Massoniaside B
- Product Name
- Massoniaside B
- CAS No.
- 188300-19-8
- Chemical Name
- Massoniaside B
- Synonyms
- Massoniaside B;Massonianoside B;α-L-Mannopyranoside, 4-[(2S,3R)-2,3-dihydro-7-hydroxy-3-(hydroxymethyl)-5-(3-hydroxypropyl)-2-benzofuranyl]-2-methoxyphenyl 6-deoxy
- CBNumber
- CB02519849
- Molecular Formula
- C25H32O10
- Formula Weight
- 492.52
- MOL File
- 188300-19-8.mol
Massoniaside B Property
- Boiling point:
- 708.9±60.0 °C(Predicted)
- Density
- 1.406±0.06 g/cm3(Predicted)
- storage temp.
- -10 to -25°C
- solubility
- DMSO: 2mg/mL, clear
- pka
- 9.91±0.60(Predicted)
- form
- powder
- color
- white to beige
Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FM167217
- Product name
- Massonianoside B
- Packaging
- 5mg
- Price
- $750
- Updated
- 2021/12/16
- Product number
- FM167217
- Product name
- Massonianoside B
- Packaging
- 10mg
- Price
- $1200
- Updated
- 2021/12/16
- Product number
- W1836
- Product name
- MassonianosideB
- Packaging
- 10mg
- Price
- $1670
- Updated
- 2021/12/16
- Product number
- CFN99869
- Product name
- MassonianosideB
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $553
- Updated
- 2021/12/16
Massoniaside B Chemical Properties,Usage,Production
Uses
Massonianoside B can be used for pharmaceutical compositions as active ingredient to prevent and treat mixed lineage leukemia rearranged leukemia.
Biological Activity
Massonianoside B is a cell-permeable, potent, highly selective, reversible and SAM-competitive DOT1L (disruptor of 4 telomeric silencing 1-like) inhibitor th at decreases cellular levels of H3K79 methylation and inhibits the MLL fusion target genes HOXA9 and MEIS1 expression. Massonianoside B exhibits anti-leukemic activity. It is metabolically stable in both human and mouse liver microsomes.
Massoniaside B Preparation Products And Raw materials
Raw materials
Preparation Products
Massoniaside B Suppliers
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