5-ETHYNYL-2'-DEOXYURIDINE

Product Name: 5-ETHYNYL-2'-DEOXYURIDINE
CAS No.: 61135-33-9
Chemical Name: 5-ETHYNYL-2'-DEOXYURIDINE
Synonyms: abs9124;EYdU;5-E-dU;Uridine,2;Aids072372;Aids-072372;5-Ethynyl-dU;-deoxyuridine;5-Ethynyl-durd;5-Ethynyl-2'-dU
CBNumber: CB0243359
Molecular Formula: C11H12N2O5
Formula Weight: 252.22
MOL File: 61135-33-9.mol

More

Less

5-ETHYNYL-2'-DEOXYURIDINE Property

Melting point:: 199°C(lit.)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO (up to 10 mg/ml).
pka: 8.29±0.10(Predicted)
form: powder
color: White or off-white
Appearance: light beige to light brown solid
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChI: InChI=1S/C11H12N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h1,4,7-9,14-15H,3,5H2,(H,12,16,17)/t7-,8+,9+/m0/s1
InChIKey: CDEURGJCGCHYFH-DJLDLDEBSA-N
SMILES: OC[C@H]1O[C@@H](N2C=C(C#C)C(=O)NC2=O)C[C@@H]1O
CAS DataBase Reference: 61135-33-9

More

Less

Safety

Hazard Codes: T
Risk Statements: 46-61
Safety Statements: 53-45-24/25
RTECS: YU7510000
HS Code: 29349990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H340May cause genetic defects

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P308+P313IF exposed or concerned: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 900584
Product name: 5-Ethynyl-2′-deoxyuridine
Purity: 95%
Packaging: 50mg
Price: $152
Updated: 2025/07/31

Sigma-Aldrich

Product number: 900584
Product name: 5-Ethynyl-2′-deoxyuridine
Purity: 95%
Packaging: 500mg
Price: $1007
Updated: 2025/07/31

TCI Chemical

Product number: E1057
Product name: 5-Ethynyl-2'-deoxyuridine
Purity: >98.0%(HPLC)(T)
Packaging: 50mg
Price: $85
Updated: 2025/07/31

TCI Chemical

Product number: E1057
Product name: 5-Ethynyl-2'-deoxyuridine
Purity: >98.0%(HPLC)(T)
Packaging: 200mg
Price: $245
Updated: 2025/07/31

Cayman Chemical

Product number: 20518
Product name: 5-Ethynyl-2'-deoxyuridine
Purity: ≥98%
Packaging: 50mg
Price: $44
Updated: 2024/03/01

More

Less

5-ETHYNYL-2'-DEOXYURIDINE Chemical Properties,Usage,Production

Description

5-Ethynyl-2′-deoxyuridine (61135-33-9) is a novel agent for fast and sensitive detection of DNA synthesis?in vivo.1 5-EdU is incorporated into proliferating cells followed by detection with a fluorescent azide using click ligation.1 In contrast to the use of BrdU, the new method does not require sample fixation or DNA denaturation. 5-Ethynyl-2′-deoxyuridine may be used for studying cell proliferation in the central nervous system and may be combined with BrdU staining in a novel protocol allowing for double labeling of DNA synthesis.2

Uses

5-Ethynyl-2’deoxyuridine is a extensively used nucleoside analog used as a probe for DNA synthesis. However, 5-Ethynyl-2’deoxyuridine is a toxic anti-metabolite, which potentially causes DNA instabi liy, necrosis and cell-cycle arrest, therefore it is often used for short-term DNA synthesis in tissue culture and living organisms where prolonged cell survival is not required.

Uses

5-Ethynyl-2′-deoxyuridine (EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferation. It has an alkyne handle that can ligate with azide-containing fluorescent probes through a highly efficient click chemistry reaction. EdU nucleoside can be incorporated into the DNA of cells either in culture or in animals without showing significant toxicity. The assay offers a simpler workflow for detecting cell proliferation than anti-BrdU assays.

