4-Chlorobenzhydrol

Product Name: 4-Chlorobenzhydrol
CAS No.: 119-56-2
Chemical Name: 4-Chlorobenzhydrol
Synonyms: Chlorobenzhydrol;Cetirizine 4-Chlorobenzhydrol Impurity;AURORA KA-7061;4-CHLOROBENZHYDROL;Meclizine USP RC A;P-CHLORO BENZHYDROL;4-Chlorobenzohydrol;p-Chlorobenzohydrol;Benzhydrol, p-chloro-;Benzhydrol, 4-chloro-
CBNumber: CB6151432
Molecular Formula: C13H11ClO
Formula Weight: 218.68
MOL File: 119-56-2.mol

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4-Chlorobenzhydrol Property

Melting point:: 58-60 °C (lit.)
Boiling point:: 150-151°C 2,6mm
Density: 1.1178 (rough estimate)
refractive index: 1.5260 (estimate)
Flash point:: 150-151°C/2.6mm
storage temp.: 2-8°C
solubility: insoluble
pka: 13.34±0.20(Predicted)
color: White to Off-White
Water Solubility: insoluble
BRN: 2050235
CAS DataBase Reference: 119-56-2(CAS DataBase Reference)
NIST Chemistry Reference: Benzenemethanol, 4-chloro-«alpha»-phenyl-(119-56-2)
EPA Substance Registry System: Benzenemethanol, 4-chloro-.alpha.-phenyl- (119-56-2)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 24/25-36-26
WGK Germany: 3
TSCA: Yes
HS Code: 29062990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3034
Product name: Meclizine Related Compound A
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 30MG
Price: $460
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1377010
Product name: Meclizine Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15mg
Price: $1490
Updated: 2024/03/01

Sigma-Aldrich

Product number: 124982
Product name: 4-Chlorobenzhydrol
Purity: 98%
Packaging: 1g
Price: $12.48
Updated: 2024/03/01

TCI Chemical

Product number: C0989
Product name: 4-Chlorobenzhydrol
Purity: >98.0%(GC)
Packaging: 25g
Price: $36
Updated: 2024/03/01

TCI Chemical

Product number: C0989
Product name: 4-Chlorobenzhydrol
Purity: >98.0%(GC)
Packaging: 500g
Price: $349
Updated: 2024/03/01

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4-Chlorobenzhydrol Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

4-Chlorobenzhydrol was used as internal standard to measure the N-demethyl antipyrine metabolite in urine by gas chromatography-mass spectrometry. It was also used in the identification of the antihistamine cetirizine as a relevant cross-reactant for the carbamazepine-specific enzyme-linked immunosorbent assay .

Preparation

Preparation of 4-Chlorobenzhydrol(4-CB):
about 5.0g(0.023 mol) of 4-chloro benzophenone was dissolved in 15 mL of isopropyl alcohol (IPA) and heated to 50°C followed by the addition of 0.265g(0.007 mol) of sodium borohydride as a lot with the temperature maintained at 65°C for 2 h. The reaction mixture was distilled to expel isopropyl alcohol up to 90 %. The resulting solution was cooled and treated with dil HCl (5 mL of conc. HCl in 20 mL of water). Finally the reaction mass was extracted with 15 mL of toluene. The toluene extract was washed withwater to pH-7. The compound obtained in this step was taken to next step without isolation but aliquot sample was concentrated, isolated and checked for melting point (m.p. = 58-60°C).

Definition

ChEBI: P-Chlorobenzhydrol is a diarylmethane.

4-Chlorobenzhydrol Preparation Products And Raw materials

Raw materials

ZINC Water Benzoyl chloride Aluminium chloride hexahydrate

Preparation Products

CLOPERASTINE Chlorcyclizine hydrochloride 4-Chlorobenzhydrylchloride 1-(4-Chlorobenzhydryl)piperazine CHLORCYCLIZINE (4-CHLORODIPHENYL)METHYL BETA-CHLOROETHYL ETHER

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4-Chlorobenzhydrol Suppliers

Americas 1 Austria 1 Canada 1 China 230 Europe 2 Germany 3 India 24 Japan 2 Slovakia 1 South Korea 1 Switzerland 3 Ukraine 2 United Kingdom 11 United States 33 Global 315

Shaanxi Zhong Zhi Biao Pin Pharmaceutical technology Co., LTD

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Energy Chemical

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Adamas Reagent, Ltd.

