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Methyl gallate

Product Name
Methyl gallate
CAS No.
99-24-1
Chemical Name
Methyl gallate
Synonyms
METHYL 3,4,5-TRIHYDROXYBENZOATE;GALLIC ACID METHYL ESTER;GALLICIN;Gallincin;methyl galloate;NSC 363001;AKOS 217-13;METHYGALLATE;METHYL GALLATE;MethylGallate>
CBNumber
CB0265566
Molecular Formula
C8H8O5
Formula Weight
184.15
MOL File
99-24-1.mol
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Methyl gallate Property

Melting point:
201-204 °C
Boiling point:
278.08°C (rough estimate)
Density 
1.3840 (rough estimate)
refractive index 
1.5690 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
ethanol: 50 mg/mL, clear
form 
Crystalline Powder
pka
8.04±0.23(Predicted)
color 
White to slightly beige
Water Solubility 
SOLUBLE IN HOT WATER
Merck 
14,4345
BRN 
2113180
InChIKey
FBSFWRHWHYMIOG-UHFFFAOYSA-N
LogP
0.860
CAS DataBase Reference
99-24-1(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 3,4,5-trihydroxy-, methyl ester (99-24-1)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-43
Safety Statements 
26-36/37-24/25
WGK Germany 
3
RTECS 
LW8000000
TSCA 
Yes
HS Code 
29182900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
274194
Product name
Methyl 3,4,5-trihydroxybenzoate
Purity
98%
Packaging
5g
Price
$25.86
Updated
2024/03/01
Sigma-Aldrich
Product number
274194
Product name
Methyl 3,4,5-trihydroxybenzoate
Purity
98%
Packaging
100g
Price
$105
Updated
2024/03/01
TCI Chemical
Product number
G0017
Product name
Methyl Gallate
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$25
Updated
2024/03/01
TCI Chemical
Product number
G0017
Product name
Methyl Gallate
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$77
Updated
2024/03/01
Alfa Aesar
Product number
L05926
Product name
Methyl 3,4,5-trihydroxybenzoate, 98%
Packaging
50g
Price
$48.65
Updated
2024/03/01
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Methyl gallate Chemical Properties,Usage,Production

Description

Methyl gallate is a phenolic compound found in Terminalia myriocarpa and Geranium niveum. It is also found in wine.
It is the methyl ester of gallic acid.

Description

Methyl gallate is a phenol that has been found in Meliaceae and has diverse biological activities. It reduces adipogenic hormonal stimulation-induced lipid accumulation in 3T3-L1 cells when used at a concentration of 50 μM. Methyl gallate is active against V. cholerae in vitro (MIC = 32 μg/ml) and reduces V. cholerae-induced intestinal fluid accumulation in suckling mice when administered at doses of 50, 100, and 200 mg/kg. It reduces tumor growth and decreases the number of intratumor CD25+Foxp3high regulatory T cells (Tregs) in an EL-4 model of murine lymphoma. Methyl gallate (0.7, 7, and 70 mg/kg) reduces knee joint edema and leukocyte, neutrophil, and mononuclear cell infiltration in a mouse model of zymosan-induced arthritis.

Chemical Properties

white to slightly beige crystalline powder

Uses

Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells.

Uses

Methyl 3,4,5-trihydroxybenzoate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells.

Uses

The gallate ester methyl gallate is used as an antioxidant. A ease was reported using a reprography paper.

Definition

ChEBI: Methyl 3,4,5-trihydroxybenzoate is a gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties. It has a role as a plant metabolite, an anti-inflammatory agent and an antioxidant.

Contact allergens

This ester of gallic acid is used as an antioxidant agent. A case was reported by using a reprography paper.

Purification Methods

Methyl gallate [99-24-1] M 184.2, m 202o. Crystallise the gallate ester from MeOH. [Beilstein 10 IV 1998.]

Methyl gallate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyl gallate manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
Methyl gallate 99-24-1
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000kg
Release date
2024-05-17
Hebei Weibang Biotechnology Co., Ltd
Product
Methyl gallate 99-24-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Hebei Yanxi Chemical Co., Ltd.
Product
Methyl Gallate 99-24-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100tons
Release date
2024-06-19

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  • Alphabetic
  • Analytical Chromatography Product Catalog
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  • Aromatic Esters
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