2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE

Product Name: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE
CAS No.: 6564-72-3
Chemical Name: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE
Synonyms: Voglibose int;benzylglucopyranose;Tetrabenzyl glucose;Voglibose Impurity 1;Voglibose TBG IMpurity;Voglibose TBG impurities;Voglibose alpha-TBG Impurity;2,3,4,6-tetra-o-benzyl-d-glucose;6-Tetra-O-benzyl-D-glucopyranose;2,3,4,6-Tetra-o-benzyl-D-glucopyransoe
CBNumber: CB0234449
Molecular Formula: C34H36O6
Formula Weight: 540.66
MOL File: 6564-72-3.mol

More

Less

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Property

Melting point:: 151-156 °C
Boiling point:: 672.4±55.0 °C(Predicted)
Density: 1.22
storage temp.: Sealed in dry,Store in freezer, under -20°C
pka: 11.87±0.70(Predicted)
Water Solubility: Soluble in CHCl3. Insoluble in water.
LogP: 5.9 at 20℃ and pH6.5
CAS DataBase Reference: 6564-72-3(CAS DataBase Reference)

More

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Alfa Aesar

Product number: H31595
Product name: 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose, 98%
Packaging: 1g
Price: $55.65
Updated: 2024/03/01

Alfa Aesar

Product number: H31595
Product name: 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose, 98%
Packaging: 5g
Price: $180.65
Updated: 2024/03/01

TRC

Product number: P992030
Product name: 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranose
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: P992030
Product name: 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranose
Packaging: 500mg
Price: $90
Updated: 2021/12/16

Usbiological

Product number: 294905
Product name: 2,3,4,6-Tetra-O-benzoyl-D-glucopyranose
Packaging: 100mg
Price: $375
Updated: 2021/12/16

More

Less

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Chemical Properties,Usage,Production

Description

2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a selectively protected intermediate, where the anomeric 1-O-hydroxyl group is free. This hemiacetal has been used successfully as an intermediate for glucosylation couplings, where it was converted into 2,3,4,6-tetra-O-benzyl-D-glucopyranose trichloroacetimidate using trichloroacetonitrile in the presence of a base such as potassium carbonate and DBU.
Importantly, this imidate donor with no neighbouring participating groups is commonly used for the selective formation of glucosides. 2,3,4,6-tetra-O-benzyl-D-glucopyranose can also be oxidized to the lactone, or reduced to give the open chain form.
Additionally, 2,3,4,6-tetra-O-benzyl-D-glucopyranose can be used for the preparation of glucono-1,5-lactone hydrazine, which was used, in-turn, to form a glucosylidene-spirocyclopropane.

Uses

It is the intermediate of Voglibose/Dapagliflozin. An important D-glucopyranose derivative for glucosylations and other reactions 1,2; Preparation of the α-glucopyranosyl chloride, synthesis of 1-C-α-D-glucopyranose derivatives.

Synthesis

Octa-O-Dissolves benzyl sucrose or octa-O-allyl sucrose in an organic solvent with the addition of hydrochloric acid without prior chromatographic purification, allows it to react for 20-60 minutes at temperatures of 50-60 °C. and then cleans the end product formed by crystallization. (ethanol, isopropanol, acetone, benzene, toluene or mixtures thereof can be used as solvents).

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Suppliers

Canada 2 China 229 Czech 1 France 1 Germany 7 India 7 Japan 1 Poland 1 Slovakia 1 Switzerland 4 The Netherlands 1 United Kingdom 8 United States 27 Global 290

Zhejiang Synose Tech Co., Ltd.

Tel: 0579-89172082 18720986928
Fax: 0579-89172082
Email: 191094223@qq.com
Country: China
ProdList: 63
Advantage: 58

Shanghai Jinli Pharmaceutical Co.,Ltd.

Tel: +86-021-57256005 +86-15921811235
Email: chang@shjlchem.com
Country: China
ProdList: 9
Advantage: 58

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3576
Advantage: 66

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2341
Advantage: 56

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10194
Advantage: 62

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

More

Less

View Lastest Price from 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2,3,4,6-tetra-O-benzyl-D-glucopyranose 6564-72-3
Price: US $0.00/g
Min. Order: 10g
Purity: 98.0%
Supply Ability: 500kg/month
Release date: 2021-07-14

Hebei Mojin Biotechnology Co., Ltd

Product: 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE 6564-72-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-08-24

Hebei Guanlang Biotechnology Co., Ltd.

