ChemicalBook > CAS DataBase List > 5-ETHYNYL-2'-DEOXYURIDINE

5-ETHYNYL-2'-DEOXYURIDINE

Product Name
5-ETHYNYL-2'-DEOXYURIDINE
CAS No.
61135-33-9
Chemical Name
5-ETHYNYL-2'-DEOXYURIDINE
Synonyms
abs9124;EYdU;5-E-dU;Uridine,2;Aids072372;Aids-072372;5-Ethynyl-dU;-deoxyuridine;5-Ethynyl-durd;5-Ethynyl-2'-dU
CBNumber
CB0243359
Molecular Formula
C11H12N2O5
Formula Weight
252.22
MOL File
61135-33-9.mol
More
Less

5-ETHYNYL-2'-DEOXYURIDINE Property

Melting point:
199°C(lit.)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO (up to 10 mg/ml).
pka
8.29±0.10(Predicted)
form 
powder
color 
White or off-white
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey
CDEURGJCGCHYFH-DJLDLDEBSA-N
CAS DataBase Reference
61135-33-9
More
Less

Safety

Hazard Codes 
T
Risk Statements 
46-61
Safety Statements 
53-45-24/25
RTECS 
YU7510000
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H340May cause genetic defects

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P308+P313IF exposed or concerned: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
900584
Product name
5-Ethynyl-2′-deoxyuridine
Purity
95%
Packaging
50mg
Price
$147
Updated
2024/03/01
Sigma-Aldrich
Product number
900584
Product name
5-Ethynyl-2′-deoxyuridine
Purity
95%
Packaging
500mg
Price
$1030
Updated
2024/03/01
TCI Chemical
Product number
E1057
Product name
5-Ethynyl-2'-deoxyuridine
Purity
>98.0%(HPLC)(T)
Packaging
50mg
Price
$89
Updated
2024/03/01
TCI Chemical
Product number
E1057
Product name
5-Ethynyl-2'-deoxyuridine
Purity
>98.0%(HPLC)(T)
Packaging
200mg
Price
$258
Updated
2024/03/01
Cayman Chemical
Product number
20518
Product name
5-Ethynyl-2'-deoxyuridine
Purity
≥98%
Packaging
50mg
Price
$44
Updated
2024/03/01
More
Less

5-ETHYNYL-2'-DEOXYURIDINE Chemical Properties,Usage,Production

Description

5-Ethynyl-2′-deoxyuridine (61135-33-9) is a novel agent for fast and sensitive detection of DNA synthesis?in vivo.1 5-EdU is incorporated into proliferating cells followed by detection with a fluorescent azide using click ligation.1 In contrast to the use of BrdU, the new method does not require sample fixation or DNA denaturation. 5-Ethynyl-2′-deoxyuridine may be used for studying cell proliferation in the central nervous system and may be combined with BrdU staining in a novel protocol allowing for double labeling of DNA synthesis.2

Uses

5-Ethynyl-2’deoxyuridine is a extensively used nucleoside analog used as a probe for DNA synthesis. However, 5-Ethynyl-2’deoxyuridine is a toxic anti-metabolite, which potentially causes DNA instabi liy, necrosis and cell-cycle arrest, therefore it is often used for short-term DNA synthesis in tissue culture and living organisms where prolonged cell survival is not required.

Uses

5-Ethynyl-2′-deoxyuridine (EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferation. It has an alkyne handle that can ligate with azide-containing fluorescent probes through a highly efficient click chemistry reaction. EdU nucleoside can be incorporated into the DNA of cells either in culture or in animals without showing significant toxicity. The assay offers a simpler workflow for detecting cell proliferation than anti-BrdU assays.

For information on Baseclick kits containing all the reagents for the assays see: Baseclick kits

For a listing of the Baseclick kits see: Baseclick kits

storage

Store at -20°C

References

1) Salic and Mitchison (2008),?A chemical method for fast and sensitive detection of DNA synthesis in vivo; Proc. Natl. Acad. Sci. USA,?105?2415 2) Zeng?et al. (2010),?Evaluation of 5-ethynyl-2′-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system; Brain Res.,?1319C?21

5-ETHYNYL-2'-DEOXYURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-ETHYNYL-2'-DEOXYURIDINE Suppliers

