Diethyl fluoromalonate

Product Name: Diethyl fluoromalonate
CAS No.: 685-88-1
Chemical Name: Diethyl fluoromalonate
Synonyms: DIETHYL 2-FLUOROMALONATE;Propanedio;FLUOROMALONIC ACID DIETHYL ESTER;1,2-Difluoromalonate;Ethyl fluoromalonate;DIETHYL FLUOROMALONATE;Diethyl fluoromalonnate;DiethylfluoroMalonate96%;DiethylFluoromalonate>Diethylfluoromalonate,97%
CBNumber: CB6479224
Molecular Formula: C7H11FO4
Formula Weight: 178.16
MOL File: 685-88-1.mol

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Diethyl fluoromalonate Property

Boiling point:: 121-122 °C30 mm Hg(lit.)
Density: 1.129 g/mL at 25 °C(lit.)
refractive index: n20/D 1.407(lit.)
Flash point:: 144 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 10.40±0.46(Predicted)
form: Liquid
Specific Gravity: 1.129
color: Clear colorless to pale yellow
BRN: 1775686
InChI: InChI=1S/C7H11FO4/c1-3-11-6(9)5(8)7(10)12-4-2/h5H,3-4H2,1-2H3
InChIKey: GOWQBFVDZPZZFA-UHFFFAOYSA-N
SMILES: C(OCC)(=O)C(F)C(OCC)=O
CAS DataBase Reference: 685-88-1(CAS DataBase Reference)
NIST Chemistry Reference: Diethyl fluoromalonate(685-88-1)

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Safety

Hazard Codes: C,T
Risk Statements: 34
Safety Statements: 26-36/37/39-45-25-27
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
RTECS: OO1670000
F: 19
Hazard Note: Corrosive
HazardClass: 8
PackingGroup: III
HS Code: 29171900
Storage Class: 8A - Combustible corrosive hazardous materials
Hazard Classifications: Skin Corr. 1B

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 285587
Product name: Diethyl fluoromalonate
Purity: 97%
Packaging: 1ml
Price: $95.8
Updated: 2025/07/31

TCI Chemical

Product number: F0283
Product name: Diethyl Fluoromalonate
Purity: >95.0%(GC)
Packaging: 1g
Price: $33
Updated: 2025/07/31

TCI Chemical

Product number: F0283
Product name: Diethyl Fluoromalonate
Purity: >95.0%(GC)
Packaging: 5g
Price: $82
Updated: 2025/07/31

TCI Chemical

Product number: F0283
Product name: Diethyl Fluoromalonate
Purity: >95.0%(GC)
Packaging: 25g
Price: $401
Updated: 2025/07/31

TRC

Product number: D477258
Product name: Diethyl fluoromalonate
Packaging: 1g
Price: $50
Updated: 2021/12/16

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Diethyl fluoromalonate Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO PALE YELLOW LIQUID

Uses

The kinetic parameters of diethyl fluoromalonate in hemolysates were used to study carboxylesterase activities in complex systems.

General Description

The reaction of diethyl fluoromalonate with electron-poor and electron-rich, sterically hindered and unhindered aryl bromides and chlorides were studied.

Synthesis

In a 250m1 round bottom flask, 5g of sodium carbonate, 10g of cobalt octacarbonyl, 72ml (57g, 1. 25mol) of ethanol and 53ml (61g, 0. 5mol) of ethyl chloroacetate were added, and CO2 was passed through the gas at a flow rate of 50m1/min for 6h, and the reaction was completed. To the system was added 5 m1 of concentrated sulfuric acid, shaken for 15 min, and then distilled under reduced pressure to collect the 80C/4 mmHg fraction. Add 60ml of water to the distillate, adjust the pH to 0.3 with concentrated sulfuric acid, vibrate, separate the organic layer, and then carry out decompression distillation to collect 80C/ 4mmHg fraction, obtaining diethyl malonate 66~69ml (69.6g ~ 72.8g), the yield was about 87% ~ 91%.

16.0g(0.1mol) diethyl malonate and 47.0g(0.12mol) HTIB were added to an aluminum container, and heated by irradiation for 3min in a 700W microwave oven, cooled, and 19.0g of MgCl was added, and heated by irradiation for 2min, cooled, and extracted with 50ml of CH,Cl2 for two times, dried with anhydrous magnesium sulfate, and evaporated to remove the CH2Cl2 to obtain Diethyl chloromalonate. Diethyl chloromalonate 15.7g, yield 81%.

Diethyl fluoromalonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Diethyl fluoromalonate Suppliers

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View Lastest Price from Diethyl fluoromalonate manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Diethyl fluoromalonate 685-88-1
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-07-18

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Diethyl fluoromalonate 685-88-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-11-20

Henan Aochuang Chemical Co.,Ltd.

Product: Diethyl fluoromalonate 685-88-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-29

685-88-1, Diethyl fluoromalonateRelated Search:

2-AMINODIETHYLMALONATE Diisopropyl malonate Mefenpyr-diethyl Ethyl hydrogen malonate Diethyl methylmalonate Diethyl carbonate Ethyl bromodifluoroacetate Diethyl phthalate DIETHYL BROMOMALONATE Diethyl chloromalonate Diethyl malonate Diethyl ether Malonic acid DIETHYL 2-BROMO-2-FLUORO-MALONATE Diethyl 2,2-difluoromalonate 2-FLUORO-2-METHANESULFONYLOXYMETHYL-MALONIC ACID DIETHYL ESTER DIETHYL 2-FLUORO-2-METHYL-MALONATE Diethyl fluoromalonate

Diethyl 2-fluoropropane-1,3-dioate

1,2-Difluoromalonate

1,3-diethyl 2-fluoropropanedioate

diethyl 2-fluoropropanedioate

Propanedio

diethylfluoropropanedioate

Ethyl fluoromalonate

fluoro-malonicacidiethylester

fluoro-propanedioicacidiethylester

Malonic acid, fluoro-, diethyl ester

Monofluoromalonic acid diethyl ester

Propanedioic acid, fluoro-, diethyl ester

2-FLUORO-MALONIC ACID DIETHYL ESTER

DiethylfluoroMalonate96%

DIETHYL 2-FLUOROMALONATE

DIETHYL FLUOROMALONATE

FLUOROMALONIC ACID DIETHYL ESTER

Diethylfluoromalonate,97%

fluoropropanedioic acid diethyl ester

Diethyl 2-fluoromalonate 97%

Diethyl2-fluoromalonate97%

Diethyl fluoromalonnate

DiethylFluoromalonate&gt

Propanedioic acid, 2-fluoro-, 1,3-diethyl ester

Diethyl fluoro-malonic acid

TIANFU-CHEM - Diethyl fluoromalonate

2-fluoro-Propanedioic acid 1,3-diethyl ester

2-Fluoro-malonic acid 1,3-diethyl ester

685-88-1

658-88-1

985-88-1

C7H11FO4

FCHCOOC2H52

FCHCO2CH2CH32

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