For information on Baseclick kits containing all the reagents for the assays see: Baseclick kits

For a listing of the Baseclick kits see: Baseclick kits

storage

Store at -20°C

References

[1] ADRIAN SALIC Timothy J M. A chemical method for fast and sensitive detection of DNA synthesis in vivo.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2008, 105 7: 2415-2420. DOI:10.1073/pnas.0712168105
[2] CHENBO ZENG . Evaluation of 5-ethynyl-2′-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system[J]. Brain Research, 2010, 1319: Pages 21-32. DOI:10.1016/j.brainres.2009.12.092

5-ETHYNYL-2'-DEOXYURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-ETHYNYL-2'-DEOXYURIDINE Suppliers

Americas 1 Australia 2 Canada 1 China 213 Europe 1 France 1 Germany 2 India 5 Japan 1 United Kingdom 2 United States 13 Global 242

Wuhu Nuowei Chemical Technology Co., Ltd

Tel: 0553-0553-8233716-803-803 18055326116
Email: sales@nuowei-chem.com
Country: China
ProdList: 953
Advantage: 55

Fuyang Ziyi Biological Pharmaceutical Co., Ltd.

Tel: 19308655899; 19308655899
Fax: -
Email: 2677609105@qq.com
Country: China
ProdList: 500
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Hongene Biotech Corporation

Tel: 021-64757213
Fax: 86-21-64700613
Email: info@hongene.com
Country: China
ProdList: 672
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Wuhu Huaren Science and Technology Co., Ltd.

Tel: 0553-5842013-801 18155347026
Fax: 086-553-5843138
Email: jinhuaren@huarensh.com
Country: China
ProdList: 255
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4747
Advantage: 58

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

More

Less

View Lastest Price from 5-ETHYNYL-2'-DEOXYURIDINE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 5-ETHYNYL-2'-DEOXYURIDINE 61135-33-9
Price: US $0.00-0.00/G
Min. Order: 1G
Purity: 98%
Supply Ability: 2000
Release date: 2025-06-04

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Ethynyl-2'-deoxyuridine 61135-33-9
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 98%min
Supply Ability: 1000g
Release date: 2021-09-03

Henan Aochuang Chemical Co.,Ltd.

Product: 5-ETHYNYL-2'-DEOXYURIDINE 61135-33-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-27

61135-33-9, 5-ETHYNYL-2'-DEOXYURIDINERelated Search:

5-Ethynyl uridine Netivudine 5-ETHYNYL-2'-DEOXYURIDINE FLUORESCEIN-12-DUTP FLUORESCEIN-12-UTP CHROMATIDE(TM) TEXAS RED(R)-5-DUTP DIETHYLAMINOCOUMARIN-5-DUTP FLUORESCEIN CHLOROTRIAZINYL-4-UTP LISSAMINE-5-UTP CHROMATIDE(TM) BODIPY(R) 630/650-14-DUTP 5-PROPYNYL-2'-DEOXYURIDINE-5'-TRIPHOSPHATE LITHIUM SALT NAPHTHOFLUORESCEIN-5-DUTP CHROMATIDE(TM) BODIPY(R) 650/665-14-DUTP CHROMATIDE(TM) TEXAS RED(R)-5-UTP COUMARIN-5-DUTP LISSAMINE-5-DUTP COUMARIN-5-UTP TETRAMETHYLRHODAMINE-6-DDUTP

5-ETHYNYL-2'-DEOXYURIDINE

2’-deoxy-5-ethynyl-uridin

2’-deoxy-5-ethynyluridine

EYdU

5-Ethynyl-durd

Aids072372

Aids-072372

2'deoxyuridine, 5-ethynyl

Uridine,2

5-Ethynyl-2'-dU

EDU [5-Ethynyl-2'-deoxyuridine] *50 Mg*

Uridine,2'-deoxy-5-ethynyl-

5-Ethynyl-2'-deoxyuridine, (EdU) AldrichCPR

5-Ethynyl-2′-deoxyuridine, (EdU)

5-Ethynyl-2'-deoxyuridine 95%

5-Ethynyl-2'-deoxy-uridine (5-EdU)

5-E-dU

EdU(5-ethynyl-2'-deoxyuridine)

5-Ethynyl-dU

5-Ethynyl-2'-deoxyuridine &gt

abs9124

-deoxyuridine

5-Ethynyl-2'-deoxyuridine(EdU)

EdU, DNA synthesis monitoring probe

5-Ethynyl-2''-deoxyuridine

5-Ethynyl-2''-deoxyuridine, 10 mM in DMSO

EdU (5-Ethynyl-2′-deoxyuridine) (CCT-1149)

5-Ethynyl-2&#8242,-deoxyuridine (5-EdU) (100 mg)

5-Ethynyl-2&#8242,-deoxyuridine (5-EdU) (25 mg)

5-Ethynyl-2&#8242,-deoxyuridine (5-EdU) (5 g)

5-Ethynyl-2&#8242,-deoxyuridine (5-EdU) (500 mg)

61135-33-9

C11H12N2O5

SiChem