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Volitinib

Product Name
Volitinib
CAS No.
1313725-88-0
Chemical Name
Volitinib
Synonyms
Savolitinib;HMPL-504;Savolitinib (AZD6094);CS-2676;Volitinib;AZD-6094);EOS-60799;HMPL0-504;Volitinib USP/EP/BP;AZD-6094 (VOLITINIB)
CBNumber
CB02731160
Molecular Formula
C17H15N9
Formula Weight
345.36
MOL File
1313725-88-0.mol
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Volitinib Property

Melting point:
205-207°C
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
5.67±0.50(Predicted)
form 
Solid
color 
Pale Beige
CAS DataBase Reference
1313725-88-0
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
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N-Bromosuccinimide Price

TRC
Product number
S142903
Product name
Savolitinib
Packaging
100mg
Price
$1215
Updated
2021/12/16
ChemScene
Product number
CS-4062
Product name
Savolitinib
Purity
99.56%
Packaging
100mg
Price
$850
Updated
2021/12/16
ChemScene
Product number
CS-4062
Product name
Savolitinib
Purity
99.56%
Packaging
5mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
BV160378
Product name
Volitinib
Packaging
5mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
BV160378
Product name
Volitinib
Packaging
50mg
Price
$600
Updated
2021/12/16
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Volitinib Chemical Properties,Usage,Production

Description

Savolitinib selectively inhibits the MET receptor, blocking the PI3K/AKT/MAPK-signaling pathway as well as downregulating MYC.

Uses

Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.

Clinical Use

It is currently being evaluated in phase I clinical trials in combination with EGFR TKIs in NSCLC patients.

Volitinib Preparation Products And Raw materials

Raw materials

Preparation Products

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Volitinib Suppliers

DKMbiochem.Co. Ltd
Tel
15901859516
Fax
15901859516
Email
sales@DKMbiochem.com
Country
China
ProdList
344
Advantage
58
CAREBIO PHARMA
Tel
18501057619
Email
771737847@qq.com
Country
China
ProdList
61
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
28-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
510
Advantage
57
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Shanghai Hope Chem Co., Ltd.,
Tel
+21-18501659228 18501659228
Fax
sales@hope-chem.com
Email
info@hope-chem.com
Country
China
ProdList
482
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq:2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Wuhan Kaymke Chemical Co., Ltd.,
Tel
027-027-87342388 18086026008
Fax
027-87342388
Email
sales@kaymke.com
Country
China
ProdList
3872
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
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View Lastest Price from Volitinib manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Savolitinib 1313725-88-0
Price
US $38.99/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2021-12-27
Dideu Industries Group Limited
Product
Volitinib 1313725-88-0
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-05
Career Henan Chemical Co
Product
(S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine 1313725-88-0
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-01

1313725-88-0, VolitinibRelated Search:


  • AZD6094,Volitinib, HMPL-504, Savolitinib
  • 1-[(1S)-1-Imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine
  • (S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine
  • Volitinib
  • Savolitinib
  • HMPL-504(AZD6094, Volitinib)
  • EOS-60799
  • AZD-6094)
  • HMPL-504
  • Savolitinib (Volitinib
  • (S)-1-(1-(imidazo[1,2-a] yridine-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine
  • Savolitinib (AZD6094)
  • (S)-1-(1-(IMIDAZO[1,2-A]
  • HMPL-504; HMPL504; HMPL504; AZD-6094; AZD 6094; AZD6094
  • Volitinib (Savolitinib, AZD-6094)
  • CS-2676
  • VOLITINIB; HMPL504; AZD-6094;VOLITINIB; HMPL-504; AZD6094; HMPL 504; AZD 6094
  • Savolitinib(AZD6094, HMPL-504)
  • 1H-1,2,3-Triazolo[4,5-b]pyrazine, 1-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-
  • Volitinib USP/EP/BP
  • 4-{1-[(1S)-1-{imidazo[1,2-a]pyridin-6-yl}ethyl]-1H-[ 1,2,3]triazolo[4,5-b]pyrazin-6-yl}-1-methyl-1H-pyra zole
  • Pharmaceutical Intermediate Volitinib
  • AZD-6094 (VOLITINIB)
  • VOLITINIB (AZD6094, SAVOLITINIB)
  • HMPL0-504
  • 1313725-88-0
  • API