ChemicalBook > CAS DataBase List > Ethyl hydrogen malonate

Ethyl hydrogen malonate

Product Name
Ethyl hydrogen malonate
CAS No.
1071-46-1
Chemical Name
Ethyl hydrogen malonate
Synonyms
MONOETHYL MALONATE;Monoethyl malonic acid;3-ethoxy-3-oxopropanoate;3-ethoxy-3-oxapropanoic acid;3-ethoxy-3-oxo-propanoic acid;en maL;BROP-001;hydrogen maL;Malonic acid 1-ethyl;Ethyl hydrogen malon
CBNumber
CB6477583
Molecular Formula
C5H8O4
Formula Weight
132.11
MOL File
1071-46-1.mol
More
Less

Ethyl hydrogen malonate Property

Melting point:
-13°C(lit.)
Boiling point:
106.5 °C/3 mmHg (lit.)
Density 
1.119 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.435(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Sparingly)
pka
pK1:3.55 (25°C)
form 
Liquid
color 
Pale yellow
Water Solubility 
Miscible with water, chloroform and other solvents.
BRN 
1758845
InChIKey
HGINADPHJQTSKN-UHFFFAOYSA-N
CAS DataBase Reference
1071-46-1(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29171900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
445088
Product name
mono-Ethyl malonate
Packaging
5g
Price
$58.1
Updated
2024/03/01
TCI Chemical
Product number
M2700
Product name
Monoethyl Malonate
Purity
>98.0%(T)
Packaging
5g
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
M2700
Product name
Monoethyl Malonate
Purity
>98.0%(T)
Packaging
25g
Price
$105
Updated
2024/03/01
Alfa Aesar
Product number
044692
Product name
Ethyl hydrogen malonate, 90+%
Packaging
5g
Price
$31.65
Updated
2024/03/01
Alfa Aesar
Product number
044692
Product name
Ethyl hydrogen malonate, 90+%
Packaging
25g
Price
$102.65
Updated
2024/03/01
More
Less

Ethyl hydrogen malonate Chemical Properties,Usage,Production

Chemical Properties

Yellow liquid

Uses

Ethyl hydrogen malonate is used as a reactant for the preparation of tetramic acids through Dieckmann ring closure and organocatalytic decarboxylative Doebner-Knoevenagel reactions. It is involved in the acylation reactions and Knoevenagel condensation with aldehydes. It is also used in the preparation of gamma-lactones from olefins by intermolecular carbolactonization in presence of Mn(III) acetate as a catalyst.

Uses

Ethyl Hydrogen Malonate has been shown to impair brain mitochondrial succinate and malate transport. It is also found in the extract of Hericum erinaceus mushroom which shows antitumor effects in tumo r-bearing mice.

Definition

ChEBI: Monoethyl malonic acid is a dicarboxylic acid.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 4, p. 417, 1963
Tetrahedron Letters, 26, p. 1411, 1985 DOI: 10.1016/S0040-4039(00)99058-0

Ethyl hydrogen malonate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Ethyl hydrogen malonate Suppliers

Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Tianjin Ji Ping Jia Chemical Co., Ltd.
Tel
18622448868
Fax
022-58620773
Email
jpjchem@163.com
Country
China
ProdList
476
Advantage
62
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1931
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ:3470079902
Email
675141927@qq.com
Country
China
ProdList
3203
Advantage
55
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
3999
Advantage
55
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5047
Advantage
50
Suzhou Sibian Chemical Technology Co.,Ltd.
Tel
0512-65617459 18915409046
Fax
0512-65617459
Email
sales@sibian-chem.com
Country
China
ProdList
1922
Advantage
55
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8878
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Wuxi Zhangkun Biochemical Technology Co., Ltd.
Tel
+86 0510-85629785
Fax
+86 0510-85625359
Country
China
ProdList
2327
Advantage
58
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1972
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3991
Advantage
60
ChemiK Co., Ltd.
Tel
+86 574 8729 6330
Fax
+86 574 8729 7461
Email
info@chemik.com
Country
China
ProdList
3616
Advantage
61
Mei Lan Industrial (Shanghai) Co., Ltd.
Tel
021-58958189
Fax
021-58957967
Email
wouchina@126.com
Country
China
ProdList
2666
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Tianjin Olefin Pharmaceutical Co., Ltd.
Tel
18202662021
Fax
022-25541300
Email
2211422945@qq.com
Country
China
ProdList
317
Advantage
56
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Changzhou Qinuo Chemical Co., Ltd.Co., Ltd.
Tel
0519-0519-83812535
Email
sales@qinuochem.com
Country
China
ProdList
287
Advantage
60
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4943
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10276
Advantage
55
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ:3154870176
Email
mafarm@126.com
Country
China
ProdList
4307
Advantage
58
Shanghai Xingui Biotechnology Co., Ltd.
Tel
17501653715
Email
xingui2022@126.com
Country
China
ProdList
10021
Advantage
58
More
Less

View Lastest Price from Ethyl hydrogen malonate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Ethyl hydrogen malonate 1071-46-1
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-07-07
Hebei Mingeng Biotechnology Co., Ltd
Product
Monoethyl malonic acid 1071-46-1
Price
US $300.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
500kg/month
Release date
2022-05-05
Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl hydrogen malonate 1071-46-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-29

1071-46-1, Ethyl hydrogen malonateRelated Search:


  • ETHYL HYDROGEN MALONATE
  • MONOETHYL MALONATE
  • 3-ethoxy-3-oxapropanoic acid
  • Monoethyl malonic acid
  • 3-ethoxy-3-oxo-propanoic acid
  • Ethyl hydrogen malonate, 90+%
  • Ethoxycarbonylacetic acid
  • Malonic acid 1-ethyl
  • Malonic acid 1-ethyl ester
  • Malonic acid hydrogen 1-ethyl ester
  • malonic acid half ethyl ester
  • 3-ethoxy-3-keto-propionic acid
  • Ethyl hydrogen malon
  • Monoethyl hydrogen malonate
  • Propanedioic acid, 1-ethyl ester
  • BROP-001
  • Ethyl hydrogen malonate, technical, 90%
  • 3-ethoxy-3-oxopropanoate
  • en maL
  • Cabozantinib impurity 59
  • Monoethyl Malonate &gt
  • hydrogen maL
  • Valproic Acid Impurity 34
  • Ethyl Hydrogen Malanoate(MEM)
  • ETHYL HYDROGENMALONATE 3-ethoxy-3-oxo-propanoic acid mono-Ethyl malonate
  • 1071-46-1
  • HO2CCH2CO2CH2CH3
  • HO2CCH2CO2C2H5
  • C5H8O4
  • Organic Building Blocks
  • Esters
  • CARBOXYLIC ACID
  • Building Blocks
  • C2 to C5
  • Carbonyl Compounds
  • Thiophenes ,Thiazolines/Thiazolidines
  • Small molecule
  • API intermediates
  • C2 to C5
  • Carbonyl Compounds
  • Esters
  • bc0001