ChemicalBook > CAS DataBase List > N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine

N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine

Product Name
N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
CAS No.
1260614-73-0
Chemical Name
N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
Synonyms
Tofatinib Impurity 18;Tofacitinib IMpurity N;Tofacitinib Impurity (N-Des-(2-Cyanide-acetyl)-(3S,4S));N-Methyl-N-[(3S,4S)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine;7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3S,4S)-4-Methyl-3-piperidinyl]-
CBNumber
CB02642727
Molecular Formula
C13H19N5
Formula Weight
245.32
MOL File
1260614-73-0.mol
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N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine Property

Melting point:
156-160°C
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
pka
13.36±0.50(Predicted)
form 
Solid
color 
Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
467698
Product name
Tofacitinib impurity N
Packaging
1mg
Price
$312
Updated
2021/12/16
TRC
Product number
T528020
Product name
TofacitinibimpurityN
Packaging
10mg
Price
$350
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0031939
Product name
N-METHYL-N-((3S,4S)-4-METHYLPIPERIDIN-3-YL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
Purity
95.00%
Packaging
5MG
Price
$495.2
Updated
2021/12/16
Crysdot
Product number
CD11312698
Product name
N-Methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Purity
95+%
Packaging
100mg
Price
$587
Updated
2021/12/16
Crysdot
Product number
CD11312698
Product name
N-Methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Purity
95+%
Packaging
250mg
Price
$939
Updated
2021/12/16
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N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine Chemical Properties,Usage,Production

Uses

Tofacitinib impurity N is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.

N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine Suppliers

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1260614-73-0, N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMineRelated Search:

Tofacitinib (3S,4S)-1-benzyl-N,4-diMethylpiperidin-3-aMine Tofacitinib related coMpound 2 3-((3S,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile (3R,4R)-N,1,4-trimethyl-N-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidin-3-amine Tofacitinib Impurity 19 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 3-((3R,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanaMide 6,7-Dihydro-N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-5H-pyrrolo[2,3-d]pyrimidin-4-amine R-afatinib Tofacitinib Impurity 20 (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine (3R,4R)-3-[(6-amino-4-pyrimidinyl)methylamino]-4-methyl-β-oxo-1-Piperidinepropanenitrile (3R,4R)-N,4-dimethyl-piperidin-3-amine TF-A 2-amino-4-fluoro-5-nitrobenzoic acid Ethyl S-4-chloro-3-hydroxybutyrate Tofacitinib Impurity T

  • 7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3S,4S)-4-Methyl-3-piperidinyl]-
  • N-Methyl-N-[(3S,4S)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • Tofacitinib IMpurity N
  • Tofacitinib Impurity (N-Des-(2-Cyanide-acetyl)-(3S,4S))
  • Tofatinib Impurity 18
  • 1260614-73-0