Description References
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Tributyltin chloride

Description References
Product Name
Tributyltin chloride
CAS No.
1461-22-9
Chemical Name
Tributyltin chloride
Synonyms
TRIBUTYLTIN CHLORIDE;tributylchlorostannane;TRI-N-BUTYLTIN CHLORIDE;TBTC;TBTCL;Tributylzinnchlorid;Tributylstannyl chloride;N-TRI-TERT-BUTYLTIN CHLORIDE;wr3396;WR 3396
CBNumber
CB0262161
Molecular Formula
C12H27ClSn
Formula Weight
325.51
MOL File
1461-22-9.mol
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Tributyltin chloride Property

Melting point:
-9 °C
Boiling point:
171-173 °C25 mm Hg(lit.)
Density 
1.2 g/mL at 25 °C(lit.)
vapor pressure 
<0.01 mm Hg ( 20 °C)
refractive index 
n20/D 1.492(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
0.017g/l
form 
liquid
Specific Gravity
1.186
color 
colorless
Water Solubility 
PRACTICALLY INSOLUBLE
Sensitive 
Moisture Sensitive
BRN 
3535715
Exposure limits
ACGIH: TWA 0.1 mg/m3; STEL 0.2 mg/m3 (Skin)
NIOSH: IDLH 25 mg/m3; TWA 0.1 mg/m3
Stability:
Hygroscopic
InChIKey
GCTFWCDSFPMHHS-UHFFFAOYSA-M
LogP
2.21 at 23℃
CAS DataBase Reference
1461-22-9(CAS DataBase Reference)
NIST Chemistry Reference
Tri-n-butyltin chloride(1461-22-9)
EPA Substance Registry System
Tributyltin chloride (1461-22-9)
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Safety

Hazard Codes 
T,N
Risk Statements 
21-25-36/38-48/23/25-50/53
Safety Statements 
35-36/37/39-45-60-61-26
RIDADR 
UN 2788 6.1/PG 3
WGK Germany 
3
RTECS 
WH6820000
3-9-21
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29310095
Hazardous Substances Data
1461-22-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H312Harmful in contact with skin

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T50202
Product name
Tributyltin chloride
Purity
96%
Packaging
5g
Price
$43.9
Updated
2024/03/01
Sigma-Aldrich
Product number
442869
Product name
Tributyltin chloride
Purity
analytical standard
Packaging
500mg
Price
$83.5
Updated
2024/03/01
Sigma-Aldrich
Product number
45713
Product name
TBTC
Purity
PESTANAL
Packaging
250mg
Price
$45.6
Updated
2022/05/15
Alfa Aesar
Product number
A10746
Product name
Tri-n-butyltin chloride, 96%
Packaging
50g
Price
$58.4
Updated
2023/06/20
Alfa Aesar
Product number
A10746
Product name
Tri-n-butyltin chloride, 96%
Packaging
250g
Price
$209
Updated
2023/06/20
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Tributyltin chloride Chemical Properties,Usage,Production

Description

Tributyltin chloride is also as Chlorotributyltin, is the chloride of tributyltin. It is a biocide that contaminates foods, especially shellfish. It is an endocrine disrupter in several marine species and is neurotoxic and immuno-toxic in mammals. It has been used as a heat stabilizer, agricultural pesticide and component of antifouling paints2. However, it is perhaps the most acutely toxic chemical to aquatic organisms ever deliberately introduced to water. It has been demonstrated to have an adverse effect on shellfish in France and England, and as a consequence the use of tributyltin‐containing antifouling paints has been restricted in these countries. Other countries have banned the use of tributyltin‐containing antifouling paints or are contemplating restrictions3.

References

  1. Cooke, G. M., et al. Food & Chemical Toxicology An International Journal Published for the British Industrial Biological Research Association 42.2(2004):211-220.
  2. Nakatsu, Yusuke, Y. Kotake, and S. Ohta. "Tributyltin-induced cell death is mediated by calpain in PC12 cells."Neurotoxicology 27.4(2006):587-593.
  3. Maguire, R. James. "Environmental aspects of tributyltin." Applied Organometallic Chemistry 1.6(1987):475-498.

Chemical Properties

Colorless or light yellow clear liquid. Soluble in the common organic solvents; including alcohol, heptane, benzene, and toluene; insoluble in cold water, but hydrolyzes in hot water.

Uses

Tributyltin Chloride is a triorganotin compound with insecticidal acitivity. It is an endocrine disruptor as well as an inhibitor for the V-ATPases (potential targets in the treatmen t of diseases such as osteoporosis and cancer). Tributyltin Chloride has the functions of antiseptic, sterilization and mildew proof and widely used in wood preservation, ship paint, etc. Further, it is used in hot end glass coating and rodent-repellent for cable coatings.

Preparation

Tributyltin chloride is prepared by a redistribution reaction by combining stannic chloride and tetrabutyltin:
3 (C4H9)4Sn + SnCl4 → 4 (C4H9)3SnCl.

Definition

ChEBI: Tributyltin chloride is an inorganic molecular entity.

Hazard

A poison by ingestion and skin contact. A severe eye irritant. Tributyl tin compounds are extremely toxic to marine life.

Flammability and Explosibility

Not classified

Toxicology

Tributyltin chloride (TBTCL) is a widely used biocide and heat stabiliser for PVC compositions. TBTCL has been detected in humans and may cause harmful effects on the thyroid, cardiovascular and other organs in humans. It is also an endocrine disruptor with toxic effects on the male reproductive system.TBTCL causes apoptosis and cell cycle arrest. Activation of endoplasmic reticulum stress and inhibition of autophagy are responsible for TBTCL-induced apoptosis and cell cycle arrest. 

Tributyltin chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Tributyltin chloride Suppliers

Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
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58
Terma Medicare India Pvt.,Ltd
Tel
+8613916485955
Email
shivshanghai@yahoo.com
Country
India
ProdList
150
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58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
VASIN BIO LIFE SCIENCES PVT LTD
Tel
--
Fax
--
Email
info@vasinbio.com
Country
India
ProdList
2092
Advantage
58
I K Construction Chemicals
Tel
--
Fax
--
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India
ProdList
1
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58
Infinity Speciality Chemicals
Tel
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Fax
--
Country
India
ProdList
12
Advantage
58
Neha Chemicals
Tel
--
Fax
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Country
India
ProdList
6
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58
YMS Laboratories Private Limited
Tel
--
Fax
--
Country
India
ProdList
15
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58
Foxkem Industries
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--
Fax
--
Country
India
ProdList
120
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58
Malik Polychem Limited
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Fax
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India
ProdList
1
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58
S V Plastochem Private Limited
Tel
--
Fax
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India
ProdList
11
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58
Central Drug House(P) Ltd.
Tel
--
Fax
--
Email
sales@cdhfinechemical.com
Country
India
ProdList
6157
Advantage
58
LOBA CHEMIE PVT.LTD.
Tel
--
Fax
--
Email
info@lobachemie.com
Country
India
ProdList
3075
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58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
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58
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View Lastest Price from Tributyltin chloride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Chlorotributyltin 1461-22-9
Price
US $9.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-10-24
Hebei Mojin Biotechnology Co., Ltd
Product
Chlorotributyltin 1461-22-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
Chlorotributyltin 1461-22-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

1461-22-9, Tributyltin chlorideRelated Search:


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