ChemicalBook > CAS DataBase List > 4-(3-Chloropropyl)morpholine

4-(3-Chloropropyl)morpholine

Product Name
4-(3-Chloropropyl)morpholine
CAS No.
7357-67-7
Chemical Name
4-(3-Chloropropyl)morpholine
Synonyms
4-(3-ChL;NSC 38889;NSC 28831;)-morphoL;N-(3-Chloropropyl)M;IFLAB-BB F2108-0002;Gefitinib iMpurity A;Gefitinib IMpurity VI;Gefitinib Impurity 81;3-morpholinopropylchloride
CBNumber
CB0240217
Molecular Formula
C7H14ClNO
Formula Weight
163.65
MOL File
7357-67-7.mol
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4-(3-Chloropropyl)morpholine Property

Melting point:
NA
Boiling point:
115°C/25mmHg(lit.)
Density 
1.0409 g/cm3
RTECS 
QE0488000
refractive index 
1.4720-1.4760
Flash point:
91 °C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
pka
7.03±0.10(Predicted)
Specific Gravity
1.08
color 
Colourless to Yellow
InChI
InChI=1S/C7H14ClNO/c8-2-1-3-9-4-6-10-7-5-9/h1-7H2
InChIKey
PQECODMSWJOUAT-UHFFFAOYSA-N
SMILES
N1(CCCCl)CCOCC1
CAS DataBase Reference
7357-67-7(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C2602
Product name
4-(3-Chloropropyl)morpholine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
C2602
Product name
4-(3-Chloropropyl)morpholine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$92
Updated
2024/03/01
Alfa Aesar
Product number
H35222
Product name
4-(3-Chloropropyl)morpholine, 95%
Packaging
10g
Price
$57.65
Updated
2024/03/01
Alfa Aesar
Product number
H35222
Product name
4-(3-Chloropropyl)morpholine, 95%
Packaging
50g
Price
$185.65
Updated
2024/03/01
TRC
Product number
C379750
Product name
4-(3-Chloropropyl)morpholine
Packaging
1g
Price
$80
Updated
2021/12/16
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4-(3-Chloropropyl)morpholine Chemical Properties,Usage,Production

Description

4-(3-Chloropropyl)morpholine is a hydrochloride salt of the potent inhibitor 4-(3-chloropropyl)morpholine. It has an inhibitory effect on cancer, and is used in chromatographic science to separate amines from aliphatic hydrocarbons. 4-(3-Chloropropyl)morpholine inhibits epidermal growth factor (EGF) and has been shown to have a potent inhibitory effect on EGF receptor tyrosine kinase activity. It also inhibits the proliferation of cells by inhibiting DNA synthesis. This compound causes cell death through the inhibition of protein synthesis, which may be due to its ability to inhibit nucleophilic reactions that are involved in protein synthesis. 4-(3-Chloropropyl)morpholine can also fluoresce under UV light, which makes it useful for research purposes.

Chemical Properties

Pale Yellow Oil

Uses

Gefitinib intermediate.

Application

4-(3-Chloropropyl)morpholine is an organic synthetic reagent or pharmaceutical intermediate used in the synthesis of gefitinib. It has cancer-inhibiting properties and inhibits epidermal growth factor (EGF). It also inhibits cell proliferation by inhibiting DNA synthesis.

4-(3-Chloropropyl)morpholine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(3-Chloropropyl)morpholine Suppliers

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View Lastest Price from 4-(3-Chloropropyl)morpholine manufacturers

Nanjing Fred Technology Co., Ltd
Product
4-(3-Chloropropyl)morpholine 7357-67-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
ton
Release date
2023-11-14
Henan Fengda Chemical Co., Ltd
Product
4-(3-Chloropropyl)morpholine 7357-67-7
Price
US $8.00-0.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-14
LY Global chemicals co.,ltd .
Product
N-(3-Chloropropyl)morpholine 7357-67-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98.0%min
Supply Ability
100kg
Release date
2023-03-11

7357-67-7, 4-(3-Chloropropyl)morpholineRelated Search:

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  • 4-(3-CHLOROPROPYL)-MORPHOLINE HYDROCHLORIDE
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  • 3-(Morpholin-4-yl)propyl Chloride
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  • 4-(3-chloropropyl)morpholine(SALTDATA: FREE)
  • N-(3-Chloropropyl)M
  • 4-(3-Chloropropyl) Morpholine Gefitinib HCL Side Chain
  • Gefitinib IMpurity VI
  • IFLAB-BB F2108-0002
  • 4-(3-CHLORO-PROPYL)-MORPHOLINE
  • 4-(3-CHLOROPROPYL)MORPHOLINE HCL
  • 1-Chloro-3-(morpholin-4-yl)propane
  • Gefitinib iMpurity A
  • 4-(3-Chloropropyl)morpholine &gt
  • Gefitinib Impurity 81
  • )-morphoL
  • 4-(3-Chloropropyl)morpholineQ: What is 4-(3-Chloropropyl)morpholine Q: What is the CAS Number of 4-(3-Chloropropyl)morpholine Q: What is the storage condition of 4-(3-Chloropropyl)morpholine Q: What are the applications of 4-(3-Chloropropyl)morpholine
  • Gefitinib Intermediate VIII
  • N-(3-Chloropropyl)morpholin
  • 7357-67-7
  • ETHER
  • Gefitinib
  • Aromatic Morpholines
  • Benzomorpholines & Benzothiomorpholines
  • Methyl Halides
  • Morpholines & Thiomorpholines
  • API intermediates
  • Heterocycles
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Benzomorpholines & Benzothiomorpholines
  • Methyl Halides
  • Morpholines & Thiomorpholines