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Ethyl hydrogen malonate

Product Name
Ethyl hydrogen malonate
CAS No.
1071-46-1
Chemical Name
Ethyl hydrogen malonate
Synonyms
MONOETHYL MALONATE;Monoethyl malonic acid;3-ethoxy-3-oxopropanoate;3-ethoxy-3-oxapropanoic acid;3-ethoxy-3-oxo-propanoic acid;en maL;BROP-001;hydrogen maL;Malonic acid 1-ethyl;Ethyl hydrogen malon
CBNumber
CB6477583
Molecular Formula
C5H8O4
Formula Weight
132.11
MOL File
1071-46-1.mol
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Ethyl hydrogen malonate Property

Melting point:
-13°C(lit.)
Boiling point:
106.5 °C/3 mmHg (lit.)
Density 
1.119 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.435(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Sparingly)
pka
pK1:3.55 (25°C)
form 
Liquid
color 
Pale yellow
Water Solubility 
Miscible with water, chloroform and other solvents.
BRN 
1758845
InChIKey
HGINADPHJQTSKN-UHFFFAOYSA-N
CAS DataBase Reference
1071-46-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29171900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
445088
Product name
mono-Ethyl malonate
Packaging
5g
Price
$58.1
Updated
2024/03/01
TCI Chemical
Product number
M2700
Product name
Monoethyl Malonate
Purity
>98.0%(T)
Packaging
5g
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
M2700
Product name
Monoethyl Malonate
Purity
>98.0%(T)
Packaging
25g
Price
$105
Updated
2024/03/01
Alfa Aesar
Product number
044692
Product name
Ethyl hydrogen malonate, 90+%
Packaging
5g
Price
$31.65
Updated
2024/03/01
Alfa Aesar
Product number
044692
Product name
Ethyl hydrogen malonate, 90+%
Packaging
25g
Price
$102.65
Updated
2024/03/01
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Ethyl hydrogen malonate Chemical Properties,Usage,Production

Chemical Properties

Yellow liquid

Uses

Ethyl hydrogen malonate is used as a reactant for the preparation of tetramic acids through Dieckmann ring closure and organocatalytic decarboxylative Doebner-Knoevenagel reactions. It is involved in the acylation reactions and Knoevenagel condensation with aldehydes. It is also used in the preparation of gamma-lactones from olefins by intermolecular carbolactonization in presence of Mn(III) acetate as a catalyst.

Uses

Ethyl Hydrogen Malonate has been shown to impair brain mitochondrial succinate and malate transport. It is also found in the extract of Hericum erinaceus mushroom which shows antitumor effects in tumo r-bearing mice.

Definition

ChEBI: Monoethyl malonic acid is a dicarboxylic acid.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 4, p. 417, 1963
Tetrahedron Letters, 26, p. 1411, 1985 DOI: 10.1016/S0040-4039(00)99058-0

Ethyl hydrogen malonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl hydrogen malonate Suppliers

Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Tianjin Ji Ping Jia Chemical Co., Ltd.
Tel
18622448868
Fax
022-58620773
Email
jpjchem@163.com
Country
China
ProdList
476
Advantage
62
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
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View Lastest Price from Ethyl hydrogen malonate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Ethyl hydrogen malonate 1071-46-1
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-07-07
Hebei Mingeng Biotechnology Co., Ltd
Product
Monoethyl malonic acid 1071-46-1
Price
US $300.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
500kg/month
Release date
2022-05-05
Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl hydrogen malonate 1071-46-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-29

1071-46-1, Ethyl hydrogen malonateRelated Search:


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  • HO2CCH2CO2CH2CH3
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