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Volitinib

Product Name
Volitinib
CAS No.
1313725-88-0
Chemical Name
Volitinib
Synonyms
Savolitinib;HMPL-504;Savolitinib (AZD6094);CS-2676;Volitinib;AZD-6094);EOS-60799;HMPL0-504;Volitinib USP/EP/BP;AZD-6094 (VOLITINIB)
CBNumber
CB02731160
Molecular Formula
C17H15N9
Formula Weight
345.36
MOL File
1313725-88-0.mol
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Volitinib Property

Melting point:
205-207°C
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
5.67±0.50(Predicted)
form 
Solid
color 
Pale Beige
CAS DataBase Reference
1313725-88-0
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
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N-Bromosuccinimide Price

TRC
Product number
S142903
Product name
Savolitinib
Packaging
100mg
Price
$1215
Updated
2021/12/16
ChemScene
Product number
CS-4062
Product name
Savolitinib
Purity
99.56%
Packaging
100mg
Price
$850
Updated
2021/12/16
ChemScene
Product number
CS-4062
Product name
Savolitinib
Purity
99.56%
Packaging
5mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
BV160378
Product name
Volitinib
Packaging
5mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
BV160378
Product name
Volitinib
Packaging
50mg
Price
$600
Updated
2021/12/16
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Volitinib Chemical Properties,Usage,Production

Description

Savolitinib selectively inhibits the MET receptor, blocking the PI3K/AKT/MAPK-signaling pathway as well as downregulating MYC.

Uses

Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.

Clinical Use

It is currently being evaluated in phase I clinical trials in combination with EGFR TKIs in NSCLC patients.

Volitinib Preparation Products And Raw materials

Raw materials

Preparation Products

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Volitinib Suppliers

China 118 India 1 United States 8 Global 127
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
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View Lastest Price from Volitinib manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Savolitinib 1313725-88-0
Price
US $38.99/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2021-12-27
Dideu Industries Group Limited
Product
Volitinib 1313725-88-0
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-05
Career Henan Chemical Co
Product
(S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine 1313725-88-0
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-01

1313725-88-0, VolitinibRelated Search:

3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione INCB39110 X-376 Filgotinib Decernotinib Masitinib Lestaurtinib CAL-101 PLX3397 (Pexidartinib) CO-1686 Momelotinib Verteporfin PLX4032 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol AZD-6244 ARRY-334543 SU 6668 Ibrutinib

  • AZD6094,Volitinib, HMPL-504, Savolitinib
  • 1-[(1S)-1-Imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine
  • (S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine
  • Volitinib
  • Savolitinib
  • HMPL-504(AZD6094, Volitinib)
  • EOS-60799
  • AZD-6094)
  • HMPL-504
  • Savolitinib (Volitinib
  • (S)-1-(1-(imidazo[1,2-a] yridine-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine
  • Savolitinib (AZD6094)
  • (S)-1-(1-(IMIDAZO[1,2-A]
  • HMPL-504; HMPL504; HMPL504; AZD-6094; AZD 6094; AZD6094
  • Volitinib (Savolitinib, AZD-6094)
  • CS-2676
  • VOLITINIB; HMPL504; AZD-6094;VOLITINIB; HMPL-504; AZD6094; HMPL 504; AZD 6094
  • Savolitinib(AZD6094, HMPL-504)
  • 1H-1,2,3-Triazolo[4,5-b]pyrazine, 1-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-
  • Volitinib USP/EP/BP
  • 4-{1-[(1S)-1-{imidazo[1,2-a]pyridin-6-yl}ethyl]-1H-[ 1,2,3]triazolo[4,5-b]pyrazin-6-yl}-1-methyl-1H-pyra zole
  • Pharmaceutical Intermediate Volitinib
  • AZD-6094 (VOLITINIB)
  • VOLITINIB (AZD6094, SAVOLITINIB)
  • HMPL0-504
  • 1313725-88-0
  • API