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Nanjing Chemlin Chemical Co., Ltd

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View Lastest Price from 4-Chlorobenzhydrol manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 4-Chlorobenzhydrol 119-56-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-01

Hebei Yanxi Chemical Co., Ltd.

Product: 4-Chlorobenzhydrol 119-56-2
Price: US $30.00-10.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-11-17

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 4-Chlorobenzhydrol 119-56-2
Price: US $99.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1 ton
Release date: 2021-12-21

119-56-2, 4-ChlorobenzhydrolRelated Search:

Ethyl acetate Benzyl alcohol Benzhydrol 2-(2-Hydroxyethyl)pyridine 2-Vinylpyridine (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride 4-(DIPHENYLMETHYL)-1-PIPERAZINEETHANOL DIHYDROCHLORIDE 1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE 4-Chlorobenzophenone iperazineacetic acid, 4-[(4- chlorophenyl)phenylMethyl]- Cetirizine 3-Chloro IMpurity Dihydrochloride 1-(4-Chlorobenzhydryl)piperazine Cetirizine-d<sub>4</sub> CETIRIZINE-D8 Clemastine fumarate Fenarimol ROSE BENGAL 4,4'-DICHLORO-ALPHA-METHYLBENZHYDROL

(4-Chlorophenyl)phenylmethanol

4-chloro-alpha-phenyl-benzenemethano

4-Chlorobenzohydrol

Benzhydrol, 4-chloro-

Benzhydrol, p-chloro-

Chlorobenzhydrol

AURORA KA-7061

P-CHLORO BENZHYDROL

4-CHLOROPHENYL PHENYL CARBINOL

4-CHLORO-ALPHA-PHENYL-BENZENEMETHANOL

4-CHLORO-(ALPHA-PHENYL) BENZYL ALCOHOL

4-CHLOROBENZHYDROL

4-Chlorobenzhydryl alcohol

4-CHLORO-O-PHENYLBENZYL ALCOHOL

4-CHLORODIPHENYLCARBINOL

4-CHLORODIPHENYLMETHANOL

Benzenemethanol, 4-chloro-.alpha.-phenyl-

4-Chlorodiphenylmethanol~4-Chlororphenyl phenyl carbinol

Cetirizine 4-Chlorobenzhydrol Impurity

Buclizine EP Impurity B

(R)-(4-chlorophenyl)-phenylmethanol

Cetirizine Impurity L

Meclizine USP Related Compound A

4-CHLOROBENZHYDROL 98+%

4-Chloro-a-phenyl-benzenemethanol

4-CHLOROBENZHYDROL pure

4-Chloro-α-phenylbenzenemethanol

(p-Chlorophenyl)phenylmethanol

p-Chlorobenzohydrol

Phenyl(4-chlorophenyl)methanol

Meclizine Related Compound A (15 mg) (4-chlorobenzhydrol)

4-CHLOROBENZHYDROL FOR SYNTHESIS

Buclizine HCl IMpurity-B(BP/EP)

Levocetrizine IMpurity

4-Chloro Benzhydrol (Meclozine EP IMpurity B)

Meclozine EP IMpurity B (4-Chlorobenzhydrol)

BenzeneMethanol, 4-chloro-α-phenyl-

Meclozine impurity B

Cetirizine 4-Chlorobenzhydrol Impurity (USP)

Meclizine USP RC A

4-Chlorobenzhydrol 98%

Cetirizine Impurity I

4-Chlorobenzhydrol &gt

Meclozine impurity B CRS

N-Methyl-2-(pyridin-2-yl)-N-[2-(pyr

Meclizine EP Impurity B

Levocloperastine CBZ Racemate

Meclozine EP Impurity B

Meclozine imp-B/4-Chlorobenzhydrol

Cetrizine 4-chlorobenzyhydrol Impurity

Meclizine Related Compound A (Cetirizine 4-Chlorobenzhydrol Impurity)

Cetirizine 4-Chlorobenzhydrol Impurity (Meclizine Related Compound A)

Cetirizine Impurity93

4-ChlorobenzhydrolQ: What is 4-Chlorobenzhydrol Q: What is the CAS Number of 4-Chlorobenzhydrol Q: What is the storage condition of 4-Chlorobenzhydrol Q: What are the applications of 4-Chlorobenzhydrol

Meclozine Dihydrochloride Impurity B

Meclozine EP Impurity B (Meclizine USP Related Compound A, 4-Chlorobenzhydrol)

Cinnarizine Impurity 12

Meclozine Dihydrochloride EP Impurity B