ChemicalBook > CAS DataBase List > 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
- Product Name
- 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
- CAS No.
- 145100-51-2
- Chemical Name
- 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
- Synonyms
- Comins;N-(5-CHLORO-2-PYRIDYL)TRIFLIMIDE;N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-;N-(5-CHLORO-2-PYRIDYL)BIS(TRIFLUOROMETHANESULFONIMIDE);N,N-BIS(TRIFLUOROMETHYLSULFONYL)-5-CHLORO-2-PYRIDYLAMINE;2-[N,N-BIS(TRIFLUOROMETHYLSULPHONYL)AMINO]-5-CHLOROPYRIDINE;N-(5-Chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide;Comins'reagent;Comins Triflating Reagent;N-(5-Chloropyridin-2-yl)triflimide
- CBNumber
- CB0248253
- Molecular Formula
- C7H3ClF6N2O4S2
- Formula Weight
- 392.68
- MOL File
- 145100-51-2.mol
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2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Property
- Melting point:
- 45-47 °C(lit.)
- Boiling point:
- 77-90°C/0.2mmHg
- Density
- 1.892±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Benzene (Slightly)
- form
- Solid
- pka
- -7.71±0.10(Predicted)
- color
- yellow
- Water Solubility
- Reacts with water.
- Sensitive
- Moisture Sensitive
- BRN
- 5833971
- Stability:
- Moisture Sensitive, Unstable in DMSO Solution
- InChIKey
- TUFGVZMNGTYAQD-UHFFFAOYSA-N
- CAS DataBase Reference
- 145100-51-2(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 403644
- Product name
- N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)
- Purity
- 96%
- Packaging
- 1g
- Price
- $28.7
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 403644
- Product name
- N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide)
- Purity
- 96%
- Packaging
- 5g
- Price
- $127
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B1865
- Product name
- 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent]
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $83
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B1865
- Product name
- 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine [Triflating Reagent]
- Purity
- >96.0%(GC)
- Packaging
- 25g
- Price
- $412
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L16929
- Product name
- 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 99%
- Packaging
- 1g
- Price
- $37.65
- Updated
- 2024/03/01
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2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Chemical Properties,Usage,Production
Chemical Properties
White to pale yellow crystalline solid
Uses
2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuki-Miyaura cross coupling, synthesis of nicotinic acetylcholine receptor-selective ligands, enantioselective desymmetrizing palladium catalyzed carbonylation reactions, synthesis of high affinity niacin receptor GPR109A agonists and in preparation of heteroaromatics.
Uses
Reactant for:
Suzuki-Miyaura cross coupling
Synthesis of nicotinic acetylcholine receptor-selective ligands
Enantioselective desymmetrizing palladium catalyzed carbonylation reactions
Synthesis of high affinity niacin receptor GPR109A agonists
Preparation of heteroaromatics
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
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View Lastest Price from 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE manufacturers
Hebei Weibang Biotechnology Co., Ltd
- Product
- 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE 145100-51-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-11
Zibo Hangyu Biotechnology Development Co., Ltd
- Product
- 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE 145100-51-2
- Price
- US $50.00-500.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-31
Hebei Mojin Biotechnology Co., Ltd
- Product
- 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE 145100-51-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-17
145100-51-2, 2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINERelated Search:
Mesitylene-2-sulfonyl chloride
2-[N,N-BIS(TRIFLUOROMETHYLSULFONYL)AMINO]PYRIDINE
2-Amino-5-chloropyridine
Trifluoromethanesulfonamide
2-[N,N-BIS(TRIFLUOROMETHANESULFONYL)AMINO]-5-CHLOROPYRIDINE
Trifluoromethanesulfonimide