ChemicalBook > CAS DataBase List > 2,4-Dihydroxybenzamide

2,4-Dihydroxybenzamide

Product Name
2,4-Dihydroxybenzamide
CAS No.
3147-45-3
Chemical Name
2,4-Dihydroxybenzamide
Synonyms
β-Resorcylamide;B-RESORCYL AMIDE;p-hydroxysaliamide;P-Hydroxysalicylamide;2,4-dihydroxy-benzamid;4-HYDROXY SALICYLAMIDE;2,4-DIHYDROXYBENZAMIDE;β-Resorcylic acid amide;2,4-Dihydroxybenzamide>Benzamide, 2,4-dihydroxy-
CBNumber
CB0267944
Molecular Formula
C7H7NO3
Formula Weight
153.14
MOL File
3147-45-3.mol
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2,4-Dihydroxybenzamide Property

Melting point:
228 °C
Boiling point:
455.8±15.0 °C(Predicted)
Density 
1.458±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
8.15±0.10(Predicted)
color 
White to Light red to Green
InChI
InChI=1S/C7H7NO3/c8-7(11)5-2-1-4(9)3-6(5)10/h1-3,9-10H,(H2,8,11)
InChIKey
IIUJCQYKTGNRHH-UHFFFAOYSA-N
SMILES
C(N)(=O)C1=CC=C(O)C=C1O
CAS DataBase Reference
3147-45-3(CAS DataBase Reference)
EPA Substance Registry System
Benzamide, 2,4-dihydroxy- (3147-45-3)
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Safety

HS Code 
2924.29.7790
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D3460
Product name
2,4-Dihydroxybenzamide
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
D3460
Product name
2,4-Dihydroxybenzamide
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$79
Updated
2024/03/01
TRC
Product number
D678945
Product name
2,4-Dihydroxybenzamide
Packaging
100mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0007919
Product name
2,4-DIHYDROXYBENZAMIDE
Purity
95.00%
Packaging
5G
Price
$816.19
Updated
2021/12/16
AK Scientific
Product number
J93198
Product name
2,4-Dihydroxybenzamide
Packaging
5g
Price
$40
Updated
2021/12/16
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2,4-Dihydroxybenzamide Chemical Properties,Usage,Production

Uses

2,4-Dihydroxybenzamide is a specific inhibitor of glutathione reductase.

Synthesis

General procedure for preparation of 2,4-dihydroxybenzamide. It was prepared by the addition of 1.69 g (0.10 mol) methyl 2,4-dihydroxybenzoate in 10 mL of ammonia (pro analysis, 25% in water). The reaction mixture was stirred for 24 hours at room temperature. The excess ammonia and methanol formed during the reaction were removed under reduced pressure. Upon addition of 10 mL of water, the product was extracted by ether. Ether extracts were collected and washed with water, and after separation, the ether layer was dried over anhydrous sodium sulfate and evaporated under reduced pressure to give 2,4-dihydroxy benzamide. Crude products were purified by column chromatography using ethyl acetate as a mobile phase[1].

References

[1] Milena Jadrijevi?-Mladar Takac, Drazen Viki? Topi?. “FT-IR and NMR spectroscopic studies of salicylic acid derivatives. II. Comparison of 2-hydroxy- and 2,4- and 2,5-dihydroxy derivatives.” Acta Pharmaceutica 54 3 (2004): 177–91.

2,4-Dihydroxybenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-Dihydroxybenzamide Suppliers

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View Lastest Price from 2,4-Dihydroxybenzamide manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2,4-Dihydroxybenzamide 3147-45-3
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 mt
Release date
2024-11-19
Hebei Mojin Biotechnology Co., Ltd
Product
2,4-Dihydroxybenzamide 3147-45-3
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000KG
Release date
2023-08-25
LY Global chemicals co.,ltd .
Product
2,4-Dihydroxybenzamide 3147-45-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%Min
Supply Ability
1000kg
Release date
2023-03-12

3147-45-3, 2,4-DihydroxybenzamideRelated Search:

2,4-Dihydroxybenzoic acid 4-Hydroxybenzamide Protocatechuic acid Benzamide Chlorantraniliprole 2,4-DIHYDROXYBENZHYDRAZIDE 2,4-Dihydroxy-N-(2-hydroxyethyl)benzamide 3,4-DIHYDROXYBENZAMIDE 4-Bromo-3,5-dihydroxy-N-methylbenzamide 4-CHLORO-N,2-DIHYDROXYBENZAMIDE N,2-DIHYDROXYBENZAMIDE 4-BROMO-3,5-DIHYDROXYBENZAMIDE 5-CHLORO-N,2-DIHYDROXYBENZAMIDE 3,5-DIHYDROXYBENZAMIDE 2,6-DIHYDROXYBENZAMIDE,2 6-DIHYDROXYBENZAMIDE 95% Salicylamide L371,257 2,5-dihydroxybenzamide

  • B-RESORCYL AMIDE
  • 2,4-DIHYDROXY BENZOYLAMINE
  • 2,4-DIHYDROXYBENZAMIDE
  • 4-HYDROXY SALICYLAMIDE
  • 2,4-Dihydroxybenzamide(P-Hydroxysalicylamide)
  • 2,4-dihydroxy-benzamid
  • p-hydroxysaliamide
  • P-Hydroxysalicylamide
  • 4-HYDROXYSALICYLAMIDE / 2,4-DIHYDROXYBENZAMIDE
  • 4-HYDROXY SALICYLAMIDE HPLC 98.5+%
  • β-Resorcylamide
  • β-Resorcylic acid amide
  • 2,4-Dihydroxybenzamide&gt
  • Benzamide, 2,4-dihydroxy-
  • 2,4-Dihydroxybenzamide ISO 9001：2015 REACH
  • 3147-45-3
  • 2147-45-3
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts