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4-Chlorobenzhydrol

Product Name
4-Chlorobenzhydrol
CAS No.
119-56-2
Chemical Name
4-Chlorobenzhydrol
Synonyms
Chlorobenzhydrol;Cetirizine 4-Chlorobenzhydrol Impurity;AURORA KA-7061;4-CHLOROBENZHYDROL;Meclizine USP RC A;P-CHLORO BENZHYDROL;4-Chlorobenzohydrol;p-Chlorobenzohydrol;Benzhydrol, p-chloro-;Benzhydrol, 4-chloro-
CBNumber
CB6151432
Molecular Formula
C13H11ClO
Formula Weight
218.68
MOL File
119-56-2.mol
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4-Chlorobenzhydrol Property

Melting point:
58-60 °C (lit.)
Boiling point:
150-151°C 2,6mm
Density 
1.1178 (rough estimate)
refractive index 
1.5260 (estimate)
Flash point:
150-151°C/2.6mm
storage temp. 
2-8°C
solubility 
insoluble
pka
13.34±0.20(Predicted)
color 
White to Off-White
Water Solubility 
insoluble
BRN 
2050235
CAS DataBase Reference
119-56-2(CAS DataBase Reference)
NIST Chemistry Reference
Benzenemethanol, 4-chloro-«alpha»-phenyl-(119-56-2)
EPA Substance Registry System
Benzenemethanol, 4-chloro-.alpha.-phenyl- (119-56-2)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
TSCA 
Yes
HS Code 
29062990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3034
Product name
Meclizine Related Compound A
Purity
pharmaceutical secondary standard, certified reference material
Packaging
30MG
Price
$460
Updated
2024/03/01
Sigma-Aldrich
Product number
1377010
Product name
Meclizine Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
15mg
Price
$1490
Updated
2024/03/01
Sigma-Aldrich
Product number
124982
Product name
4-Chlorobenzhydrol
Purity
98%
Packaging
1g
Price
$12.48
Updated
2024/03/01
TCI Chemical
Product number
C0989
Product name
4-Chlorobenzhydrol
Purity
>98.0%(GC)
Packaging
25g
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
C0989
Product name
4-Chlorobenzhydrol
Purity
>98.0%(GC)
Packaging
500g
Price
$349
Updated
2024/03/01
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4-Chlorobenzhydrol Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

4-Chlorobenzhydrol was used as internal standard to measure the N-demethyl antipyrine metabolite in urine by gas chromatography-mass spectrometry. It was also used in the identification of the antihistamine cetirizine as a relevant cross-reactant for the carbamazepine-specific enzyme-linked immunosorbent assay .

Preparation

Preparation of 4-Chlorobenzhydrol(4-CB):
about 5.0g(0.023 mol) of 4-chloro benzophenone was dissolved in 15 mL of isopropyl alcohol (IPA) and heated to 50°C followed by the addition of 0.265g(0.007 mol) of sodium borohydride as a lot with the temperature maintained at 65°C for 2 h. The reaction mixture was distilled to expel isopropyl alcohol up to 90 %. The resulting solution was cooled and treated with dil HCl (5 mL of conc. HCl in 20 mL of water). Finally the reaction mass was extracted with 15 mL of toluene. The toluene extract was washed withwater to pH-7. The compound obtained in this step was taken to next step without isolation but aliquot sample was concentrated, isolated and checked for melting point (m.p. = 58-60°C).

Definition

ChEBI: P-Chlorobenzhydrol is a diarylmethane.

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4-Chlorobenzhydrol Suppliers

Nanjing XiLang Chemical Products Co., Ltd.
Tel
025-5276156 18936048580
Email
chemxilang@163.com
Country
China
ProdList
4009
Advantage
58
Shaanxi Zhong Zhi Biao Pin Pharmaceutical technology Co., LTD
Tel
029-89239927 18009291534
Email
18009291534@163.com
Country
China
ProdList
323
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2210
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Jinxiang Chemical (Danyang) Products Co., Ltd.
Tel
025-86819862 13913839793
Fax
0086-25-86819859
Email
nancyzong@jinchemical.com
Country
China
ProdList
97
Advantage
74
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
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View Lastest Price from 4-Chlorobenzhydrol manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
4-Chlorobenzhydrol 119-56-2
Price
US $30.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-11-17
Hebei Guanlang Biotechnology Co., Ltd.
Product
4-Chlorobenzhydrol 119-56-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2023-02-17
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
4-Chlorobenzhydrol 119-56-2
Price
US $99.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1 ton
Release date
2021-12-21

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