Neostenine

Product Name: Neostenine
CAS No.: 477953-07-4
Chemical Name: Neostenine
Synonyms: Neostenine;Furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10(2H)-one, 8-ethyldodecahydro-11-methyl-, (7aR,8R,8aR,11S,11aR,11bS,11cR)-
CBNumber: CB02519894
Molecular Formula: C17H27NO2
Formula Weight: 277.4
MOL File: 477953-07-4.mol

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Neostenine Property

Boiling point:: 414.6±45.0 °C(Predicted)
Density: 1.12±0.1 g/cm3(Predicted)
pka: 9.93±0.60(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN98725
Product name: Neostenine
Packaging: 5mg
Price: $643
Updated: 2021/12/16

Crysdot

Product number: CD32001328
Product name: Neostenine
Purity: 95+%
Packaging: 5mg
Price: $998
Updated: 2021/12/16

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Neostenine Chemical Properties,Usage,Production

Uses

Neostenine is a stenine-type Stemona alkaloid, with antitussive activity. Neostenine is also a substrate of P-glycoprotein with high absorptive permeability in Caco-2 monolayer model. Neostenine also shows oral activity for intestinal application[1][2].

References

[1] Chung HS, et al. Antitussive activity of Stemona alkaloids from Stemona tuberosa. Planta Med. 2003 Oct;69(10):914-20. DOI:10.1055/s-2003-45100
[2] Leung PH, et al. Intestinal absorption of Stemona alkaloids in a Caco-2 cell model. Planta Med. 2006 Feb;72(3):211-6. DOI:10.1055/s-2005-916195

Neostenine Preparation Products And Raw materials

Raw materials

Preparation Products

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Neostenine

Furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10(2H)-one, 8-ethyldodecahydro-11-methyl-, (7aR,8R,8aR,11S,11aR,11bS,11cR)-

477953-07-4