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Everolimus Ring-Opening Impurity

Product Name
Everolimus Ring-Opening Impurity
CAS No.
1708118-13-1
Chemical Name
Everolimus Ring-Opening Impurity
Synonyms
Everolimus Impurity 33;Everolimus impurity 42;Everolimus Impurity 012-99;Everolimus Open-Ring Impurity;Everolimus Impurity 2（012-99）;Everolimus Impurity 3 (012-99);Everolimus Open-Ring Aldehyde Impurity;EverolimusRetroaldolDegradationProduct;(S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy);Everolimus Ring-Opening Impurity (Mixture of Isomers)
CBNumber
CB02737607
Molecular Formula
C53H83NO14
Formula Weight
958.23
MOL File
1708118-13-1.mol
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Everolimus Ring-Opening Impurity Property

Melting point:
45-50°C
Boiling point:
954.8±75.0 °C(predicted)
Density 
1.15±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
storage temp. 
Amber Vial, -86°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
10.56±0.60(predicted)
color 
White to Off-White
Stability:
Light and temperature Sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E945420
Product name
EverolimusRetroaldolDegradationProduct
Packaging
1mg
Price
$185
Updated
2021/12/16
TRC
Product number
E945420
Product name
EverolimusRetroaldolDegradationProduct
Packaging
10mg
Price
$1455
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0028015
Product name
EVEROLIMUS IMPURITY D
Purity
95.00%
Packaging
1MG
Price
$950.03
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0028015
Product name
EVEROLIMUS IMPURITY D
Purity
95.00%
Packaging
10MG
Price
$2550
Updated
2021/12/16
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Everolimus Ring-Opening Impurity Chemical Properties,Usage,Production

Uses

Everolimus Retroaldol Degradation Product is an impurity of Everolimus (E945400). Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Everolimus Impurity D

Everolimus Ring-Opening Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Everolimus Ring-Opening Impurity Suppliers

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1708118-13-1, Everolimus Ring-Opening ImpurityRelated Search:

Everolimus Impurity 1 EveroliMus iMpurity Everolimus Related Compound 2 Everolimus Related Compound 3 Everolimus O-Ethyl Impurity 2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate Everolimus Rapamycin EveroliMus-d4 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Everolimus EP Impurity E USDOYNAPNXMXOE-SPSCNLKESA-N 23,27-Epoxy(7E,15E,17E,19E)-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexam... Rapamycin, 32-O-demethyl- Seco Rapamycin Everolimus Hydrolized Impurity 28-epirapamycin 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone

  • EverolimusRetroaldolDegradationProduct
  • (S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)
  • Everolimus Impurity 012-99
  • Everolimus Open-Ring Impurity
  • Everolimus Open-Ring Aldehyde Impurity
  • Everolimus Impurity 33
  • (2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl (S)-1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate
  • (S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-Hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate
  • Everolimus Impurity 2（012-99）
  • 2-Piperidinecarboxylic acid, 1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrien-1-yl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]-2-oxoacetyl]-, (1S,4R,5E)-1-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-4,6-dimethyl-3,7-d...
  • Everolimus Ring-Opening Impurity (Mixture of Isomers)
  • EVEROLIMUS RETROALDOL DEGRADATION (ISOMER 1 + ISOMER 2)
  • 2-Piperidinecarboxylic acid, 1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrien-1-yl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]-2-oxoacetyl]-, (1S,4R,5E)-1-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-4,6-dimethyl-3,7-dioxo-5-hepten-1-yl ester, (2S)-
  • Everolimus impurity 42
  • Everolimus Impurity 3 (012-99)
  • 1708118-13-1