ChemicalBook > CAS DataBase List > QUINAPRILAT HYDRATE

QUINAPRILAT HYDRATE

Product Name
QUINAPRILAT HYDRATE
CAS No.
82768-85-2
Chemical Name
QUINAPRILAT HYDRATE
Synonyms
CI-92;ci928;quinaprilat;quinaprilate;Quinapril USP RC B;QUINAPRILAT HYDRATE;Quinapril EP Impurity C;Quinapril USP impurity B;Quinapril Related CoMpound B;Quinapril USP Related CoMpound B
CBNumber
CB0247832
Molecular Formula
C23H26N2O5
Formula Weight
410.46
MOL File
82768-85-2.mol
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QUINAPRILAT HYDRATE Property

Melting point:
166-1680C
alpha 
D23 +20.9° (c = 1 in methanol)
Boiling point:
674.5±55.0 °C(Predicted)
Density 
1.289±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO: ≥23mg/mL
form 
powder
pka
2.19±0.10(Predicted)
color 
white to tan
optical activity
[α]/D +16 to +23 (C=1, MeOH)
CAS DataBase Reference
82768-85-2
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Safety

Hazard Codes 
T,N
Risk Statements 
25-50
Safety Statements 
45-61
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HS Code 
2933492250
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1593423
Product name
Quinapril Related Compound B
Packaging
50mg
Price
$596
Updated
2024/03/01
TRC
Product number
Q670010
Product name
Quinaprilat
Packaging
10mg
Price
$130
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005945
Product name
QUINAPRILAT HYDRATE
Purity
95.00%
Packaging
5MG
Price
$503.2
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
13313
Product name
Quinaprilat
Packaging
50mg
Price
$2000
Updated
2021/12/16
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QUINAPRILAT HYDRATE Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

Quinaprilat (Quinapril EP Impurity C) is a metabolite of Quinapril, an angiotensin converting enzyme (ACE) inhibitor.

Definition

ChEBI: Quinaprilat is a dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a vasodilator agent. It is a dicarboxylic acid, a member of isoquinolines and a tertiary carboxamide.

QUINAPRILAT HYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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82768-85-2, QUINAPRILAT HYDRATERelated Search:

[2H5]-Quinapril QUINAPRIL RELATED COMPOUND A (50 MG) (ETHYL[3S-[2(R*),3A,11A BETA]]-1,3,4,6,11,11A-HEXAHYDRO-3-METHYL-1,4-DIOXO-ALPHA-(2-PHENY-LETHYL)-2H-PYRAZINO[1,2-B]ISOQUINOLINE-2-ACETATE) CarboxylicAcidPhenylMethylEsterHydrochloride,QuinaprilHcl [3S-[2[R*(R*)],3R*]]-2-[2-[[1-(Ethoxycarbonyl)-3-phenylpropyl]aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid Ethyl Ester (2Z)-2-Butenedioate Quinapril hydrochloride EP impurity G Quinapril (3S)-3,4-Dihydro-2-[(2S)-2-[[(1S)-1-[(1-Methylethoxy)carbonyl]-3-phenylpropyl]aMino]-1-oxopropyl]-3(1H)-isoquinolinecarboxylic Acid IBBLRJGOOANPTQ-GOMJJGCLSA-N Quinapril Cyclohexyl Analog Quinaprilat-D5 QUINAPRILAT HYDRATE MOEXIPRILAT HYDRATE Quinapril hydrochloride Moexipril (S)-2-[(S)-2-((S)-1-Ethoxycarbonyl-3-phenylpropylamino)propionyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid benzyl ester Quinapril benzyl ester maleate MOEXIPRILAT-D5 QUINAPRIL-D5, HYDROCHLORIDE

  • quinaprilat
  • (3S)-2-[(S)-2-[[(S)-1-Carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  • (3S)-2-[(S)-2-[[(S)-1-Carboxy-3-phenylpropyl]amino]propionyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  • Quinapril Related Compound B (50 mg) (3-Isoquinolinecarboxylic acid, 2-[2-[(1-carboxy-3-phenylpropyl)amino]-1-oxopropyl]-1,2,3,4-tetrahydro-,[3S-[2[R*(R*)],3R*]]-)
  • Quinapril USP Related CoMpound B
  • Quinapril Related CoMpound B
  • (3S)-2-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid
  • CI-92
  • 3-Isoquinolinecarboxylic acid, 2-(2S)-2-(1S)-1-carboxy-3-phenylpropylamino-1-oxopropyl-1,2,3,4-tetrahydro-, (3S)-
  • QUINAPRILAT HYDRATE
  • (3S)-2-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrate
  • Quinapril USP RC B
  • Quinapril Impurity 3（Quinapril EP Impurity C）
  • (3S)-2-[(2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  • quinaprilate
  • Quinapril EP Impurity C
  • (3s-(2(r*(r*)),3r*))-yl)amino)-1-oxopropyl)
  • 3-isoquinolinecarboxylicacid,1,2,3,4-tetrahydro-2-(2-((1-carboxy-3-phenylprop
  • ci928
  • [3S-[2[R*(R*)],3R*]]-2-[2-[(1-Carboxy-3-phenylpropyl)amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
  • Quinapril USP impurity B
  • Quinapril EP Impurity C/ Quinapril Related Compound B (Quinaprilat/ Quinapril Diacid)
  • (S)-2-(((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  • Quinapril Related Compound B(Secondary Standards traceble to USP)
  • QuinaprilatQ: What is Quinaprilat Q: What is the CAS Number of Quinaprilat Q: What is the storage condition of Quinaprilat Q: What are the applications of Quinaprilat
  • Quinapril Related Compound B (3-Isoquinolinecarboxylic acid, 2-[2-[(1-carboxy-3-phenylpropyl)amino] (1593423)
  • Quinapril Hydrochloride Impurity C
  • Quinapril Hydrochloride EP Impurity C
  • Quinapril EP Impurity C (Quinapril USP Related Compound B, Quinaprilat)
  • Quinaprilat (Quinapril impurity C)
  • 82768-85-2
  • Various Metabolites and Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals