ChemicalBook > CAS DataBase List > AKT Kinase Inhibitor
AKT Kinase Inhibitor
- Product Name
- AKT Kinase Inhibitor
- CAS No.
- 842148-40-7
- Chemical Name
- AKT Kinase Inhibitor
- Synonyms
- 3-[2-(4-amino-1;5-c]pyridin-4-yl]-;AKT Kinase Inhibito;AKT Kinase Inhibitor;AKT Kinase Inhibitor USP/EP/BP;AKT Kinase Inhibitor, 10 mM in DMSO;5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4;3-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-propyn-1-ol;2-Propyn-1-ol, 3-[2-(4-aMino-1,2,5-oxadiazol-3-yl)-7-(3-aMinopropoxy)-1-ethyl-1H-iMidazo[4,5-c]pyridin-4-yl]-;AKT Kinase Inhibitor (2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-)
- CBNumber
- CB02624073
- Molecular Formula
- C16H19N7O3
- Formula Weight
- 357.37
- MOL File
- 842148-40-7.mol
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AKT Kinase Inhibitor Property
- Boiling point:
- 678.8±65.0 °C(Predicted)
- Density
- 1.50
- storage temp.
- Store at -20°C
- solubility
- DMSO : 16.67 mg/mL (46.65 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
- form
- Powder
- pka
- 12.98±0.10(Predicted)
- color
- White to light yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0528
- Product name
- AKTKinaseInhibitor
- Purity
- 98.37%
- Packaging
- 5mg
- Price
- $420
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0292909
- Product name
- 3-[2-(4-AMINO-1,2,5-OXADIAZOL-3-YL)-7-(3-AMINOPROPOXY)-1-ETHYL-1H-IMIDAZO-[4,5-C]PYRIDIN-4-YL]-2-PROPYN-1-OL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.08
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0528
- Product name
- AKTKinaseInhibitor
- Purity
- 98.37%
- Packaging
- 10mg
- Price
- $720
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611707
- Product name
- AKT Kinase Inhibitor
- Packaging
- 10mg
- Price
- $734.4
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31000662
- Product name
- AKTKinaseInhibitor
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $245
- Updated
- 2021/12/16
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AKT Kinase Inhibitor Chemical Properties,Usage,Production
Uses
AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity[1].
Biological Activity
AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity.
in vivo
Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus.
target
| Akt
|
References
[1] Saverio Alberti, et al. Use of trop-2 as predictive marker of response to anti-tumor therapy based on inhibitors of cd9, akt and molecules of the tetraspanin signalling network. WO2013171777A2.
AKT Kinase Inhibitor Preparation Products And Raw materials
Raw materials
Preparation Products
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AKT Kinase Inhibitor Suppliers
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View Lastest Price from AKT Kinase Inhibitor manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- AKT Kinase Inhibitor 842148-40-7
- Price
- US $2.00-6.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-ton
- Release date
- 2025-07-28
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