Product: 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE 6564-72-3
Price: US $10.00/PCS
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2021-04-28

6564-72-3, 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSERelated Search:

(S)-Valiolamine Voglibose Valiolamine (2S,3S,4S,5S)-5-Hydroxy-2,3,4-tris(phenylMethoxy)-5-[(phenylMethoxy)Methyl]-cyclohexanone (R)-Valiolamine Voglibose ETHYL 2,3,4,6-TETRA-O-ACETYL-ALPHA-D-THIOGLUCOPYRANOSIDE Methyl-2,3,5-tri-O-benzoyl-alpha-D-arabinofuranoside 2,3,4,6-TETRA-O-ACETYL-ALPHA-D-MANNOPYRANOSYL AZIDE Methyl beta-D-ribofuranoside 2,3,4,6-TETRA-O-ACETYL-BETA-D-GLUCOPYRANOSYL ISOTHIOCYANATE 2-Deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl azide 3,4,6-Triacetate FMOC-SER(GALNAC(AC)3-ALPHA-D)-OH Penta-O-benzoyl-alpha-D-mannopyranose 2-Deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-α-D-glucopyranosyl azide 3,4,6-Triacetate FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH D-Galactose 2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl bromide 2,3,4,6-Tetra-O-acetyl-alpha-D-galactopyranosyl bromide 2,3,4,6-Tetra-O-benzyl-D-glucopyranose

2,3,4,6-Tetra-O-benzyl-alpha-D-glucose (for Voglibose)

Voglibose int

Voglibose Impurity 1

2,3,4,6-Tetra-O-benzyl-D-glycopyranose

2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSIDE

2,3,4,6-TETRA-O-BENZOYL-D-GLUCOPYRANOSE

2,3,4,6-Tetra-O-benzyl-alpha-D-glucose

benzylglucopyranose

6-Tetra-O-benzyl-D-glucopyranose

2,3,4,6-tetra-o-benzyl-d-glucose

2,3,4,6-Tetra-o-benzyl-D-glucopyransoe

2,3,4,6-Tetra-O-benzyl-a-D-glucopyranose

2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE ,GB

2,3,4,6-TETRA-O-ACETYL A-D-GLUCOPYRANOSIDE

2,3,4,6-Tetra-O-benzyl-α-D-glucopyranos

alpha-D-Glucopyranose, 2,3,4,6-tetrakis-O-(phenylMethyl)-

a-D-Glucopyranose,2,3,4,6-tetrakis-O-(phenylMethyl)-

Voglibose TBG IMpurity

(2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)Methyl)tetrahydro-2H-pyran-2-ol

2,3,4,6-Tetra-O-benzyl-alpha-D-glucose SynonyMs 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose

2,3,4,6-Tetra-O-benzyl-alpha-D-glucose 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose

Voglibose TBG impurities

Voglibose alpha-TBG Impurity

2,3,4,6-Tetra-O-benzyl-α-D-glucopyranose

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOSE 6564-72-3

2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE USP/EP/BP

2,3,4,6-TETRA-O-BENZYL-ALPHA GLUCOPYRANOSE（COM）

2,3,4,6-TETRA-O-BENZYL-D-GLUCChemicalbookOPYRANOSE

2,3,4,6-Tetra-O-benzyl-D-glucopyranose(TBG)

2,3,4,6-Tetrakis-O-(phenylmethyl)-α-D-glucopyranose

α-D-Glucopyranose, 2,3,4,6-tetrakis-O-(phenylmethyl)-

Tetrabenzyl glucose

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE

6564-72-3

Specialty Synthesis

Monosaccharides

Monosaccharide

O-Substituted Sugars

Sugars

Carbohydrate Synthesis

Carbohydrates

Biochemicals and Reagents

BioChemical

Pharmaceutical Intermediates

6564-72-3