1-OCTADECYL LPA

Product Name: 1-OCTADECYL LPA
CAS No.: 52977-29-4
Chemical Name: 1-OCTADECYL LPA
Synonyms: 1-OCTADECYL LPA;1-OCTADECYL LYSOPHOSPHATIDIC ACID;1-Octadecyl Lysophosphatidic Acid Exclusive;1-Octadecyl Lysophosphatidic Acid (1-Octadecyl LPA);1,2-Propanediol, 3-(octadecyloxy)-, 1-(dihydrogen phosphate)
CBNumber: CB02455642
Molecular Formula: C21H45O6P
Formula Weight: 424.55
MOL File: 52977-29-4.mol

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1-OCTADECYL LPA Property

storage temp.: Store at -20°C
solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) ((1:1): 0.5 mg/ml
form: A crystalline solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10010164
Product name: 1-Octadecyl Lysophosphatidic Acid
Purity: ≥95%
Packaging: 500μg
Price: $26
Updated: 2024/03/01

Cayman Chemical

Product number: 10010164
Product name: 1-Octadecyl Lysophosphatidic Acid
Purity: ≥95%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 10010164
Product name: 1-Octadecyl Lysophosphatidic Acid
Purity: ≥95%
Packaging: 5mg
Price: $192
Updated: 2024/03/01

Cayman Chemical

Product number: 10010164
Product name: 1-Octadecyl Lysophosphatidic Acid
Purity: ≥95%
Packaging: 10mg
Price: $332
Updated: 2024/03/01

AK Scientific

Product number: 1374AH
Product name: 3-(Octadecyloxy)-1-(dihydrogenphosphate)-1,2-propanediol
Packaging: 10mg
Price: $440
Updated: 2021/12/16

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1-OCTADECYL LPA Chemical Properties,Usage,Production

Description

1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.^1,2 Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC₅₀ value of 9 nM versus 1-octadecanoyl LPA which has an EC₅₀ value of 177 nM.³

References

1. Noguchi, K., Ishii, S., and Shimizu, T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family J. Biol. Chem. 278(28),25600-25606(2003).
2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions Trends Cell Biol. 4(6),213-219(1994).
3. Tokumura, A., Sinomiya, J., Kishimoto, S., et al. Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids Biochem. J. 365,617-628(2002).

1-OCTADECYL LPA Preparation Products And Raw materials

Raw materials

Preparation Products

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1-OCTADECYL LPA Suppliers

China 17 United States 3 Global 20

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52977-29-4, 1-OCTADECYL LPARelated Search:

1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Distearoyl-sn-glycero-3-phosphocholine Phosphatidylserine 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-OCTADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE 1,2-DIACYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT 1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Distearoyl-sn-glycero-3-phosphoglycerol,sodium salt L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL 1,2-DIDOCOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIOCTADECANOYL-SN-GLYCERO-3-PHOSPHO-RAC-[1-GLYCEROL] AMMONIUM SALT 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATIDIC ACID DISODIUM SALT 1,2-DISTEAROYL-RAC-GLYCERO-3-PHOSPHOCHOLINE PAF (C18) 3-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-1-PHOSPHOCHOLINE

1-OCTADECYL LPA

1-OCTADECYL LYSOPHOSPHATIDIC ACID

1-Octadecyl Lysophosphatidic Acid Exclusive

1,2-Propanediol, 3-(octadecyloxy)-, 1-(dihydrogen phosphate)

1-Octadecyl Lysophosphatidic Acid (1-Octadecyl LPA)

52977-29-4