ChemicalBook > CAS DataBase List > 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine

Product Name
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
CAS No.
623950-02-7
Chemical Name
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
Synonyms
EOS-61912;Eluxadoline int1;Eluxadoline Intermediate 2;L-Phenylalanine propionic acid;4-(aminocarbonyl)-N-[(1,1-dimethylethoxy);4'-Carbamoyl N-Boc-2',6'-dimethyl-L-Phenylalanine;4-(Aminocarbonyl)-N-Boc-2,6-dimethyl-L-phenylalanine;4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimet...;(S)-2-(Boc-Amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic Acid;(S)-2-(N-BOC-amino)-3-(4-formamido-2,6-dimethylphenyl)propanoic acid
CBNumber
CB02651374
Molecular Formula
C17H24N2O5
Formula Weight
336.38
MOL File
623950-02-7.mol
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4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Property

Melting point:
>210℃
Boiling point:
497.1±45.0 °C(Predicted)
Density 
1.201
storage temp. 
2-8°C
pka
3.88±0.17(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C17H24N2O5/c1-9-6-11(14(18)20)7-10(2)12(9)8-13(15(21)22)19-16(23)24-17(3,4)5/h6-7,13H,8H2,1-5H3,(H2,18,20)(H,19,23)(H,21,22)/t13-/m0/s1
InChIKey
ZLUHLTMMROGKKD-ZDUSSCGKSA-N
SMILES
C(O)(=O)[C@H](CC1=C(C)C=C(C(N)=O)C=C1C)NC(OC(C)(C)C)=O
CAS DataBase Reference
623950-02-7
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B619640
Product name
(S)-2-(Boc-Amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoicAcid
Packaging
250mg
Price
$345
Updated
2021/12/16
Activate Scientific
Product number
AS46561
Product name
(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid
Purity
98% ee
Packaging
5G
Price
$358
Updated
2021/12/16
AK Scientific
Product number
0060AP
Product name
(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoicacid;
Packaging
10g
Price
$387
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0017695
Product name
4-(AMINOCARBONYL)-N-[(1,1-DIMETHYLETHOXY)CARBONYL]-2,6-DIMETHYL-L-PHENYLALANINE
Purity
95.00%
Packaging
5MG
Price
$495.7
Updated
2021/12/16
AK Scientific
Product number
0060AP
Product name
(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoicacid;
Packaging
25g
Price
$522
Updated
2021/12/16
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4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Chemical Properties,Usage,Production

Description

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine is a phenylalanine derivative. It is mainly used as a pharmaceutical intermediate component in the preparation of opioid modulators and eluxadoline.

Uses

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine is an intermediate used to prepare potential Dual delta-opioid antagonist/μ-opioid agonist used in the treatment of diarrhea. Irritable bowel syndrome.

4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine Suppliers

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View Lastest Price from 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine 623950-02-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine 623950-02-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine 623950-02-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

623950-02-7, 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanineRelated Search:

BOC-ALA-GLY-OH TERT-BUTYL N-ALLYLCARBAMATE Boc-D-aspartic acid 4-benzyl ester BOC-D-ALPHA-T-BUTYLGLYCINE Boc-L-aspartic acid 4-tert-butyl ester TERT-BUTOXY ACETIC ACID (BOC-AMINOOXY)ACETIC ACID BOC-BETA-TBU-D-ALA-OH 4-(PYRIDIN-2-YL)AMINOCARBONYLPHENYLBORONIC ACID

  • (2S)-3-(4-carbamoyl-2,6-dimethylphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
  • L-Phenylalanine, 4-(aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-
  • (2S)-2{[(tert-butoxy)carbonyl]amino}-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid
  • (S)-2-(N-BOC-amino)-3-(4-formamido-2,6-dimethylphenyl)propanoic acid
  • (S)-2-(tert-butoxycarbonylaMino)-3-(4-carbaMoyl-2,6-diMethylphenyl)propanoic aci
  • 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine###NA
  • 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
  • (s)-2-(tert-butoxycarbonylaMino)-3-(4-carbaMoyl-2,6-diMethylphenyl)propanoic acid
  • EOS-61912
  • Eluxadoline Intermediate 2
  • (S)-2-(Boc-Amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic Acid
  • L-Phenylalanine propionic acid
  • Eluxadoline: 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine
  • Eluxadoline int1
  • (S,E)-2-((tert-butoxy(hydroxy)methylene)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid
  • 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimet...
  • 4-(aminocarbonyl)-N-[(1,1-dimethylethoxy)
  • 4'-Carbamoyl N-Boc-2',6'-dimethyl-L-Phenylalanine
  • 4-(Aminocarbonyl)-N-Boc-2,6-dimethyl-L-phenylalanine
  • (S)-2-tert-Butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionic acid
  • 623950-02-7