalonate
  • Diethyl ketoMalonate, 95% 25GR
  • Diethyl ketoMalonate, 95% 5GR
  • Propanedioic acid,2-oxo-, 1,3-diethyl ester
  • Diethyl Ketomalonate Mesoxalic Acid Diethyl Ester
  • Di ethyl keeto Malonate
  • Diethyl 2-oxopropane-1,3-dioate, Diethyl ketomalonate, Diethyl mesoxalate
  • diethyl 2-oxopropanedioate
  • Propanedioic acid, oxo-, diethyl ester
  • Diethyl ketomalonate, Ketomalonic acid diethyl ester
  • Diethyl mesoxalate, Ketomalonic acid diethyl ester
  • Sodium Valproate Impurity 16
  • 1,3-diethyl 2-oxopropanedioate
  • Keto Malonate
  • Diethyl ketoMalonate SynonyMs Diethyl Mesoxalate
  • MESOXALIC ACID DIETHYL ESTER
  • DIETHYL MESOXALATE
  • DIETHYL MESOXYLATE
  • DIETHYL KETOMALONATE
  • DIETHYL OXOMALONATE
  • ETHYL OXOMALONATE
  • KETOMALONIC ACID DIETHYL ESTER
  • Diethyl 2-oxomalonate
  • Ethyl mesoxalate
  • oxo-propanedioicacidiethylester
  • Diethyl ketomalonate≥ 98% (GC)
  • Diethyl ketomalote
  • ketomaL
  • DiethylMesoxalate&gt
  • Di Ethyl Ketomalonate (in GMs)
  • Diethyl divinyl ester
  • 609-09-6
  • COCO2C2H52
  • COCOOC2H52
  • Building Blocks
  • Carbonyl Compounds
  • C6 to C7
  • Esters
  • Organic Building Blocks
  • Pharmaceutical Intermediates