Wuhu Nuowei Chemical Technology Co., Ltd
Tel
0553-8233716 18055326116
Email
sales@nuowei-chem.com
Country
China
ProdList
951
Advantage
55
Maanshan geneyan biotech Co.,LTD
Tel
18913822354
Email
market@geneyan-bio.com
Country
China
ProdList
299
Advantage
58
Fuyang Ziyi Biological Pharmaceutical Co., Ltd.
Tel
19308655899
Fax
-
Email
2677609105@qq.com
Country
China
ProdList
468
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Hongene Biotech Corporation
Tel
021-64757213
Fax
86-21-64700613
Email
info@hongene.com
Country
China
ProdList
672
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Wuhu Huaren Science and Technology Co., Ltd.
Tel
0553-0553-0553-5842013-801-801 18155347026
Fax
086-553-5843138
Email
jinhuaren@huarensh.com
Country
China
ProdList
295
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9462
Advantage
58
Nanjing Baifuli Technology Co., Ltd.
Tel
25-25-58740604 15951658055
Fax
+86-25-58356858
Email
sales@unisyn.cn
Country
China
ProdList
561
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai XIYU Chemical Technology Co.,Ltd.
Tel
021-61052090 15221126179
Fax
021-38473230
Country
China
ProdList
368
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
BeiJing TOP Science Bio-Technology Co., Ltd.
Tel
+86-13439059536 +86-15201677815
Country
China
ProdList
291
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4943
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11481
Advantage
59
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Tianjin Scaxchem Limited Compnay
Tel
022-022-25327698 18920479040
Email
sales@cosychem.com
Country
China
ProdList
589
Advantage
55
Quzhou Rundong Chemical (Technology) Co.
Tel
0570-8789886 18892685668
Fax
0570-8789985
Email
info@rundongchemical.com
Country
China
ProdList
3970
Advantage
60
Struchem Co., Ltd.
Tel
0512-0512-63009836 15365350169
Fax
0512-63006936
Email
helen@struchem.com
Country
China
ProdList
3984
Advantage
60
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7980
Advantage
55
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Anhui kuer Bioengineering Co., Ltd
Tel
0551-65171243 13856024262
Email
kuer@kuerhuaxue.com
Country
China
ProdList
2997
Advantage
55
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-50664929, 13971561712
Fax
027-50664927 / QQ: 3452835437
Email
hubxys2001@163.com
Country
China
ProdList
1437
Advantage
55
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8025
Advantage
58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9355
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15818
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15497
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4824
Advantage
58
Wuhan Henruixintai Biological Co., Ltd.
Tel
027-027-65522215 18163303831
Fax
-
Email
360034463@qq.com
Country
China
ProdList
998
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
24969
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-010-010-62971590 18548936886
Fax
010-62340519
Email
jack@oka-vip.com
Country
China
ProdList
6897
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Cool Pharm, Ltd
Tel
18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
13010
Advantage
58
Hefei Bomei Biotechnology Co., Ltd.
Tel
13856598764
Email
531626407@qq.com
Country
China
ProdList
3007
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9639
Advantage
58
More
Less

View Lastest Price from 5-ETHYNYL-2'-DEOXYURIDINE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
5-Ethynyl-2'-deoxyuridine 61135-33-9
Price
US $0.00-0.00/g
Min. Order
10g
Purity
98%min
Supply Ability
1000g
Release date
2021-09-03
Xian confluore Biological Technology Co., Ltd.
Product
5-Ethynyl-2'-deoxyuridine 61135-33-9
Price
US $0.00/g
Min. Order
5g
Purity
>95.00%
Supply Ability
5g
Release date
2024-03-30
Henan Aochuang Chemical Co.,Ltd.
Product
5-ETHYNYL-2'-DEOXYURIDINE 61135-33-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27

61135-33-9, 5-ETHYNYL-2'-DEOXYURIDINERelated Search:


  • 5-ETHYNYL-2'-DEOXYURIDINE
  • 2’-deoxy-5-ethynyl-uridin
  • 2’-deoxy-5-ethynyluridine
  • EYdU
  • 5-Ethynyl-durd
  • Aids072372
  • Aids-072372
  • 2'deoxyuridine, 5-ethynyl
  • Uridine,2
  • 5-Ethynyl-2'-dU
  • EDU [5-Ethynyl-2'-deoxyuridine] *50 Mg*
  • Uridine,2'-deoxy-5-ethynyl-
  • 5-Ethynyl-2'-deoxyuridine, (EdU) AldrichCPR
  • 5-Ethynyl-2′-deoxyuridine, (EdU)
  • 5-Ethynyl-2'-deoxyuridine 95%
  • 5-Ethynyl-2'-deoxy-uridine (5-EdU)
  • 5-E-dU
  • EdU(5-ethynyl-2'-deoxyuridine)
  • 5-Ethynyl-dU
  • 5-Ethynyl-2'-deoxyuridine &gt
  • abs9124
  • -deoxyuridine
  • EdU(5-Ethynyl-2'-deoxyuridine)
  • 5-Ethynyl-2'-deoxyuridine(EdU)
  • 5-Ethynyl-2'-dU
  • 5-ETHYNYL-2'-DEOXYURIDINE
  • 61135-33-9
  • C11H12N2O5
  • SiChem