Cetirizine Ethyl Ester (USP RC A) Property

Boiling point:

519.9±45.0 °C(Predicted)

Density 

1.170±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

6.55±0.10(Predicted)

form 

Oil

color 

Pale Yellow to Dark Orange

Safety

WGK Germany 

3

HS Code 

2933599550

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

Cetirizine Ethyl Ester (USP RC A) Chemical Properties,Usage,Production

Uses

Cetirizine Ethyl Ester, is an intermediate for the preparation of Cetirizine (C281100), which is a nonsedating type histamine H1-receptor antagonist. It is an antihistamine used in the treatment of allergies, hay fever, angioedema, and urticaria. It is a major metabolite of Hydroxyzine (H996500).

Uses

Cetirizine Ethyl Ester is the impurity of Cetirizine(C281101), is an antihistamine used in treatment of children with chronic spontaneous urticaria.